Toluene Toxicity Differential Diagnoses
- Author: Nathanael J McKeown, DO; Chief Editor: Asim Tarabar, MD more...
Differential Diagnoses
- Alcoholic Ketoacidosis
- Burns, Chemical
- Delirium, Dementia, and Amnesia
- Dermatitis, Contact
- Diabetic Ketoacidosis
- Gastritis and Peptic Ulcer Disease
- Guillain-Barré Syndrome
- Headache, Cluster
- Headache, Tension
- Hepatitis
- Hypocalcemia
- Hypokalemia
- