eMedicine Specialties > Emergency Medicine > Ophthalmology

Conjunctivitis: Follow-up

Author: Michael A Silverman, MD, Instructor of Emergency Medicine, The Johns Hopkins University School of Medicine; Chairman, Department of Emergency Medicine, Harbor Hospital
Coauthor(s): Edward Bessman, MD, Chairman, Department of Emergency Medicine, John Hopkins Bayview Medical Center; Assistant Professor, Department of Emergency Medicine, Johns Hopkins University
Contributor Information and Disclosures

Updated: Jun 1, 2009

Follow-up

Further Inpatient Care

  • Patients with gonorrheal infections, neonates with infections, and patients who are immunocompromised should be admitted for administration of IV antibiotics.

Further Outpatient Care

  • Refer patients to their primary care provider for follow-up in 2-3 days to ensure they are responding to treatment. Viral conjunctivitis usually is self-limited to 10-14 days, but symptoms may persist for as many as 6 weeks.

Inpatient & Outpatient Medications

  • Prescribe one of the previously mentioned antibiotics for discharged patients. For copious ocular secretions, patients may use frequent saline irrigation or artificial tears. Avoid eye patching.

Transfer

  • Manage simple conjunctivitis in the ED. Transfer may be appropriate for patients with complications from chronic or gonococcal conjunctivitis when an ophthalmologist is unavailable.

Deterrence/Prevention

  • Careful and frequent hand washing is necessary to reduce transmission from one eye to the other in the patient and from contacts.

Complications

  • Pneumonia can occur in 10-20% of infants with chlamydial conjunctivitis as many as 6 months later. Untreated chlamydial conjunctivitis in adults can lead to conjunctival scarring.
  • Penetration of the cornea can occur within 2 days in patients with untreated N gonorrhoeae.
  • Infections with N meningitidis may require systemic antibiotics to prevent meningitis.

Prognosis

  • Prognosis is good. Conjunctivitis typically is self-limited and without long-term complications.

Patient Education

  • Warm compresses and washing eyelids with diluted baby shampoo may speed resolution when blepharitis is an associated factor. Patients should not use eye makeup. Frequent hand washing is essential to prevent further transmission.
  • For excellent patient education resources, visit eMedicine's Eye and Vision Center. Also, see eMedicine's patient education article Pinkeye.

Miscellaneous

Medicolegal Pitfalls

  • Failure to recognize a gonococcal infection in someone with ocular and GU symptoms
  • Failure to recognize herpes simplex conjunctivitis and keratitis and prescribing corticosteroids
  • Failure to consider other causes in a patient with an acutely red eye (eg, iritis, uveitis, angle-closure glaucoma, ocular ischemic syndrome, penetrating or perforating ocular injury)

Special Concerns

  • During birth, risk of transmission of Gonococcus, Streptococcus, or Chlamydia to the fetus exists. Obtain cervical cultures if indicated.
  • Risk of chlamydial pneumonia exists. Any of the bacterial organisms that cause conjunctivitis, particularly in a premature infant, can lead to sepsis and death. Neonates are at risk for secondary meningitis, cellulitis, and septicemia, particularly if the conjunctivitis is caused by Escherichia coli, Staphylococcus aureus, or Haemophilus influenzae.
 


More on Conjunctivitis

Overview: Conjunctivitis
Differential Diagnoses & Workup: Conjunctivitis
Treatment & Medication: Conjunctivitis
Follow-up: Conjunctivitis
References

References

  1. [Guideline] American Academy of Ophthalmology Cornea/External Disease Panel. Preferred Practice Pattern Guidelines. Conjunctivitis. Sept 2008;[Full Text].

  2. US Food and Drug Administration. FDA News Release: FDA approves besivance to treat bacterial conjunctivitis. May 28, 2009. [Full Text].

  3. Schechter BA. Ketorolac tromethamine 0.4% as a treatment for allergic conjuctivitis. Expert Opin Drug Metab Toxicol. Apr 2008;4(4):507-11. [Medline].

