Iritis and Uveitis Workup

  • Author: Keith Tsang, MD; Chief Editor: Rick Kulkarni, MD   more...
 
Updated: May 4, 2011
 

Laboratory Studies

The workup should be tailored to the patient according to the history or to the signs and symptoms that point to a certain etiology.

Laboratory workup may not be necessary in certain situations.[6] In cases of mild, unilateral nongranulomatous uveitis in the setting of trauma, known systemic disease, or a history and physical not suggestive of systemic disease, laboratory studies are unlikely to be helpful.

If the history and the physical examination findings are unremarkable in the presence of bilateral uveitis, granulomatous uveitis, or recurrent uveitis, a nonspecific workup is indicated. These tests do not need to be conducted in the ED and may be ordered by the consulting ophthalmologist.[6]

  • CBC
  • Erythrocyte sedimentation rate (ESR)
  • Antinuclear antibody (ANA)
  • Rapid plasma reagin (RPR)
  • Venereal disease research laboratory (VDRL)
  • Purified protein derivative (PPD)
  • Lyme titer
  • HLA-B27
Next

Imaging Studies

A chest radiograph to assess for sarcoidosis or tuberculosis as the underlying cause of uveitis may be performed.

Previous
Proceed to Treatment & Management
 
 
Contributor Information and Disclosures
Author

Keith Tsang, MD  Resident Physician, Clinical Assistant Instructor, Department of Emergency Medicine, State University of New York Downstate, Kings County Hospital

Keith Tsang, MD is a member of the following medical societies: American College of Emergency Physicians, Emergency Medicine Residents Association, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Coauthor(s)

Richard H Sinert, DO  Associate Professor of Emergency Medicine, Clinical Assistant Professor of Medicine, Research Director, State University of New York College of Medicine; Consulting Staff, Department of Emergency Medicine, Kings County Hospital Center

Richard H Sinert, DO is a member of the following medical societies: American College of Physicians and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Eric M Kardon, MD, FACEP  Attending Emergency Physician, Georgia Emergency Medicine Specialists; Physician, Division of Emergency Medicine, Athens Regional Medical Center

Eric M Kardon, MD, FACEP is a member of the following medical societies: American College of Emergency Physicians

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Douglas Lavenburg, MD  Clinical Professor, Department of Emergency Medicine, Christiana Care Health Systems

Douglas Lavenburg, MD is a member of the following medical societies: American Society of Cataract and Refractive Surgery

Disclosure: Nothing to disclose.

John D Halamka, MD, MS  Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center

John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Chief Editor

Rick Kulkarni, MD  Attending Physician, Department of Emergency Medicine, Cambridge Health Alliance, Division of Emergency Medicine, Harvard Medical School

Rick Kulkarni, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Emergency Medicine, American College of Emergency Physicians, American Medical Association, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine

Disclosure: WebMD Salary Employment

Additional Contributors

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author, Kilbourn Gordon III, MD, to the development and writing of this article.

References

  1. Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. Sept 2005;140:509-16. [Medline].

  2. Yanoff and Duker. Uveitis and other intraocular inflammations. In: Ophthalmology. 3rd ed. Mosby; 2008.

  3. McCannel CA, Holland GN, Helm CJ, Cornell PJ, Winston JV, Rimmer TG. Causes of uveitis in the general practice of ophthalmology. UCLA Community-Based Uveitis Study Group. Am J Ophthalmol. Jan 1996;121(1):35-46. [Medline].

  4. Rodriguez A, Calonge M, Pedroza-Seres M, Akova YA, Messmer EM, D'Amico DJ, et al. Referral patterns of uveitis in a tertiary eye care center. Arch Ophthalmol. May 1996;114(5):593-9. [Medline].

  5. [Best Evidence] Islam N, Pavesio C. Uveitis (acute anterior). Clin Evid (Online). November 2009;04:705.

  6. Wills Eye Hospital. The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease. 5th ed. Philadelphia, Pa: Lippincott; 2008.

  7. Abad S, Seve P, Dhote R, Brezin AP. [Guidelines for the management of uveitis in internal medicine]. Rev Med Interne. Jun 2009;30(6):492-500. [Medline].

  8. Lyon F, Gale RP, Lightman S. Recent developments in the treatment of uveitis: an update. Expert Opin Investig Drugs. May 2009;18(5):609-16. [Medline].

  9. Lim LL, Smith JR, Rosenbaum JT. Retisert (Bausch & Lomb/Control Delivery Systems). Curr Opin Investig Drugs. Nov 2005;6(11):1159-67. [Medline].

  10. Mohammad DA, Sweet BV, Elner SG. Retisert: is the new advance in treatment of uveitis a good one?. Ann Pharmacother. Mar 2007;41(3):449-54. [Medline].

  11. Wirbelauer C. Management of the red eye for the primary care physician. Am J Med. Apr 2006;119(4):302-6. [Medline].

  12. Dunne JA, Travers JP. Topical steroids in anterior uveitis. Trans Opthalmol soc UK. 1979;99(4):481-4. [Medline].

  13. Foster CS, Alter G, DeBarge LR, Raizman MB, Crabb JL, Santos CI, et al. Efficacy and safety of rimexolone 1% ophthalmic suspension vs 1% prednisolone acetate in the treatment of uveitis. Am J Ophthalmol. Aug 1996;122(2):171-82. [Medline].

  14. Merck Manuals: Uveitis. Available at http://www.merck.com/mmhe/sec20/ch232/ch232a.html.

  15. Nishimoto JY. Iritis. How to recognize and manage a potentially sight-threatening disease. Postgrad Med. Feb 1996;99(2):255-7, 261-2. [Medline].

  16. Nussenblatt R, Whitcup S, Palestine A. Uveitis: Fundamentals and Clinical Practice. 2nd ed. St. Louis, Mo: Mosby; 1996.

  17. Tessler H. Classification and symptoms and signs of uveitis. In: Duane T, ed. Clinical Ophthalmology. New York, NY: Harper and Row; 1987:1-10.

 
Previous
Next
 
Anatomy of the eye.
Small stellate keratic precipitates with fine filaments in a patient with Fuchs heterochromic iridocyclitis.
Table 1. Classification of Uveitis
TypePrimary Site of InflammationIncludes
Anterior uveitisAnterior chamberIritis/iridocyclitis/anterior cyclitis
Intermediate uveitisVitreousPars planitis/posterior cyclitis/hyalitis
Posterior uveitisChoroidFocal, multifocal, or diffuse choroiditis/chorioretinitis/retinochoroiditis/retinitis/Neuroretinitis
PanuveitisAnterior chamber, vitreous, and/or choroid
Previous
Next
 
 
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.