eMedicine Specialties > Emergency Medicine > Toxicology

Toxicity, Mushroom - Disulfiramlike Toxins: Follow-up

Author: C Crawford Mechem, MD, MS, FACEP, Associate Professor, Department of Emergency Medicine, University of Pennsylvania School of Medicine; Emergency Medical Services Medical Director, Philadelphia Fire Department
Contributor Information and Disclosures

Updated: Jun 1, 2009

Follow-up

Further Inpatient Care

  • Continue supportive care.

Complications

Prognosis

  • The prognosis is excellent.

Patient Education

Miscellaneous

Medicolegal Pitfalls

  • Failure to recognize co-ingestion of other toxic mushrooms, such as Amanita phalloides
  • Failure to recognize an esophageal injury associated with vomiting
  • Failure to recognize ethanol ingestion (eg, cough syrup ingestion)
 


More on Toxicity, Mushroom - Disulfiramlike Toxins

Overview: Toxicity, Mushroom - Disulfiramlike Toxins
Differential Diagnoses & Workup: Toxicity, Mushroom - Disulfiramlike Toxins
Treatment & Medication: Toxicity, Mushroom - Disulfiramlike Toxins
Follow-up: Toxicity, Mushroom - Disulfiramlike Toxins
References

References

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  2. Garbutt JC. The state of pharmacotherapy for the treatment of alcohol dependence. J Subst Abuse Treat. Jan 2009;36(1):S15-23; quiz S24-5. [Medline].

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  4. Tayyareci Y, Acarel E. Acute myocardial infarction associated with disulfiram-alcohol interaction in a young man with normal coronary arteries. Turk Kardiyol Dern Ars. 2009;37(1):48-50. [Medline].

  5. Banys P. The clinical use of disulfiram (Antabuse): a review. J Psychoactive Drugs. Jul-Sep 1988;20(3):243-61. [Medline].

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  8. Carlsson A, Henning M, Lindberg P, Martinson P, Trolin G, Waldeck B, et al. On the disulfiram-like effect of coprine, the pharmacologically active principle of Coprinus atramentarius. Acta Pharmacol Toxicol (Copenh). Apr 1978;42(4):292-7. [Medline].

  9. Christensen JK, Moller IW, Ronsted P, Angelo HR, Johansson B. Dose-effect relationship of disulfiram in human volunteers. I: Clinical studies. Pharmacol Toxicol. Mar 1991;68(3):163-5. [Medline].

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  13. Meyer JH, Herlocher JE, Parisian J. Esophageal rupture after mushroom-alcohol ingestion. N Engl J Med. Dec 2 1971;285(23):1323. [Medline].

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  15. Miller NS, Goodwin DW, Jones FC, Gabrielli WF, Pardo MP, Anand MM, et al. Antihistamine blockade of alcohol-induced flushing in orientals. J Stud Alcohol. Jan 1988;49(1):16-20. [Medline].

  16. Suh JJ, Pettinati HM, Kampman KM, O'Brien CP. The status of disulfiram: a half of a century later. J Clin Psychopharmacol. Jun 2006;26(3):290-302. [Medline].

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Further Reading

Keywords

mushroom toxicity, mushroom poisoning, disulfiram-like toxins, toxic mushrooms, coprine, coprine-containing mushroom toxicity, Coprinus atramentarius, C atramentarius, alcohol inky, inky cap, Clitocybe clavipes, C clavipes, fat-footed clitocybe, clubfoot funnel cap, disulfiram, Antabuse

Contributor Information and Disclosures

Author

C Crawford Mechem, MD, MS, FACEP, Associate Professor, Department of Emergency Medicine, University of Pennsylvania School of Medicine; Emergency Medical Services Medical Director, Philadelphia Fire Department
C Crawford Mechem, MD, MS, FACEP is a member of the following medical societies: American College of Emergency Physicians, National Association of EMS Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Medical Editor

B Zane Horowitz, MD, FACMT, Professor, Fellowship Director, Department of Emergency Medicine, Oregon Health and Sciences University; Medical Director, Oregon Poison Center; Medical Director, Alaska Poison Control System
B Zane Horowitz, MD, FACMT is a member of the following medical societies: American Academy of Clinical Toxicology and American College of Medical Toxicology
Disclosure: Nothing to disclose.

Pharmacy Editor

John T VanDeVoort, PharmD, Regional Director of Pharmacy, Sacred Heart & St. Joseph's Hospitals
John T VanDeVoort, PharmD is a member of the following medical societies: American Society of Health-System Pharmacists
Disclosure: Nothing to disclose.

Managing Editor

Michael Hodgman, MD, Assistant Clinical Professor of Medicine, Department of Emergency Medicine, Bassett Healthcare
Michael Hodgman, MD is a member of the following medical societies: American College of Medical Toxicology, American College of Physicians, Medical Society of the State of New York, and Wilderness Medical Society
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Asim Tarabar, MD, Assistant Professor, Department of Surgery, Section of Emergency Medicine, Yale University School of Medicine; Consulting Staff, Department of Emergency Medicine, Yale-New Haven Hospital
Disclosure: Nothing to disclose.

 
 
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