  4. Abelson MB, Heller W, Shapiro AM, Si E, Hsu P, Bowman LM. Clinical Cure of Bacterial Conjunctivitis with Azithromycin 1%: Vehicle-Controlled, Double-Masked Clinical Trial. Am J Ophthalmol. Mar 27 2008;[Medline].

  5. Alessandrini EA. The case of the red eye. Pediatr Ann. Feb 2000;29(2):112-6. [Medline].

  6. Bersudsky V, Rehany U, Tendler Y. Diagnosis of chlamydial infection by direct enzyme-linked immunoassay and polymerase chain reaction in patients with acute follicular conjunctivitis. Graefes Arch Clin Exp Ophthalmol. Aug 1999;237(8):617-20. [Medline].

  7. Bertolini J, Pelucio M. The red eye. Emerg Med Clin North Am. Aug 1995;13(3):561-79. [Medline].

  8. Bessman ES. Nontraumatic eye disorders. In: Howell J, ed. Emergency Medicine. WB Saunders; 1997:609-625.

  9. Blumenthal MN, Schwartz RH, Kaiser H. Nedocromil sodium 2% ophthalmic solution for the treatment of ragweed pollen seasonal allergic conjunctivitis. Ocul Immunol Inflamm. Sep 2000;8(3):159-67. [Medline].

  10. Brook I. Ocular infections due to anaerobic bacteria in children. J Pediatr Ophthalmol Strabismus. Mar-Apr 2008;45(2):78-84. [Medline].

  11. Chisari G, Reibaldi M. Ciprofloxacin as treatment for conjunctivitis. J Chemother. Apr 2004;16(2):156-9. [Medline].

  12. Cochereau I, Meddeb-Ouertani A, Khairallah M, Amraoui A, Zaghloul K, Pop M, et al. 3-day treatment with azithromycin 1.5% eye drops versus 7-day treatment with tobramycin 0.3% for purulent bacterial conjunctivitis: multicentre, randomised and controlled trial in adults and children. Br J Ophthalmol. Apr 2007;91(4):465-9. [Medline].

  13. de Toledo AR, Chandler JW. Conjunctivitis of the newborn. Infect Dis Clin North Am. Dec 1992;6(4):807-13. [Medline].

  14. Fitch CP, Rapoza PA, Owens S. Epidemiology and diagnosis of acute conjunctivitis at an inner-city hospital. Ophthalmology. Aug 1989;96(8):1215-20. [Medline].

  15. Friedlaender MH. The current and future therapy of allergic conjunctivitis. Curr Opin Ophthalmol. Aug 1998;9(4):54-8. [Medline].

  16. Friedlaender MH, Howes J. A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. The Loteprednol Etabonate Giant Papillary Conjunctivitis Study Group I. Am J Ophthalmol. Apr 1997;123(4):455-64. [Medline].

  17. Gallenga PE, Lobefalo L, Colangelo L. Topical lomefloxacin 0.3% twice daily versus tobramycin 0.3% in acute bacterial conjunctivitis: A multicenter double-blind phase III study. Ophthalmologica. 1999;213(4):250-7. [Medline].

  18. Hammerschlag MR, Gelling M, Roblin PM. Treatment of neonatal chlamydial conjunctivitis with azithromycin. Pediatr Infect Dis J. Nov 1998;17(11):1049-50. [Medline].

  19. Joss JD, Craig TJ, R. Seasonal allergic conjunctivitis: overview and treatment update. J Am Osteopath Assoc. Jul 1999;99(7 Suppl):S13-8. [Medline].

  20. Kruse A, Thomsen RW, Hundborg HH. Diabetes and risk of acute infectious conjunctivitis--a population-based case-control study. Diabet Med. Apr 2006;23(4):393-7. [Medline].

