eMedicine Specialties > Emergency Medicine > Psychosocial
Anorexia Nervosa: Follow-up
Updated: Aug 21, 2008
Follow-up
Further Inpatient Care
- Patients with anorexia nervosa may require a medical admission if they are extremely ill, have cardiac dysrhythmias, or severe metabolic abnormalities.
- Most patients will either be admitted to psychiatric facilities both for refeeding and counseling or be managed on an outpatient basis.
Further Outpatient Care
- Close follow-up with the primary care physician is very important. Patients with anorexia nervosa should have their weight and electrolytes checked within a week of their emergency department visit.
- Outpatient psychiatric treatment should be arranged as soon as possible from either the emergency department or a primary care referral.
Complications
- Patients with anorexia nervosa are at risk for complications related to nutritional and electrolyte imbalances, as well as long-term social and interpersonal difficulties due to their disorder.
- Physiologic complications involve nearly every organ system.
- Fluid and electrolyte imbalances include hypokalemia, hyponatremia, hypochloremia, metabolic alkalosis, elevated BUN, decreased GFR, and ketonuria.
- Cardiovascular complications range from bradycardia, orthostatic hypotension, prolonged QT interval, low voltage, and mitral valve prolapse, to frank congestive heart failure and dysrhythmias.
- Gastrointestinal effects include constipation, bloating, early satiety, parotid gland hypertrophy, delayed gastric emptying, Mallory-Weiss tears, esophageal perforation, fatty liver infiltration, gallstones, and pancreatitis.
- Hematologic findings include anemia, leukopenia, thrombocytopenia, and impaired immunity.
- Endocrine problems due to starvation involve growth retardation, delayed puberty, amenorrhea, low T3 level, hypercortisolemia, and diabetes insipidus.
- Dermatologic complications include acrocyanosis, hypercarotenemia, brittle hair and nails, hair loss, lanugo, and pitting edema.
- Neurologically, patients may develop peripheral neuropathy, seizures, and cortical atrophy. Psychologically, patients are at risk for isolation, depression, and suicide in addition to their disordered thought patterns regarding food and weight.
- The process of refeeding must be undertaken slowly, with modest increases in metabolic demands to avoid heart failure and a "refeeding syndrome" including life-threatening dysrhythmias and hypophosphatemia. Ideal weight gain should occur at a rate of 1-2 lb per week.
Prognosis
- The prognosis for recovery from anorexia nervosa is multifactorial. Overall, the prognosis has not changed much over the past 50 years. In one large meta-analysis, 47% of patients fully recovered; 33% improved somewhat; and 20% developed chronic, relapsing anorexia.
- Patients with later age at onset of the disorder, binge-purge behavior, and concurrent mood disorders have a worse prognosis for full recovery.
Patient Education
- For excellent patient education resources, visit eMedicine's Eating Disorders Center and Women's Health Center. Also, see eMedicine's patient education articles Anorexia Nervosa and Amenorrhea.
- National Association of Anorexia Nervosa and Associated Disorders (ANAD)
- National Eating Disorders Association (NEDA)
- Anorexia Nervosa and Related Eating Disorders (ANRED)
Miscellaneous
Medicolegal Pitfalls
- As with all psychiatric and behavioral emergencies, care must be taken to prove and document competency upon discharge. Many patients with anorexia nervosa may have underlying psychopathology, which leaves them incapacitated during an anorexic crisis. If doubt remains, the patient must be admitted for more thorough psychiatric and physiologic monitoring or discharged in the care of a competent adult.
More on Anorexia Nervosa |
| Overview: Anorexia Nervosa |
| Differential Diagnoses & Workup: Anorexia Nervosa |
| Treatment & Medication: Anorexia Nervosa |
Follow-up: Anorexia Nervosa |
| References |
| « Previous Page |
References
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington DC: American Psychiatric Association; 1994:539-545.
Wilfley DE, Bishop ME, Wilson GT, et al. Classification of eating disorders: toward DSM-V. Int J Eat Disord. Nov 2007;40 Suppl:S123-9. [Medline].
Becker AE, Grinspoon SK, Klibanski A, et al. Eating disorders. N Engl J Med. Apr 8 1999;340(14):1092-8. [Medline].
