eMedicine Specialties > Emergency Medicine > Toxicology

Plant Poisoning, Oxalates: Treatment & Medication

Author: Jason F Kearney, MD, Consulting Staff, Department of Emergency Medicine, Emergency Medicine Associates, PC, Southwest Washington Medical Center
Coauthor(s): William K Chiang, MD, Associate Professor, Department of Emergency Medicine, New York University School of Medicine; Chief of Service, Department of Emergency Medicine, Bellevue Hospital Center
Contributor Information and Disclosures

Updated: May 27, 2009

Treatment

Prehospital Care

  • Decontaminate mouth, eye, and skin by physically removing all plant material.
  • Treat eye and skin exposure with copious water irrigation.
  • Rescuers should protect themselves from contact with plant materials.

Emergency Department Care

Most exposures are self-limited and only require analgesics for patient comfort.

  • For oral exposures, physically remove any plant material in the oral cavity.
    • Assess for any airway compromise.
    • Individuals without airway compromise can drink cold liquids and eat crushed ice, ice cream, or frozen ice pops or desserts for relief.
    • Oral swishing with diphenhydramine elixir provides local anesthetic and antihistaminic effects.
    • Individuals with laryngeal edema may be treated with antihistamines and observed and/or admitted until edema improves.
    • No clinical data support use of steroids in laryngeal edema induced by oxalate-containing plants.
  • Treat eye exposures with copious water irrigation. Employ slit lamp examination and fluorescein staining to rule out corneal involvement.
  • Skin exposures require irrigation with fluid and local wound care. Some individuals may develop a contact dermatitis.

Consultations

Nearly all cases of houseplant exposures involving oxalate-containing plant species are managed at home in consultation with a regional poison control center. Poison control centers may be helpful with plant identification, particularly if a fax copy or digital picture of the plant can be transmitted.

Medication

Analgesics may be required for pain.

Analgesics

Pain control is essential to quality patient care. Analgesics ensure patient comfort, which is beneficial for patients who have sustained trauma or sustained injuries.


Acetaminophen (Tylenol)

DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, with upper GI disease, or who are taking oral anticoagulants.

Adult

650 mg PO/PR q4h prn

Pediatric

15 mg/kg/dose PO/PR q4h prn

Rifampin can reduce analgesic effects of acetaminophen; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity

Pregnancy

B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals

Precautions

Hepatotoxicity possible in patients with chronic alcoholism following various dose levels; severe or recurrent pain or high or continued fever may indicate serious illness; APAP is contained in many OTC products and combined use with these products may result in cumulative APAP doses exceeding recommended maximum dose (4 g/d)


Ibuprofen (Motrin, Advil)

DOC for patients with mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Adult

200-600 mg PO qid prn

Pediatric

5-10 mg/kg PO q6h prn

Coadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; monitor PT closely (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently

Documented hypersensitivity; peptic ulcer disease, recent GI bleeding or perforation; renal insufficiency; high risk of bleeding

Pregnancy

B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals

D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus

Precautions

Category D in third trimester of pregnancy; caution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in anticoagulation abnormalities or during anticoagulant therapy

Antihistamines

Treatment for significant oral and/or laryngeal edema.


Diphenhydramine (Benadryl)

For symptomatic relief of symptoms caused by release of histamine.

Adult

25-50 mg PO/IV/IM q6h
5 mL of diphenhydramine elixir as oral swish q2h prn

Pediatric

5 mg/kg/d PO/IV/IM divided qid

Potentiates effect of CNS depressants; because of alcohol content, do not give syrup dosage form to patient taking medications that can cause disulfiramlike reactions

Documented hypersensitivity; MAOIs

Pregnancy

B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals

Precautions

May exacerbate angle-closure glaucoma, hyperthyroidism, peptic ulcer, and urinary tract obstruction; first trimester of pregnancy

More on Plant Poisoning, Oxalates

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Treatment & Medication: Plant Poisoning, Oxalates
Follow-up: Plant Poisoning, Oxalates
Multimedia: Plant Poisoning, Oxalates
References

References

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Further Reading

Keywords

plant poisoning, poisonous plant, toxic plants, oxalate crystals, oxalate exposures, Philodendron, Dieffenbachia, Anthurium, Anthurium species, Arum, Araceae, Arisaema species, Caladium, Caladium bicolor, Calla lily, Zantedeschia species, Chinese evergreen, Aglaonema species, Dieffenbachia, Dieffenbachia species, Jack-in-the pulpit, Arisaema triphyllum, Monstera, Ceriman, Monstera deliciosa, Nephthytis, Syngonium podophyllum, Philodendron, Philodendron species, Pothos or Hunter's robe, Epipremnum aureum, skunk cabbage, Symplocarpus foetidus

Contributor Information and Disclosures

Author

Jason F Kearney, MD, Consulting Staff, Department of Emergency Medicine, Emergency Medicine Associates, PC, Southwest Washington Medical Center
Jason F Kearney, MD is a member of the following medical societies: American Academy of Emergency Medicine
Disclosure: Nothing to disclose.

Coauthor(s)

William K Chiang, MD, Associate Professor, Department of Emergency Medicine, New York University School of Medicine; Chief of Service, Department of Emergency Medicine, Bellevue Hospital Center
William K Chiang, MD is a member of the following medical societies: American Academy of Clinical Toxicology, American College of Medical Toxicology, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Medical Editor

Miguel C Fernández, MD, FAAEM, FACEP, FACMT, Associate Clinical Professor; Medical and Managing Director, South Texas Poison Center, Department of Surgery/Emergency Medicine and Toxicology, University of Texas Health Science Center at San Antonio
Miguel C Fernández, MD, FAAEM, FACEP, FACMT is a member of the following medical societies: American Academy of Clinical Toxicology, American Academy of Emergency Medicine, American College of Emergency Physicians, American College of Medical Toxicology, American College of Occupational and Environmental Medicine, Society for Academic Emergency Medicine, and Texas Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

John T VanDeVoort, PharmD, Regional Director of Pharmacy, Sacred Heart & St. Joseph's Hospitals
John T VanDeVoort, PharmD is a member of the following medical societies: American Society of Health-System Pharmacists
Disclosure: Nothing to disclose.

Managing Editor

Michael Hodgman, MD, Assistant Clinical Professor of Medicine, Department of Emergency Medicine, Bassett Healthcare
Michael Hodgman, MD is a member of the following medical societies: American College of Medical Toxicology, American College of Physicians, Medical Society of the State of New York, and Wilderness Medical Society
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Asim Tarabar, MD, Assistant Professor, Department of Surgery, Section of Emergency Medicine, Yale University School of Medicine; Consulting Staff, Department of Emergency Medicine, Yale-New Haven Hospital
Disclosure: Nothing to disclose.

 
 
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