  21. Leonardi A, Zafirakis P. Efficacy and comfort of olopatadine versus ketotifen ophthalmic solutions: a double-masked, environmental study of patient preference. Curr Med Res Opin. Aug 2004;20(8):1167-73. [Medline].

  22. Limberg MB. A review of bacterial keratitis and bacterial conjunctivitis. Am J Ophthalmol. Oct 1991;112(4 Suppl):2S-9S. [Medline].

  23. Litoff D, Belin MW, Catalano RA. Ocular infections and inflammation. In: Ocular Emergencies. Philadelphia: WB Saunders Co:1992:461-495. [Medline].

  24. Marangon FB, Miller D, Muallem MS, et al. Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis. Am J Ophthalmol. Mar 2004;137(3):453-8. [Medline].

  25. Morden NE, Berke EM. Topical fluoroquinolones for eye and ear. Am Fam Physician. Oct 15 2000;62(8):1870-6. [Medline].

  26. Morrow GL, Abbott RL. Conjunctivitis. Am Fam Physician. Feb 15 1998;57(4):735-46. [Medline].

  27. Newell FW. Conjunctivitis and keratitis. In: Ophthalmology: Principles and Concepts. St Louis: Mosby; 1992:225-245.

  28. Nichols J, Snyder RW. Topical nonsteroidal anti-inflammatory agents in ophthalmology. Curr Opin Ophthalmol. Aug 1998;9(4):40-4. [Medline].

  29. Porazinski AD, Donshik PC. Giant papillary conjunctivitis in frequent replacement contact lens wearers: a retrospective study. CLAO J. Jul 1999;25(3):142-7. [Medline].

  30. Rose GE. The giant fornix syndrome: an unrecognized cause of chronic, relapsing, grossly purulent conjunctivitis. Ophthalmology. Aug 2004;111(8):1539-45. [Medline].

  31. [Best Evidence] Sheikh A, Hurwitz B. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database Syst Rev. 2006;CD001211. [Medline].

  32. Steinert RF. Current therapy for bacterial keratitis and bacterial conjunctivitis. Am J Ophthalmol. Oct 1991;112(4 Suppl):10S-14S. [Medline].

  33. Wirbelauer C. Management of the red eye for the primary care physician. Am J Med. Apr 2006;119(4):302-6. [Medline].

Further Reading

Contributor Information and Disclosures

Author

Michael A Silverman, MD, Instructor of Emergency Medicine, The Johns Hopkins University School of Medicine; Chairman, Department of Emergency Medicine, Harbor Hospital
Michael A Silverman, MD is a member of the following medical societies: American College of Emergency Physicians, American College of Physician Executives, and American Medical Association
Disclosure: Nothing to disclose.

Coauthor(s)

Edward Bessman, MD, Chairman, Department of Emergency Medicine, John Hopkins Bayview Medical Center; Assistant Professor, Department of Emergency Medicine, Johns Hopkins University
Edward Bessman, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Medical Editor

William K Chiang, MD, Associate Professor, Department of Emergency Medicine, New York University School of Medicine; Chief of Service, Department of Emergency Medicine, Bellevue Hospital Center
William K Chiang, MD is a member of the following medical societies: American Academy of Clinical Toxicology, American College of Medical Toxicology, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Douglas Lavenburg, MD, Clinical Professor, Department of Emergency Medicine, Christiana Care Health Systems
Douglas Lavenburg, MD is a member of the following medical societies: American Society of Cataract and Refractive Surgery
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Barry E Brenner, MD, PhD, FACEP, Professor of Emergency Medicine, Professor of Internal Medicine, Program Director, Emergency Medicine, University Hospitals, Case Medical Center
Barry E Brenner, MD, PhD, FACEP is a member of the following medical societies: Alpha Omega Alpha, American Academy of Emergency Medicine, American College of Chest Physicians, American College of Emergency Physicians, American College of Physicians, American Heart Association, American Thoracic Society, Arkansas Medical Society, New York Academy of Medicine, New York Academy of Sciences, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

 
 
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