eMedicine Specialties > Emergency Medicine > Obstetrics & Gynecology

Abruptio Placentae: Differential Diagnoses & Workup

Author: Slava V Gaufberg, MD, Assistant Professor of Medicine, Harvard Medical School; Director of Transitional Residency Training Program, Cambridge Health Alliance
Contributor Information and Disclosures

Updated: Dec 12, 2008

Differential Diagnoses

Abdominal Trauma, Blunt
Pregnancy, Ectopic
Appendicitis, Acute
Pregnancy, Preeclampsia
Disseminated Intravascular Coagulation
Pregnancy, Trauma
Ovarian Cysts
Shock, Hemorrhagic
Ovarian Torsion
Shock, Hypovolemic
Placenta Previa
Vaginitis
Pregnancy, Delivery

Workup

Laboratory Studies

  • Hemoglobin
  • Hematocrit
  • Platelets
  • Prothrombin time/activated partial thromboplastin time
  • Fibrinogen
  • Fibrin/fibrinogen degradation products
  • D-dimer
  • Blood type

Imaging Studies

  • Ultrasonography helps determine the location of the placenta to exclude placenta previa. Ultrasonography is not very useful in diagnosing placental abruption.
    • Retroplacental hematoma may be recognized in 2-25% of all abruptions.
    • Recognition of retroplacental hematoma depends on the degree of hematoma and on the operator's skill level.

More on Abruptio Placentae

Overview: Abruptio Placentae
Differential Diagnoses & Workup: Abruptio Placentae
Treatment & Medication: Abruptio Placentae
Follow-up: Abruptio Placentae
References

References

  1. Ananth CV, Oyelese Y, Yeo L, et al. Placental abruption in the United States, 1979 through 2001: temporal trends and potential determinants. Am J Obstet Gynecol. Jan 2005;192(1):191-8. [Medline].

  2. Broers T, King WD, Arbuckle TE, Liu S. The occurrence of abruptio placentae in Canada: 1990 to 1997. Chronic Dis Can. 2004;25(2):16-20. [Medline].

  3. Dahmus MA, Sibai BM. Blunt abdominal trauma: are there any predictive factors for abruptio placentae or maternal-fetal distress?. Am J Obstet Gynecol. Oct 1993;169(4):1054-9. [Medline].

  4. Green JR. Placental abnormalities: Placenta previa and abruptio placentae. In: Creasy RK, Resnik R, eds. Maternal Fetal Medicine. Philadelphia, Pa: WB Saunders; 1984:539.

  5. Lowe TW, Cunningham FG. Placental abruption. Clin Obstet Gynecol. Sep 1990;33(3):406-13. [Medline].

  6. Morgan MA, Berkowitz KM, Thomas SJ, et al. Abruptio placentae: perinatal outcome in normotensive and hypertensive patients. Am J Obstet Gynecol. Jun 1994;170(6):1595-9. [Medline].

  7. Nolan TE, Smith RP, Devoe LD. A rapid test for abruptio placentae: evaluation of a D-dimer latex agglutination slide test. Am J Obstet Gynecol. Aug 1993;169(2 Pt 1):265-8; discussion 268-9. [Medline].

  8. Plunkett J, Borecki I, Morgan T, et al. Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia. BMC Genet. Jul 8 2008;9:44. [Medline].

  9. Pritchard JA, Mason R, Corley M, Pritchard S. Genesis of severe placental abruption. Am J Obstet Gynecol. Sep 1 1970;108(1):22-7. [Medline].

  10. Signore C, Mills JL, Qian C, et al. Circulating angiogenic factors and placental abruption. Obstet Gynecol. Aug 2006;108(2):338-44. [Medline].

  11. Steer PL, Finley BE, Blumenthal LA. Abruptio placentae and disseminated intravascular coagulation: use of thrombelastography and sonoclot analysis. Int J Obstet Anesth. 1994;3(4):229-233. [Medline].

  12. Steinborn A, Seidl C, Sayehli C, et al. Anti-fetal immune response mechanisms may be involved in the pathogenesis of placental abruption. Clin Immunol. Jan 2004;110(1):45-54. [Medline].

  13. Tikkanen M, Nuutila M, Hiilesmaa V. Clinical presentation and risk factors of placental abruption. Acta Obstet Gynecol Scand. 2006;85(6):700-5. [Medline].

  14. Toivonen S, Heinonen S, Anttila M, et al. Obstetric prognosis after placental abruption. Fetal Diagn Ther. Jul-Aug 2004;19(4):336-41. [Medline].

Further Reading

Keywords

abruptio placentae, placental abruption, cesarean delivery, cesarean birth, cesarean section, c-section, Couvelaire uterus, separation of the placenta, vaginal bleeding, abdominal pain, back pain, uterine tenderness, fetal distress, abnormal uterine contractions, idiopathic premature labor, fetal death

Contributor Information and Disclosures

Author

Slava V Gaufberg, MD, Assistant Professor of Medicine, Harvard Medical School; Director of Transitional Residency Training Program, Cambridge Health Alliance
Slava V Gaufberg, MD is a member of the following medical societies: American College of Emergency Physicians
Disclosure: Nothing to disclose.

Medical Editor

Roy Alson, MD, PhD, FACEP, FAAEM, Associate Professor, Department of Emergency Medicine, Wake Forest University School of Medicine; Medical Director, Forsyth County EMS; Deputy Medical Advisor, North Carolina Office of EMS; Associate Medical Director, North Carolina Baptist AirCare
Roy Alson, MD, PhD, FACEP, FAAEM is a member of the following medical societies: American College of Emergency Physicians, American Medical Association, National Association of EMS Physicians, North Carolina Medical Society, Society for Academic Emergency Medicine, and Wilderness Medical Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Mark Zwanger, MD, MBA, Assistant Professor, Department of Emergency Medicine, Thomas Jefferson University
Mark Zwanger, MD, MBA is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and American Medical Association
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Pamela L Dyne, MD, Professor of Clinical Medicine/Emergency Medicine, David Geffen School of Medicine at UCLA; Attending Physician, Department of Emergency Medicine, Olive View-UCLA Medical Center
Pamela L Dyne, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

 
 
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