Bochereau D, Clervoy P, Corcos M, et al. [Eating disorders. Anorexia nervosa in adolescents]. Presse Med. Jan 16 1999;28(2):89-99. [Medline].
Bowers WA, Ansher LS. The effectiveness of cognitive behavioral therapy on changing eating disorder symptoms and psychopathology of 32 anorexia nervosa patients at hospital discharge and one year follow-up. Ann Clin Psychiatry. Apr-Jun 2008;20(2):79-86. [Medline].
Coxson HO, Chan IH, Mayo JR, et al. Early emphysema in patients with anorexia nervosa. Am J Respir Crit Care Med. Oct 1 2004;170(7):748-52. [Medline].
Forman S. Eating Disorders: epidemiology, pathogenesis, and clinical features. Up to Date [online]. 2005.
Hoek HW, van Hoeken D. Review of the prevalence and incidence of eating disorders. Int J Eat Disord. Dec 2003;34(4):383-96. [Medline].
Kaplan H, Sadock B. Synopsis of Psychiatry. 8th ed. Williams and Wilkins; 1998:720-727.
Kaye W. Neurobiology of anorexia and bulimia nervosa. Physiol Behav. Apr 22 2008;94(1):121-35. [Medline].
Lavelle JM. Adolescent emergencies. In: Fleischer GR, Ludwig S, eds. Textbook of Pediatric Emergency Medicine. Philadelphia: Lippincott Williams & Wilkins; 1993:1503-1526.
Miller KK, Grinspoon SK, Ciampa J, et al. Medical findings in outpatients with anorexia nervosa. Arch Intern Med. Mar 14 2005;165(5):561-6. [Medline].
Nilsson EW, Gillberg C, Rastam M. Familial factors in anorexia nervosa: a community-based study. Compr Psychiatry. Nov-Dec 1998;39(6):392-9. [Medline].
Reinblatt SP, Redgrave GW, Guarda AS. Medication management of pediatric eating disorders. Int Rev Psychiatry. Apr 2008;20(2):183-8. [Medline].
Rosenblum J, Forman S. Evidence-based treatment of eating disorders. Curr Opin Pediatr. Aug 2002;14(4):379-83. [Medline].
Steinhausen HC. The outcome of anorexia nervosa in the 20th century. Am J Psychiatry. Aug 2002;159(8):1284-93. [Medline].
Stoving RK, Hangaard J, Hansen-Nord M, et al. A review of endocrine changes in anorexia nervosa. J Psychiatr Res. Mar-Apr 1999;33(2):139-52. [Medline].
Sylvester CJ, Forman SF. Clinical practice guidelines for treating restrictive eating disorder patients during medical hospitalization. Curr Opin Pediatr. Aug 2008;20(4):390-7. [Medline].
Vazquez M, Olivares JL, Fleta J, et al. Cardiac disorders in young women with anorexia nervosa. Rev Esp Cardiol. Jul 2003;56(7):669-73. [Medline].
Zimmerman M, Francione-Witt C, Chelminski I, Young D, Tortolani C. Problems applying the DSM-IV eating disorders diagnostic criteria in a general psychiatric outpatient practice. J Clin Psychiatry. Mar 2008;69(3):381-4. [Medline].
Further Reading
Keywords
anorexia, anorexia nervosa, eating disorder, self-starvation, binging, purging, malnutrition, severe weight loss, extreme weight loss, life-threatening weight loss, amenorrhea, intense fear of obesity, primary amenorrhea, secondary amenorrhea, denial of hunger, depression, obsessive-compulsive behavior, binge behavior, purge behavior, anxiety disorder, hypoglycemia, vitamin deficiencies, delayed puberty, anovulation, supraventricular dysrhythmias, ventricular dysrhythmias, long QT syndrome, bradycardia, orthostatic hypotension, shock, congestive heart failure, hypokalemia, hypochloremic alkalosis, hyperaldosteronism, gastric dilation, gastric rupture, dental enamel erosion, palatal trauma, esophagitis, Mallory Weiss lesions, diminished gag reflex, substance abuse
Follow-up: Anorexia Nervosa