eMedicine Specialties > Emergency Medicine > Obstetrics & Gynecology

Pelvic Inflammatory Disease: Follow-up

Author: Iris Reyes, MD, Advisory Dean; Director of Quality Improvement, Associate Professor, Department of Emergency Medicine, University of Pennsylvania
Coauthor(s): Ritu Kumar, MD, Resident, Department of Emergency Medicine, Hospital of the University of Pennsylvania; Stephanie Abbuhl, MD, Vice Chair, Associate Professor, Department of Emergency Medicine, University of Pennsylvania School of Medicine; Attending Physician in Emergency Services, Hospital of the University of Pennsylvania
Contributor Information and Disclosures

Updated: Feb 4, 2009

Follow-up

Further Inpatient Care

  • Clinical improvement should occur within 3 days of initiating therapy.
  • Consider further diagnostic tests, laparoscopy, or both if symptoms do not improve or worsen.
  • Surgical intervention may be indicated in patients with an enlarging pelvic mass despite medical therapy, intraperitoneal bleeding secondary to erosion into a vessel, or abscess rupture.
  • Remove IUDs following institution of antibiotics.

Further Outpatient Care

  • Patients should continue oral antibiotics for a full 2 weeks.
  • Follow-up is suggested in 3 days to monitor clinical improvement.
  • Sexual abstinence is advised until cure is achieved.
  • Treatment of sexual contacts is essential to prevent reinfection.
  • The CDC recommends the treatment of partners who have had sex with the patient during the 60 days preceding onset of symptoms.

Transfer

  • Transfer is advised only if a patient is stable and only if the hospital is incapable of managing acutely ill patients with gynecological emergencies.

Deterrence/Prevention

  • All patients should routinely receive sexual counseling, including advice to practice safe sex with the use of condoms. Other areas of discussion include limiting the number of sexual partners and avoiding contact with high-risk partners. Adolescents should be advised to delay the onset of sexual activity until the age of 16 years or older, as they are at an increased risk for pelvic inflammatory disease.
  • Barrier contraceptives (eg, diaphragms with spermicidal agents) and oral contraceptives are thought to reduce the risk for developing pelvic inflammatory disease.
  • Intrauterine devices (IUDs) predispose patients to pelvic inflammatory disease, predominantly during the first few months after insertion.
  • Frequent vaginal douching was considered to be a risk factor for pelvic inflammatory disease, but recent studies reveal no clear association.4

Complications

  • Ectopic pregnancy is 6 times more likely in women who have had pelvic inflammatory disease than in those who have not.
  • Tubal damage and scarring can result in infertility. One study demonstrated infertility in 8% of women after a single episode of pelvic inflammatory disease and in 40% of women after 3 or more episodes.
  • One investigator found chronic pelvic pain in up to 18% of women after pelvic inflammatory disease had resolved.

Prognosis

  • The prognosis is good if diagnosed and treated early.
  • A poor prognosis is related to late therapy and continued unsafe lifestyle.

Patient Education

Miscellaneous

Medicolegal Pitfalls

  • Failure to diagnose and treat patients with pelvic inflammatory disease (PID) in a timely manner
  • Failure to test for pregnancy and potentially to misdiagnose ectopic pregnancy
  • Failure to obtain a medication allergy history
  • Failure to test for syphilis
  • Failure to advise that sexual partners must be treated
 


More on Pelvic Inflammatory Disease

Overview: Pelvic Inflammatory Disease
Differential Diagnoses & Workup: Pelvic Inflammatory Disease
Treatment & Medication: Pelvic Inflammatory Disease
Follow-up: Pelvic Inflammatory Disease
References

References

  1. Molander P, Sjoberg J, Paavonen J, Cacciatore B. Transvaginal power Doppler findings in laparoscopically proven acute pelvic inflammatory disease. Ultrasound Obstet Gynecol. Mar 2001;17(3):233-8. [Medline].

  2. CDC. Sexually transmitted diseases treatment guidelines 2002. Centers for Disease Control and Prevention. MMWR Recomm Rep. May 10 2002;51(RR-6):1-78. [Medline].

  3. CDC. Update to CDC's sexually transmitted diseases treatment guidelines, 2006: Fluoroquinolones no longer recommended for treatment of gonococcal infections. MMWR Morb Mortal Wkly Rep. April 13 2007;56(14):332-336.

  4. Ness RB, Hillier SL, Kip KE, et al. Douching, pelvic inflammatory disease, and incident gonococcal and chlamydial genital infection in a cohort of high-risk women. Am J Epidemiol. Jan 15 2005;161(2):186-95. [Medline].

  5. CDC. 1998 guidelines for treatment of sexually transmitted diseases. Centers for Disease Control and Prevention. MMWR Morb Mortal Wkly Rep. Jan 23 1998;47(RR-1):1-111. [Medline].

