Hordeolum and Stye in Emergency Medicine Medication
- Author: Michael J Bessette, MD, FACEP; Chief Editor: Rick Kulkarni, MD more...
Medication Summary
Start therapy for hordeolum with a topical treatment. Progress to systemic therapy only if signs and symptoms of severe infection are found.
Antibiotics
Class Summary
Topical antibiotics are useful for control of staphylococcal infections in eyelids and nares.
Bacitracin ophthalmic ointment (AK-Tracin)
Prevents transfer of mucopeptides into growing cell wall; inhibits bacterial cell wall synthesis.
Tobramycin ophthalmic solution or ointment (Tobrex, AKTob)
Interferes with bacterial protein synthesis by binding to 30S and 50S ribosomal subunits, which results in a defective bacterial cell membrane; available as solution, ointment, and lotion
Erythromycin (EES, E-Mycin, Ery-Tab)
First-choice treatment when systemic therapy is indicated; also indicated for treatment of infections caused by susceptible strains of microorganisms, including S aureus.
Dicloxacillin (Dycill, Dynapen)
For treatment of infections caused by penicillinase-producing staphylococci. May be used to initiate therapy when a staphylococcal infection is suspected.
Tetracycline (Sumycin)
Treats susceptible bacterial infections of both gram-positive and gram-negative organisms as well as infections caused by mycoplasmal, chlamydial, and rickettsial organisms; inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s) of susceptible bacteria
Cloxacillin (Cloxapen, Tegopen)
For treatment of infections caused by penicillinase-producing staphylococci. May be used to initiate therapy when a staphylococcal infection is suspected.
Hirunwiwatkul P, Wachirasereechai K. Effectiveness of combined antibiotic ophthalmic solution in the treatment of hordeolum after incision and curettage: a randomized, placebo-controlled trial: a pilot study. J Med Assoc Thai. May 2005;88(5):647-50. [Medline].
Barza M, Baum J. Ocular infections. Med Clin North Am. Jan 1983;67(1):131-52. [Medline].
Benton J, Karkanevatos A. Preseptal cellulitis due to Mycobacterium marinum. J Laryngol Otol. Jun 2007;121(6):606-8. [Medline].
Brafman AH. Styes: a curious chain. Br J Gen Pract. Dec 1992;42(365):537-8. [Medline].
Briner AM. Surgical treatment of a chalazion or hordeolum internum. Aust Fam Physician. Jun 1987;16(6):834-5. [Medline].
Briner AM. Treatment of common eyelid cysts. Aust Fam Physician. Jun 1987;16(6):828, 830. [Medline].
Diegel JT. Eyelid problems. Blepharitis, hordeola, and chalazia. Postgrad Med. Aug 1986;80(2):271-2. [Medline].
Jackson TL, Beun L. A prospective study of cost, patient satisfaction, and outcome of treatment of chalazion by medical and nursing staff. Br J Ophthalmol. Jul 2000;84(7):782-5. [Medline].
Lederman C, Miller M. Hordeola and chalazia. Pediatr Rev. Aug 1999;20(8):283-4. [Medline].
Olson MD. The common stye [published erratum appears in J Sch Health 1991 Mar;61(3):138]. J Sch Health. Feb 1991;61(2):95-7. [Medline].
Pavan-Langston D. Diagnosis and therapy of common eye infections: bacterial, viral, fungal. Compr Ther. May 1983;9(5):33-42. [Medline].
Raskin EM, Speaker MG, Laibson PR. Blepharitis. Infect Dis Clin North Am. Dec 1992;6(4):777-87. [Medline].

