Follow-up
Further Outpatient Care
- In general, the patient may be discharged from the hospital if the peak expiratory flow (PEF) or the patient's personal best expiratory flow rate is 70% or more of predicted rate and if symptoms are minimal or absent. It is important during therapy that the patient's predicted PEFR is based on the gender, height, and age of the patient.
- Patients who have mild symptoms but have PEF of 50-69% of predicted or personal best could be considered for discharge if high-risk factors for relapse are not present. However, patients with PEF of 50-69% of predicted or personal best who may be unable to obtain medications for psychiatric or socioeconomic reasons have a lower admission threshold.
- Consider referral to an asthma specialist, as consultation and guidance have been shown to reduce the risk of future ED visits.
- ED staff should emphasize the importance of follow-up care after the ED visit for education about asthma and for initiation of environmental and pharmacologic interventions that can prevent future exacerbations and otherwise improve the patient's quality of life.
- Asthma education efforts after the ED visit usually can address a much larger number of issues than during the actual ED visit, when teaching needs to be extremely focused. Nevertheless, a preventive message should be delivered at all clinical encounters.
- At the more comprehensive post-ED visit session—in the allergist or pulmonologist office, or in special asthma programs set up by the ED or primary care practice—potential topics include asthma triggers (viral URIs, allergens such as cats), the proper use of inhaler medications, the use of spacers and value of oral rinsing after use of inhaled corticosteroids, and the significance of nocturnal exacerbations (10-fold more asthmatics are intubated at night). The patient should have a written action plan telling him or her what to do in response to certain symptoms or certain PEF values. Many educational sessions are based on the action plan and its use.
- ED staff also should emphasize the importance of not running out of medications or even running low on medications (note MDI only reliable for number of actuations listed on the canister; almost no patient counts the number of actuations, and floating techniques for canister are unreliable and no longer recommended). Tell the patient to keep an extra canister, especially of inhaled beta-agonists.
- In general, discharging a patient on effective inhaled corticosteroids (eg, medium-dose budesonide or fluticasone) is beneficial. Most ED patients will not follow up with a primary care provider (PCP) in the weeks after the ED visit and will not receive inhaled corticosteroids unless it is started at ED or hospital discharge.
Complications
- Complications of severe asthma include the following:
- Respiratory distress/arrest
- Death
Prognosis
- The prognosis is excellent if compliant with proper therapies.
- Risk factors for death from asthma include labile asthma, history of more than 3 ED visits or more than 2 hospitalizations, either ICU admission or endotracheal intubation within the past year, recent withdrawal from corticosteroids, current use of systemic corticosteroids, comorbid conditions (eg, heart disease, psychiatric disease, drug abuse), and concomitant adverse socioeconomic conditions.
Patient Education
- For excellent patient education resources, see eMedicine's Asthma Center. Also, visit eMedicine's patient education articles Asthma, Asthma FAQs, Asthma in Children, and Understanding Asthma Medications.
Miscellaneous
Medicolegal Pitfalls
- Presumptive diagnosis of asthma, especially new onset - Asthma may actually be a misdiagnosis and may reflect CHF, myocarditis, multiple pulmonary emboli, surreptitious vocal cord dysfunction, or panic disorder/hyperventilation.
- Not obtaining PEFR on a patient and discharging the patient below 60-70% of his or her predicted
More on Asthma |
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References
Ginde AA, Espinola JA, Camargo CA Jr. Improved overall trends but persistent racial disparities in emergency department visits for acute asthma, 1993-2005. J Allergy Clin Immunol. Aug 2008;122(2):313-8. [Medline].
Epidemiology and Statistics Unit. Trends in asthma morbidity and mortality. January 2009. New York. American Lung Association. Available at http://www.lungusa.org/atf/cf/%7B7a8d42c2-fcca-4604-8ade-7f5d5e762256%7D/ASTHMA%20JAN%202009.PDF.
Brenner BE, Holmes TM, Mazal B, Camargo CA Jr. Relation between phase of the menstrual cycle and asthma presentations in the emergency department. Thorax. Oct 2005;60(10):806-9. [Medline].
