Dysmenorrhea in Emergency Medicine Workup

  • Author: Andre Holder, MD; Chief Editor: Pamela L Dyne, MD   more...
 
Updated: Apr 15, 2011
 

Laboratory Studies

Laboratory studies may be indicated to elucidate the cause of secondary dysmenorrhea.

  • Complete blood count (with differential), for evidence of infection or neoplastic process
  • Urinalysis, to exclude urinary tract infection
  • Quantitative human chorionic gonadotropin level, to exclude ectopic pregnancy
  • Gonococcal/chlamydial cultures, enzyme immunoassay (EIA), and DNA probe testing, to exclude sexually transmitted infections (STIs)/pelvic inflammatory disease (PID)
  • Stool guaiac, to rule out GI bleeding
  • Erythrocyte sedimentation rate (ESR), for subacute salpingitis

Although these tests can be used as adjuncts in the workup of dysmenorrhea, they may be misleading. For instance, the CBC may show a normal white count in up to 56% of patients with PID. Conversely, the white count can be elevated from physiologic stress. In a patient with associated vaginal bleeding, the hematocrit may be normal in a patient with obvious hypovolemia on examination (eg, positive orthostasis or tachycardia), especially if hemorrhage started within minutes to hours of presentation.[4] Moreover, the EIA and DNA probe tests for gonorrhea and chlamydia have varying sensitivities, anywhere from 86-93%.[4] Therefore, ancillary laboratory testing should not replace a sound clinical basis for diagnosis of dysmenorrhea and its underlying cause.

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Imaging Studies

In cases of well-established primary dysmenorrhea, imaging studies are of little value. However, if pelvic pathology is suspected, abdominal and/or transvaginal ultrasonography are inexpensive and effective modalities.

  • Ultrasonography is relatively noninvasive, can easily be performed in the ED, and reveals most relevant pelvic pathology. For instance, endometriosis may appear as a complex mass with a speckled appearance.[4]
  • Although CT scanning is not routinely ordered in the ED for patients with dysmenorrhea, it does have some utility, particularly in identifying ovarian torsion.[4, 7, 6]
  • MRI has some ability to detect adenomyosis and submucous myomas that might otherwise be missed on other imaging modalities.[4] This test is not routinely ordered in the ED.
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Procedures

Further investigation outside the ED might include hysterosalpingoscopy or laparoscopy. The latter is usually indicated when initial interventions fail to relieve symptoms.

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Contributor Information and Disclosures
Author

Andre Holder, MD  Staff Physician, Departments of Emergency Medicine and Internal Medicine, Jacobi Medical Center

Andre Holder, MD, is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and National Medical Association

Disclosure: Nothing to disclose.

Coauthor(s)

Laurel D Edmundson, MD  Clinical Assistant Instructor of Emergency Medicine, Resident, Department of Emergency Medicine, Kings County Hospital Center, Brooklyn

Laurel D Edmundson, MD is a member of the following medical societies: American Medical Association and Medical Society of the State of New York

Disclosure: Nothing to disclose.

Mert Erogul, MD  Assistant Professor of Emergency Medicine, University Hospital of Brooklyn: Consulting Staff, Department of Emergency Medicine, Kings County Hospital Center

Mert Erogul, MD is a member of the following medical societies: American College of Emergency Physicians, American Medical Association, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Steven A Conrad, MD, PhD  Chief, Department of Emergency Medicine; Chief, Multidisciplinary Critical Care Service, Professor, Department of Emergency and Internal Medicine, Louisiana State University Health Sciences Center

Steven A Conrad, MD, PhD is a member of the following medical societies: American College of Chest Physicians, American College of Critical Care Medicine, American College of Emergency Physicians, American College of Physicians, International Society for Heart and Lung Transplantation, Louisiana State Medical Society, Shock Society, Society for Academic Emergency Medicine, and Society of Critical Care Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Senior Pharmacy Editor, eMedicine

Disclosure: eMedicine Salary Employment

Mark Zwanger, MD, MBA  Assistant Professor, Department of Emergency Medicine, Jefferson Medical College of Thomas Jefferson University

Mark Zwanger, MD, MBA is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and American Medical Association

Disclosure: Nothing to disclose.

John D Halamka, MD, MS  Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center

John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Chief Editor

Pamela L Dyne, MD  Professor of Clinical Medicine/Emergency Medicine, University of California, Los Angeles, David Geffen School of Medicine; Attending Physician, Department of Emergency Medicine, Olive View-UCLA Medical Center

Pamela L Dyne, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

References
  1. Durain D. Primary dysmenorrhea: assessment and management update. J Midwifery Womens Health. Nov-Dec 2004;49(6):520-8. [Medline].

  2. Proctor ML, Murphy PA, Pattison HM, Suckling J, Farquhar CM. Behavioural interventions for primary and secondary dysmenorrhoea. Cochrane Database Syst Rev. Jul 18 2007;CD002248. [Medline].

  3. French L. Dysmenorrhea. Am Fam Physician. Jan 15 2005;71(2):285-91. [Medline].

  4. Baines PA, Allen GM. Pelvic pain and menstrual related illnesses. Emerg Med Clin North Am. Aug 2001;19(3):763-80. [Medline].

  5. Proctor M, Farquhar C. Diagnosis and management of dysmenorrhoea. BMJ. May 13 2006;332(7550):1134-8. [Medline].

  6. Kalish GM, Patel MD, Gunn ML, Dubinsky TJ. Computed tomographic and magnetic resonance features of gynecologic abnormalities in women presenting with acute or chronic abdominal pain. Ultrasound Q. Sep 2007;23(3):167-75. [Medline].

  7. Kamaya A, Shin L, Chen B, Desser TS. Emergency gynecologic imaging. Semin Ultrasound CT MR. Oct 2008;29(5):353-68. [Medline].

  8. Walker CK, Wiesenfeld HC. Antibiotic therapy for acute pelvic inflammatory disease: the 2006 Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines. Clin Infect Dis. Apr 1 2007;44 Suppl 3:S111-22. [Medline].

  9. Houry D, Abbott JT. Ovarian torsion: a fifteen-year review. Ann Emerg Med. Aug 2001;38(2):156-9. [Medline].

  10. Levy BS, Apgar BS, Surrey ES, Wysocki S. Diagnosis and management: chronic pelvic pain and endometriosis. OBG Management. 2007/03;supp:S3-S13.

  11. Parker JD, Leondires M, Sinaii N, Premkumar A, Nieman LK, Stratton P. Persistence of dysmenorrhea and nonmenstrual pain after optimal endometriosis surgery may indicate adenomyosis. Fertil Steril. Sep 2006;86(3):711-5. [Medline].

  12. Fujiwara H, Konno R, Netsu S, et al. Efficacy of montelukast, a leukotriene receptor antagonist, for the treatment of dysmenorrhea: a prospective, double-blind, randomized, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. Feb 2010;148(2):195-8. [Medline].

  13. Wong CL, Farquhar C, Roberts H, Proctor M. Oral contraceptive pill as treatment for primary dysmenorrhoea. Cochrane Database Syst Rev. Apr 15 2009;CD002120. [Medline].

  14. Ziaei S, Zakeri M, Kazemnejad A. A randomised controlled trial of vitamin E in the treatment of primary dysmenorrhoea. BJOG. Apr 2005;112(4):466-9. [Medline].

  15. Latthe P, Mignini L, Gray R, Hills R, Khan K. Factors predisposing women to chronic pelvic pain: systematic review. BMJ. Apr 1 2006;332(7544):749-55. [Medline].

  16. [Best Evidence] Witt CM, Reinhold T, Brinkhaus B, Roll S, Jena S, Willich SN. Acupuncture in patients with dysmenorrhea: a randomized study on clinical effectiveness and cost-effectiveness in usual care. Am J Obstet Gynecol. Feb 2008;198(2):166.e1-8. [Medline].

  17. Andersch B, Milsom I. An epidemiologic study of young women with dysmenorrhea. Am J Obstet Gynecol. Nov 15 1982;144(6):655-60. [Medline].

  18. Harel Z, Biro FM, Kottenhahn RK, Rosenthal SL. Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents. Am J Obstet Gynecol. Apr 1996;174(4):1335-8. [Medline].

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