Emergent Management of Anorexia Nervosa Treatment & Management

  • Author: Ron D Waldrop, MD, MS, FAAP, FACEP, FACPE; Chief Editor: Barry E Brenner, MD, PhD, FACEP   more...
 
Updated: Jun 17, 2011
 

Approach Considerations

Metabolic abnormalities in patients with anorexia nervosa should be corrected as needed, with oral or parenteral treatment depending on the patient's mental status and decision to cooperate. Hospital admission may be indicated for patients who are extremely ill, have cardiac dysrhythmias, or have severe metabolic abnormalities. Most patients will be admitted to medical facilities for re-feeding, referred to psychiatric facilities and counseling if medically stable, or be managed on an outpatient basis.

It is not necessary to begin parenteral nutrition in the emergency department; the focus should be on stabilization of acute abnormalities while an inpatient team including nutrition specialists can determine a re-feeding schedule. The process of re-feeding must be undertaken slowly, with modest increases in metabolic demands to avoid heart failure and a "re-feeding syndrome" that includes life-threatening dysrhythmias and hypophosphatemia. Ideal weight gain should occur at a rate of 1-2 lbs per week.

Inpatient treatment in a medical facility should always include psychiatric consultation for ongoing treatment of the underlying anorexia nervosa while addressing the acute medical complications of malnutrition.

Acute pharmacologic treatment of anorexia nervosa is rarely required, and cases of extreme altered mental status or psychosis should prompt a search for underlying profound metabolic disorders. The psychopharmacology of anorexia nervosa should be determined in consultation with a psychiatrist.

As with all psychiatric and behavioral emergencies, care must be taken to prove and document competency upon discharge. Many patients with anorexia nervosa may have additional psychopathology, which leaves them incapacitated during an anorexic crisis. If doubt remains, the patient must be admitted for more thorough psychiatric and physiologic monitoring or discharged in the care of a competent caretaker.

Transfer to an inpatient psychiatric facility may be the disposition for patients who are medically safe for discharge but who require aggressive inpatient psychiatric treatment of their disorder.

Next

Indications for Hospital Admission

Life-threatening or potentially lethal abnormalities require admission. Indications for hospitalization include the following:

  • Bradycardia or other cardiac dysrhythmias
  • Severe electrolyte abnormalities, especially of potassium, sodium, and phosphorus levels
  • Altered mental status or suicidality
  • Extremely low body weight
  • Failure of outpatient treatment
Previous
Next

Consultations

Most cases of anorexia nervosa encountered in the emergency department will be appropriate for outpatient management if close, planned follow-up is arranged prior to discharge. Consultation with the pediatrician or primary care physician is necessary to arrange follow-up. Urgency of follow-up depends on the patient's condition and how soon the laboratory study results will need to be reevaluated.

Psychiatric consultation in the emergency department should be considered for patients expressing suicidality, psychosis, or severely disordered thinking. Outpatient psychiatric follow-up is necessary and may be arranged either from the ED or by the primary care provider.

Previous
Next

Long-Term Monitoring

Close follow-up with the primary care physician is very important.

Patients with anorexia nervosa should have their weight and electrolytes checked within a week of their emergency department visit.

Outpatient psychiatric treatment should be arranged as soon as possible from either the emergency department or a primary care referral.

Previous
Proceed to Medication
 
 
Contributor Information and Disclosures
Author

Ron D Waldrop, MD, MS, FAAP, FACEP, FACPE  Emergency Physician, Commonwealth Emergency Physicians; Director of Pediatric Quality Care Management, Inova Loudoun Hospital; Adjunct Clinical Professor, Georgetown University School of Medicine

Ron D Waldrop, MD, MS, FAAP, FACEP, FACPE is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Coauthor(s)

Tracy A Cushing, MD, MPH, FACEP, FAWM  Assistant Professor, Department of Emergency Medicine, University of Colorado School of Medicine; Attending Physician, Denver Health Medical Center

Tracy A Cushing, MD, MPH, FACEP, FAWM is a member of the following medical societies: American College of Emergency Physicians, Society for Academic Emergency Medicine, and Wilderness Medical Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Edward Bessman, MD  Chairman, Department of Emergency Medicine, John Hopkins Bayview Medical Center; Assistant Professor, Department of Emergency Medicine, Johns Hopkins University School of Medicine

Edward Bessman, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Robert Harwood, MD, MPH, FACEP, FAAEM  Program Director, Department of Emergency Medicine, Advocate Christ Medical Center; Assistant Professor, Department of Emergency Medicine, University of Illinois at Chicago College of Medicine

Robert Harwood, MD, MPH, FACEP, FAAEM is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, American Medical Association, Council of Emergency Medicine Residency Directors, Phi Beta Kappa, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Chief Editor

Barry E Brenner, MD, PhD, FACEP  Professor of Emergency Medicine, Professor of Internal Medicine, Program Director, Emergency Medicine, Case Medical Center, University Hospitals, Case Western Reserve University School of Medicine

Barry E Brenner, MD, PhD, FACEP is a member of the following medical societies: Alpha Omega Alpha, American Academy of Emergency Medicine, American College of Chest Physicians, American College of Emergency Physicians, American College of Physicians, American Heart Association, American Thoracic Society, Arkansas Medical Society, New York Academy of Medicine, New York Academy of Sciences, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Acknowledgments

The authors and editors of Medscape Reference gratefully acknowledge the contributions of Siobhan O'Herron, MD,to the development and writing of the source article.