Zimmerman JL, Woodruff PG, Clark S, Camargo CA. Relation between phase of menstrual cycle and emergency department visits for acute asthma. Am J Respir Crit Care Med. Aug 2000;162(2 Pt 1):512-5. [Medline].
Workgroup on EMS Management of Asthma Exacerbations. A model protocol for emergency medical services management of asthma exacerbations. Prehosp Emerg Care. Oct-Dec 2006;10(4):418-29. [Medline].
[Guideline] National Asthma Education and Prevention Program. Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma - Update on Selected Topics 2002. June 2003. [Full Text].
[Guideline] National Asthma Education and Prevention Program. Guidelines for the Diagnosis and Management of Asthma (EPR-3). July 2007. [Full Text].
Starobin D, Bolotinsky L, Or J, Fink G, Shtoeger Z. Efficacy of nebulized fluticasone propionate in adult patients admitted to the emergency department due to bronchial asthma attack. Isr Med Assoc J. Aug-Sep 2008;10(8-9):568-71. [Medline].
[Guideline] Rodriguez-Trigo G, Plaza V, Picado C, Sanchis J. [Management according to the Global Initiative for Asthma guidelines of patients with near-fatal asthma reduces morbidity and mortality]. Arch Bronconeumol. Apr 2008;44(4):192-6. [Medline].
[Guideline] Reddel HK, Taylor DR, Bateman ED, et al. An official American Thoracic Society/european Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med. Jul 1 2009;180(1):59-99. [Medline].
Alvarez GG, Schulzer M, Jung D, Fitzgerald JM. A systematic review of risk factors associated with near-fatal and fatal asthma. Can Respir J. Jul-Aug 2005;12(5):265-70. [Medline].
Appel D, Karpel JP, Sherman M. Epinephrine improves expiratory flow rates in patients with asthma who do not respond to inhaled metaproterenol sulfate. J Allergy Clin Immunol. Jul 1989;84(1):90-8. [Medline].
Banerji A, Clark S, Afilalo M, et al. Prospective multicenter study of acute asthma in younger versus older adults presenting to the emergency department. J Am Geriatr Soc. Jan 2006;54(1):48-55. [Medline].
[Best Evidence] Baren JM, Boudreaux ED, Brenner BE, et al. Randomized controlled trial of emergency department interventions to improve primary care follow-up for patients with acute asthma. Chest. Feb 2006;129(2):257-65. [Medline].
Boychuk RB, Yamamoto LG, DeMesa CJ, Kiyabu KM. Correlation of initial emergency department pulse oximetry values in asthma severity classes (steps) with the risk of hospitalization. Am J Emerg Med. Jan 2006;24(1):48-52. [Medline].
Brenner BE, Chavda KK, Karakurum MB, et al. Circadian differences among 4,096 emergency department patients with acute asthma. Crit Care Med. Jun 2001;29(6):1124-9. [Medline].
Browne GJ, Penna AS, Phung X, Soo M. Randomised trial of intravenous salbutamol in early management of acute severe asthma in children. Lancet. Feb 1 1997;349(9048):301-5. [Medline].
Camargo CA, Smithline HA, Malice MP, et al. A randomized controlled trial of intravenous montelukast in acute asthma. Am J Respir Crit Care Med. Feb 15 2003;167(4):528-33. [Medline].
Camargo CA, Spooner CH, Rowe BH. Continuous versus intermittent beta-agonists in the treatment of acute asthma. Cochrane Database Syst Rev. 2003;CD001115. [Medline].
Cates CC, Bara A, Crilly JA, Rowe BH. Holding chambers versus nebulisers for beta-agonist treatment of acute asthma. Cochrane Database Syst Rev. 2003;CD000052. [Medline].
Chapman KR, Verbeek PR, White JG, et al. Effect of a short course of prednisone in the prevention of early relapse after the emergency room treatment of acute asthma. N Engl J Med. Mar 21 1991;324(12):788-94. [Medline].