  6. FDA. Center for Drug Evaluation and Research. Drugs to be discontinued. Available at www.fda.gov/cder/drug/shortages/#disc. Accessed May 2, 2007.

  7. Hillis SD, Joesoef R, Marchbanks PA. Delayed care of pelvic inflammatory disease as a risk factor for impaired fertility. Am J Obstet Gynecol. May 1993;168(5):1503-9. [Medline].

  8. Hollier LM, Workowski K. Treatment of sexually transmitted diseases in women. Obstet Gynecol Clin North Am. Dec 2003;30(4):751-75, vii-viii. [Medline].

  9. McCormack WM. Pelvic inflammatory disease. N Engl J Med. Jan 13 1994;330(2):115-9. [Medline].

  10. Meyers DS, Halvorson H, Luckhaupt S. Screening for chlamydial infection: an evidence update for the U.S. Preventive Services Task Force. Ann Intern Med. Jul 17 2007;147(2):135-42. [Medline].

  11. Ness RB, Hillier SL, Kip KE. Bacterial vaginosis and risk of pelvic inflammatory disease. Obstet Gynecol. Oct 2004;104(4):761-9. [Medline].

  12. Ness RB, Trautmann G, Richter HE, et al. Effectiveness of treatment strategies of some women with pelvic inflammatory disease: a randomized trial. Obstet Gynecol. Sep 2005;106(3):573-80. [Medline].

  13. Rice R, Schwartz D, Knapp J, et al. Pelvic inflammatory disease. In: Morse, Moreland, Holmes, eds. Atlas of Sexually Transmitted Diseases and AIDS. 1996:134-47.

  14. Sam JW, Jacobs JE, Birnbaum BA. Spectrum of CT findings in acute pyogenic pelvic inflammatory disease. Radiographics. Nov-Dec 2002;22(6):1327-34. [Medline].

  15. Soper DE. Pelvic inflammatory disease. Infect Dis Clin North Am. Dec 1994;8(4):821-40. [Medline].

  16. Suss AL, Homel P, Hammerschlag M, Bromberg K. Risk factors for pelvic inflammatory disease in inner-city adolescents. Sex Transm Dis. May 2000;27(5):289-91. [Medline].

  17. Walker CK, Wiesenfeld HC. Antibiotic therapy for acute pelvic inflammatory disease: the 2006 Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines. Clin Infect Dis. Apr 1 2007;44 Suppl 3:S111-22. [Medline].

  18. Westrom L, Joesoef R, Reynolds G, Hagdu A, Thompson SE. Pelvic inflammatory disease and fertility. A cohort study of 1,844 women with laparoscopically verified disease and 657 control women with normal laparoscopic results. Sex Transm Dis. Jul-Aug 1992;19(4):185-92. [Medline].

  19. Wiesenfeld HC, Sweet RL, Ness RB, Krohn MA, Amortegui AJ, Hillier SL. Comparison of acute and subclinical pelvic inflammatory disease. Sex Transm Dis. Jul 2005;32(7):400-5. [Medline].

Further Reading

Contributor Information and Disclosures

Author

Iris Reyes, MD, Advisory Dean; Director of Quality Improvement, Associate Professor, Department of Emergency Medicine, University of Pennsylvania
Iris Reyes, MD is a member of the following medical societies: American College of Emergency Physicians
Disclosure: Nothing to disclose.

Coauthor(s)

Ritu Kumar, MD, Resident, Department of Emergency Medicine, Hospital of the University of Pennsylvania
Ritu Kumar, MD is a member of the following medical societies: American Academy of Emergency Medicine, American Medical Student Association/Foundation, Emergency Medicine Residents Association, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Stephanie Abbuhl, MD, Vice Chair, Associate Professor, Department of Emergency Medicine, University of Pennsylvania School of Medicine; Attending Physician in Emergency Services, Hospital of the University of Pennsylvania
Stephanie Abbuhl, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Emergency Physicians, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Medical Editor

David S Howes, MD, Residency Program Director, Professor of Medicine, Section of Emergency Medicine, University of Chicago/Pritzker School of Medicine
David S Howes, MD is a member of the following medical societies: American College of Emergency Physicians, American College of Physicians-American Society of Internal Medicine, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Mark Zwanger, MD, MBA, Assistant Professor, Department of Emergency Medicine, Thomas Jefferson University
Mark Zwanger, MD, MBA is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and American Medical Association
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Pamela L Dyne, MD, Professor of Clinical Medicine/Emergency Medicine, David Geffen School of Medicine at UCLA; Attending Physician, Department of Emergency Medicine, Olive View-UCLA Medical Center
Pamela L Dyne, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

 
 
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