References
  1. Kaplan H, Sadock B. Fleischer GR, Ludwig S, eds. Synopsis of Psychiatry. 8th ed. Williams and Wilkins; 1998:720-727.

  2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition. Washington DC: American Psychiatric Association; 1994:539-545.

  3. Wilfley DE, Bishop ME, Wilson GT, Agras WS. Classification of eating disorders: toward DSM-V. Int J Eat Disord. Nov 2007;40 Suppl:S123-9. [Medline].

  4. Zimmerman M, Francione-Witt C, Chelminski I, Young D, Tortolani C. Problems applying the DSM-IV eating disorders diagnostic criteria in a general psychiatric outpatient practice. J Clin Psychiatry. Mar 2008;69(3):381-4. [Medline].

  5. Forman S. Eating Disorders: epidemiology, pathogenesis, and clinical features. Up to Date [online]. 2005.

  6. Hoek HW, van Hoeken D. Review of the prevalence and incidence of eating disorders. Int J Eat Disord. Dec 2003;34(4):383-96. [Medline].

  7. Treasure J, Claudino AM, Zucker N. Eating disorders. Lancet. Feb 13 2010;375(9714):583-93. [Medline].

  8. Nilsson EW, Gillberg C, Råstam M. Familial factors in anorexia nervosa: a community-based study. Compr Psychiatry. Nov-Dec 1998;39(6):392-9. [Medline].

  9. Kaye W. Neurobiology of anorexia and bulimia nervosa. Physiol Behav. Apr 22 2008;94(1):121-35. [Medline]. [Full Text].

  10. Sohlberg S, Strober M. Personality in Anorexia nervosa: an update and a theoretical integration. Acta Psychiatr Scand Suppl. 1994;378:1-15. [Medline].

  11. Stoving RK, Hangaard J, Hansen-Nord M, Hagen C. A review of endocrine changes in anorexia nervosa. J Psychiatr Res. Mar-Apr 1999;33(2):139-52. [Medline].

  12. Macias-Robles MD, Perez-Clemente AM, Macia-Bobes C, Alvarez-Rueda MA, Pozo-Nuevo S. Prolonged QT interval in a man with anorexia nervosa. Int Arch Med. Jul 31 2009;2(1):23. [Medline]. [Full Text].

  13. Vazquez M, Olivares JL, Fleta J, Lacambra I, Gonzalez M. [Cardiac disorders in young women with anorexia nervosa]. Rev Esp Cardiol. Jul 2003;56(7):669-73. [Medline].

  14. Morse JL, Safdar B. Acute tension pneumothorax and tension pneumoperitoneum in a patient with anorexia nervosa. J Emerg Med. Apr 2010;38(3):e13-6. [Medline].

  15. Verhoef PA, Rampal A. Unique challenges for appropriate management of a 16-year-old girl with superior mesenteric artery syndrome as a result of anorexia nervosa: a case report. J Med Case Reports. Nov 16 2009;3:127. [Medline]. [Full Text].

  16. Becker AE, Grinspoon SK, Klibanski A, Herzog DB. Eating disorders. N Engl J Med. Apr 8 1999;340(14):1092-8. [Medline].

  17. Bochereau D, Clervoy P, Corcos M, Girardon N. [Eating disorders. Anorexia nervosa in adolescents]. Presse Med. Jan 16 1999;28(2):89-99. [Medline].

  18. Lavelle JM. Adolescent emergencies. In: Fleischer GR, Ludwig S, eds. Textbook of Pediatric Emergency Medicine. Philadelphia: Lippincott Williams & Wilkins; 1993:1503-1526.

  19. Bowers WA, Ansher LS. The effectiveness of cognitive behavioral therapy on changing eating disorder symptoms and psychopathology of 32 anorexia nervosa patients at hospital discharge and one year follow-up. Ann Clin Psychiatry. Apr-Jun 2008;20(2):79-86. [Medline].

  20. Steinhausen HC. The outcome of anorexia nervosa in the 20th century. Am J Psychiatry. Aug 2002;159(8):1284-93. [Medline].

  21. Crow SJ, Peterson CB, Swanson SA, Raymond NC, Specker S, Eckert ED. Increased mortality in bulimia nervosa and other eating disorders. Am J Psychiatry. Dec 2009;166(12):1342-6. [Medline].

  22. Sylvester CJ, Forman SF. Clinical practice guidelines for treating restrictive eating disorder patients during medical hospitalization. Curr Opin Pediatr. Aug 2008;20(4):390-7. [Medline].

  23. Altinyazar V, Kiylioglu N, Salkin G. Anorexia Nervosa and Wernicke Korsakoff's Syndrome: Atypical Presentation by Acute Psychosis. Int J Eat Disord. 2010.

  24. Miller KK, Grinspoon SK, Ciampa J, Hier J, Herzog D, Klibanski A. Medical findings in outpatients with anorexia nervosa. Arch Intern Med. Mar 14 2005;165(5):561-6. [Medline].

  25. Coxson HO, Chan IH, Mayo JR, Hlynsky J, Nakano Y, Birmingham CL. Early emphysema in patients with anorexia nervosa. Am J Respir Crit Care Med. Oct 1 2004;170(7):748-52. [Medline].

  26. Reinblatt SP, Redgrave GW, Guarda AS. Medication management of pediatric eating disorders. Int Rev Psychiatry. Apr 2008;20(2):183-8. [Medline].

  27. Rosenblum J, Forman S. Evidence-based treatment of eating disorders. Curr Opin Pediatr. Aug 2002;14(4):379-83. [Medline].

Previous
Next
 
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.