Cheuk DKL, Chau TCH, Lee SL. A meta-analysis on intravenous magnesium sulfate for treating acute asthma. Arch Dis Child. 2005;90:74-7.
Cydulka RK, Emerman CL, Schreiber D, et al. Acute asthma among pregnant women presenting to the emergency department. Am J Respir Crit Care Med. Sep 1999;160(3):887-92. [Medline].
Edmonds ML, Camargo CA, Pollack CV, Rowe BH. Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. Cochrane Database Syst Rev. 2000;CD002308. [Medline].
Edmonds ML, Camargo CA, Saunders LD, et al. Inhaled steroids in acute asthma following emergency department discharge. Cochrane Database Syst Rev. 2000;CD002316. [Medline].
Emerman CL, Cydulka RK, Crain EF, et al. Prospective multicenter study of relapse after treatment for acute asthma among children presenting to the emergency department. J Pediatr. Mar 2001;138(3):318-24. [Medline].
Emerman CL, Woodruff PG, Cydulka RK, et al. Prospective multicenter study of relapse following treatment for acute asthma among adults presenting to the emergency department. MARC investigators. Multicenter Asthma Research Collaboration. Chest. Apr 1999;115(4):919-27. [Medline].
Emond SD, Camargo CA, Nowak RM. 1997 National Asthma Education and Prevention Program guidelines: a practical summary for emergency physicians. Ann Emerg Med. May 1998;31(5):579-89. [Medline].
Gibbs MA, Camargo CA, Rowe BH, Silverman RA. State of the art: therapeutic controversies in severe acute asthma. Acad Emerg Med. Jul 2000;7(7):800-15. [Medline].
Gorelick MH, Stevens MW, Schultz T, Scribano PV. Difficulty in obtaining peak expiratory flow measurements in children with acute asthma. Pediatr Emerg Care. Jan 2004;20(1):22-6. [Medline].
Griswold SK, Nordstrom CR, Clark S, et al. Asthma exacerbations in North American adults: who are the "frequent fliers" in the emergency department?. Chest. May 2005;127(5):1579-86. [Medline].
Gupta VK, Cheifetz IM. Heliox administration in the pediatric intensive care unit: an evidence-based review. Pediatr Crit Care Med. Mar 2005;6(2):204-11. [Medline].
Hess DR, Acosta FL, Ritz RH, et al. The effect of heliox on nebulizer function using a beta-agonist bronchodilator. Chest. Jan 1999;115(1):184-9. [Medline].
Keahey L, Bulloch B, Becker AB, et al. Initial oxygen saturation as a predictor of admission in children presenting to the emergency department with acute asthma. Ann Emerg Med. Sep 2002;40(3):300-7. [Medline].
Kelly AM, Kyle E, McAlpine R. Venous pCO(2) and pH can be used to screen for significant hypercarbia in emergency patients with acute respiratory disease. J Emerg Med. Jan 2002;22(1):15-9. [Medline].
Kikuchi Y, Okabe S, Tamura G, et al. Chemosensitivity and perception of dyspnea in patients with a history of near-fatal asthma. N Engl J Med. May 12 1994;330(19):1329-34. [Medline].
Lahn M, Bijur P, Gallagher EJ. Randomized clinical trial of intramuscular vs oral methylprednisolone in the treatment of asthma exacerbations following discharge from an emergency department. Chest. Aug 2004;126(2):362-8. [Medline].
Lee DL, Hsu CW, Lee H, et al. Beneficial effects of albuterol therapy driven by heliox versus by oxygen in severe asthma exacerbation. Acad Emerg Med. Sep 2005;12(9):820-7. [Medline].
Mannino DM, Homa DM, Akinbami LJ, et al. Surveillance for asthma--United States, 1980-1999. MMWR Surveill Summ. Mar 29 2002;51(1):1-13. [Medline].
Martin TG, Elenbaas RM, Pingleton SH. Use of peak expiratory flow rates to eliminate unnecessary arterial blood gases in acute asthma. Ann Emerg Med. Feb 1982;11(2):70-3. [Medline].
