Hypoglycemics Plant Poisoning Differential Diagnoses

  • Author: Jennifer Coles Schecter, MD; Chief Editor: Asim Tarabar, MD   more...
 
Updated: Jan 12, 2011
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Jennifer Coles Schecter, MD  Staff Physician, Department of Emergency Medicine, Lahey Clinic, Burlington, MA

Disclosure: Nothing to disclose.

Coauthor(s)

Sage W Wiener, MD  Assistant Professor, Department of Emergency Medicine, State University of New York Downstate, Director of Medical Toxicology, Department of Emergency Medicine, Kings County Hospital Center

Sage W Wiener, MD is a member of the following medical societies: American Academy of Clinical Toxicology, American Academy of Emergency Medicine, American College of Medical Toxicology, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

B Zane Horowitz, MD, FACMT  Professor, Department of Emergency Medicine, Oregon Health and Sciences University; Medical Director, Oregon Poison Center; Medical Director, Alaska Poison Control System

B Zane Horowitz, MD, FACMT is a member of the following medical societies: American Academy of Clinical Toxicology and American College of Medical Toxicology

Disclosure: Nothing to disclose.

John T VanDeVoort, PharmD  Regional Director of Pharmacy, Sacred Heart & St. Joseph's Hospitals

John T VanDeVoort, PharmD is a member of the following medical societies: American Society of Health-System Pharmacists

Disclosure: Nothing to disclose.

Michael Hodgman, MD  Assistant Clinical Professor of Medicine, Department of Emergency Medicine, Bassett Healthcare

Michael Hodgman, MD is a member of the following medical societies: American College of Medical Toxicology, American College of Physicians, Medical Society of the State of New York, and Wilderness Medical Society

Disclosure: Nothing to disclose.

John D Halamka, MD, MS  Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center

John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Chief Editor

Asim Tarabar, MD  Assistant Professor, Director, Medical Toxicology, Department of Emergency Medicine, Yale University School of Medicine; Consulting Staff, Department of Emergency Medicine, Yale-New Haven Hospital

Disclosure: Nothing to disclose.

References

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  2. US Department of Agriculture. Improve the Detection of Quality Attributes and Chemical Agents in Agricultural Commodities. Last updated November 9, 2009. Available at http://www.ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=215290. Accessed November 10, 2009.

  3. CDC. Toxic hypoglycemic syndrome--Jamaica, 1989-1991. MMWR Morb Mortal Wkly Rep. Jan 31 1992;41(4):53-5. [Medline]. [Full Text].

  4. Meda HA, Diallo B, Buchet JP, Lison D, Barennes H, Ouangre A, et al. Epidemic of fatal encephalopathy in preschool children in Burkina Faso and consumption of unripe ackee (Blighia sapida) fruit. Lancet. Feb 13 1999;353(9152):536-40. [Medline].

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  8. Bressler R. Editorial: The unripe akee - forbidden fruit. N Engl J Med. Aug 26 1976;295(9):500-1. [Medline].

  9. Brun T. Pesticide toxicity or hypoglycine A poisoning (Ivory Coast, 1984)?. Lancet. Apr 23 1988;1(8591):934. [Medline].

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  12. Hernandez-Galicia E, Aguilar-Contreras A, Aguilar-Santamaria L, Roman-Ramos R, Chavez-Miranda AA, Garcia-Vega LM. Studies on hypoglycemic activity of Mexican medicinal plants. Proc West Pharmacol Soc. 2002;45:118-24. [Medline].

  13. Kean EA. Selective inhibition of acyl-CoA dehydrogenases by a metabolite of hypoglycin. Biochim Biophys Acta. Jan 23 1976;422(1):8-14. [Medline].

  14. Khanna P, Jain SC, Panagariya A, Dixit VP. Hypoglycemic activity of polypeptide-p from a plant source. J Nat Prod. Nov-Dec 1981;44(6):648-55. [Medline].

  15. Mentreddy S, Mohamed A, Rimando A. Medicinal Plants with Hypoglycemic/ant-Hyperglycemic Properties: a Review. USDA: Agricultural Research Services. August 2005;Association for the Advancement of Industrial Crops Conference: 20:341-353.

  16. Mills J, Melville GN, Bennett C, West M, Castro A. Effect of hypoglycin A on insulin release. Biochem Pharmacol. Feb 15 1987;36(4):495-7. [Medline].

  17. Mukherjee PK, Maiti K, Mukherjee K, Houghton PJ. Leads from Indian medicinal plants with hypoglycemic potentials. J Ethnopharmacol. Jun 15 2006;106(1):1-28. [Medline].

  18. Nicola WG, Ibrahim KM, Mikhail TH, Girgis RB, Khadr ME. Role of the hypoglycemic plant extract cleome droserifolia in improving glucose and lipid metabolism and its relation to insulin resistance in fatty liver. Boll Chim Farm. Oct 1996;135(9):507-17. [Medline].

  19. Persuad TVN. Foetal abnormalities caused by the active principle of the fruit of Blighia sapida (Akee). West Indian Med J. 1967;16:193-97.

  20. Quere M, Ogouassangni A, Bokossa A, Perra A, Van Damme W. Methylene blue and fatal encephalopathy from ackee fruit poisoning. Lancet. May 8 1999;353(9164):1623. [Medline].

  21. Saxena A, Vikram NK. Role of selected Indian plants in management of type 2 diabetes: a review. J Altern Complement Med. Apr 2004;10(2):369-78. [Medline].

  22. Sherratt HS, Turnbull DM. Methylene blue and fatal encephalopathy from ackee fruit poisoning. Lancet. May 8 1999;353(9164):1623-4. [Medline].

  23. Tanaka K, Kean EA, Johnson B. Jamaican vomiting sickness. Biochemical investigation of two cases. N Engl J Med. Aug 26 1976;295(9):461-7. [Medline].

  24. Barceloux DG. Akee fruit and Jamaican vomiting sickness (Blighia sapida Koenig). Dis Mon. Jun 2009;55(6):318-26. [Medline].

 
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