Introduction
Background
One of the most challenging aspects of pediatric medicine is dealing with a child (usually <1 y of age) presenting with nonspecific symptoms, such as crying and irritability.
Because of the child's inability to localize complaints, these symptoms can indicate a spectrum of disease ranging from a benign process, such as colic, to a life-threatening illness, such as meningitis.1,2
Clinical
History
- The child's medical history, including surgeries, hospitalizations, illnesses, pregnancy complications, allergies, and birth events, should be obtained.
- Present medicines and recent illnesses should be reviewed.
- An explanation of events, including feeding habits, bowel movements, urination, fever, sick contacts, level of activity, degree and duration of concerns, and ability to be consoled, should be obtained.
Physical
- A complete and thorough physical examination should include the following: overall appearance, ability to be consoled, stability of vital signs, and temperature of the child.
- Other important aspects by system
- Rashes, perfusion, or bruising
- Head, ears, eyes, nose, and throat (HEENT) examination for anterior fontanel fullness, hydration status, scleral color, corneal abrasions, pupillary activity, retinal hemorrhages, otitis, pharyngitis, foreign bodies, or neck tenderness
- Dental examination for new tooth eruptions
- Chest evaluation for breath sounds and tachypnea
- Cardiovascular examination for murmurs, tachycardia, or arrhythmias
- Abdominal evaluation for tenderness and bowel activity, left lower quadrant (LLQ) masses suggestive of constipation, or vertical sausage mass consistent with intussusception
- Genitourinary examination for hernias, torsion (eg, a bluish mark within the scrotal contents indicating a torsed epididymal appendix, which is painful but usually self limited), or strangulations by hair tourniquets
- Rectal examination for blood or fissures
- Evaluation of extremities for focal tenderness, arthritis, or hair tourniquets
- Neurologic evaluation for overall activity level, responsiveness, and ability to be consoled
Causes
Causes of crying and irritability in the young child can vary greatly from relatively benign conditions, such as colic (a diagnosis of exclusion), to life-threatening conditions, such as meningitis or even abuse.3
The following is a partial listing, by systems, of potential causes of crying and irritability.
- Infections
- Meningitis
- Urinary tract infections
- Appendicitis
- Pneumonias
- Sepsis
- Otitis
- Gastroenteritis
- Local skin infections
- Trauma3
- Corneal abrasions
- Strangulation of extremities or genitalia (by hair)
- Fractures
- Abuse (including shaken baby syndrome)
- Burns
- Subdural hematomas
- Foreign bodies
- Dental/oral
- Aphthous ulcers
- Dental eruptions (with or without pericoronitis)
- Toxic or metabolic causes of irritability include any transient or persistent change in body chemistries.
- These can be endogenous or exogenous in origin.
- Anticholinergic adverse effects and antihistamine adverse effects in over-the-counter preparations
- Toxic exposures (eg, cocaine) and electrolyte abnormalities (eg, hypoglycemia, hypocalcemia, hyponatremia) are among a few of the potential causes.
- Genitourinary concerns include testicular torsion, hernias, and urinary tract infections.
- GI causes include life-threatening conditions (eg, intussusception, gastroenteritis) to more self-limiting conditions (eg, fissures, formula intolerance, colic).
- Cardiovascular concerns include supraventricular tachycardia or other arrhythmias.
- Other causes of crying and irritability are possible; however, a good system-by-system history and physical examination should help identify or rule out most concerns.
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References
Brazelton TB. Crying in infancy. Pediatrics. Apr 1962;29:579-88. [Medline].
Henretig FM. Crying and colic in early infancy. In: Fleisher GR, Ludwig S, eds. Textbook of Pediatric Emergency Medicine. 1993:144-6.
King WK, Kiesel EL, Simon HK. Child abuse fatalities: are we missing opportunities for intervention?. Pediatr Emerg Care. Apr 2006;22(4):211-4. [Medline].
Freedman SB, Al-Harthy N, Thull-Freedman J. The crying infant: diagnostic testing and frequency of serious underlying disease. Pediatrics. Mar 2009;123(3):841-8. [Medline].
Pawel B, Henretig F. Crying and colic in early infancy. In: Fleisher G, Ludwig S, eds. Textbook of Pediatric Emergency Medicine. 4th ed. Philadelphia, Pa: Lippincott Williams and Wilkins; 2000:193-195.
Further Reading
Keywords
crying baby, crying child, irritable child, irritable baby, inconsolable baby, broken bone, dislocation, causes, symptoms, treatment, child abuse, injury in child, colic, teething, trauma
Overview: Pediatrics, Crying Child