Laboratory Studies
- Gonococcal cultures of the urethra or cervix, rectum, and pharynx are appropriate if gonococcal tenosynovitis is suspected. One of these cultures is positive in approximately 80% of patients.
- CBC count with differential is appropriate if an infectious etiology is suspected.
- Erythrocyte sedimentation rate (ESR) is appropriate if an infectious etiology is suspected.
- Transiently elevated liver function studies have been described with disseminated gonococcal infection.
Imaging Studies
- Radiographs are low yield, unless a retained radiopaque soft tissue foreign body is suspected or if they are needed to rule out a fracture.
- MRI has proven accurate in assisting the diagnosis of tenosynovitis; however, it is expensive and generally unnecessary since the diagnosis is usually clinically evident.
Procedures
- Diagnostic arthrocentesis is indicated if joint effusion is present with tenosynovitis because most patients with disseminated gonococcal infection have coexistent septic arthritis.
- Sterile fluid is common with gonococcal arthritis; cultures are negative in 50% of patients.
- Most gonococcal arthritis is monoarticular; approximately 25% is polyarticular.
- Joint fluid glucose is usually normal.
- WBC counts are usually less than 50,000, and a Gram stain is positive in only 25% of patients.
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