McFadden ER, Kiser R, DeGroot WJ. Acute bronchial asthma: Relations between clinical and physiologic manifestations. New Engl J Med. 1973;288:221-225. [Medline].
[Best Evidence] Mitra A, Bassler D, Goodman K, et al. Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators. Cochrane Database Syst Rev. 2005;CD001276. [Medline].
Nowak RM, Pensler MI, Sarkar DD, et al. Comparison of peak expiratory flow and FEV1 admission criteria for acute bronchial asthma. Ann Emerg Med. Feb 1982;11(2):64-9. [Medline].
Parameswaran K, Belda J, Rowe BH. Addition of intravenous aminophylline to beta2-agonists in adults with acute asthma. Cochrane Database Syst Rev. 2000;CD002742. [Medline].
Plotnick LH, Ducharme FM. Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children. Cochrane Database Syst Rev. 2000;CD000060. [Medline].
Pollack CV, Pollack ES, Baren JM, et al. A prospective multicenter study of patient factors associated with hospital admission from the emergency department among children with acute asthma. Arch Pediatr Adolesc Med. Sep 2002;156(9):934-40. [Medline].
Radeos MS, Camargo CA. Predicted peak expiratory flow: differences across formulae in the literature. Am J Emerg Med. Nov 2004;22(7):516-21. [Medline].
Rowe BH, Bretzlaff JA, Bourdon C, et al. Magnesium sulfate treatment for treating exacerbations of acute asthma in the emergency department. Cochrane Database Syst Rev. 2000;2:CD001490.
Rowe BH, Camargo CA. The use of magnesium sulfate in acute asthma: rapid uptake of evidence in North American emergency departments. J Allergy Clin Immunol. Jan 2006;117(1):53-8. [Medline].
Rowe BH, Edmonds ML, Spooner CH, et al. Corticosteroid therapy for acute asthma. Respir Med. Apr 2004;98(4):275-84. [Medline].
Scarfone RJ, Fuchs SM, Nager AL, et al. Controlled trial of oral prednisone in the emergency department treatment of children with acute asthma. Pediatrics. Oct 1993;92(4):513-8. [Medline].
Singer AJ, Camargo CA, Lampell M, et al. A call for expanding the role of the emergency physician in the care of patients with asthma. Ann Emerg Med. Mar 2005;45(3):295-8. [Medline].
Singh AK, Cydulka RK, Stahmer SA, et al. Sex differences among adults presenting to the emergency department with acute asthma. Multicenter Asthma Research Collaboration Investigators. Arch Intern Med. Jun 14 1999;159(11):1237-43. [Medline].
[Best Evidence] Teach SJ, Crain EF, Quint DM, et al. Improved asthma outcomes in a high-morbidity pediatric population: results of an emergency department-based randomized clinical trial. Arch Pediatr Adolesc Med. May 2006;160(5):535-41. [Medline].
Travers A, Jones AP, Kelly K, et al. Intravenous beta2-agonists for acute asthma in the emergency department. Cochrane Database Syst Rev. 2001;CD002988. [Medline].
Tuxen DV. Permissive hypercapnic ventilation. Am J Respir Crit Care Med. Sep 1994;150(3):870-4. [Medline].
Weber EJ, Silverman RA, Callaham ML, et al. A prospective multicenter study of factors associated with hospital admission among adults with acute asthma. Am J Med. Oct 1 2002;113(5):371-8. [Medline].
Further Reading
Keywords
asthma, asthma attack, asthma symptoms, asthma treatment, asthma evaluation, asthma assessment, asthma causes, airway obstruction, asthma management, asthma exacerbation, airway inflammation, bronchial asthma, asthma triggers, dyspnea, wheezing, shortness of breath, asthmatic, reactive airway disease, wheeze, bronchiolitis, acute asthma, asthma prevention, allergies, bronchial airways, bronchial airway narrowing, inflammation of the bronchi, bronchial smooth muscle contraction, airway narrowing, noisy breathing, difficult breathing, difficulty breathing, inhalers, lung disease
Follow-up: Asthma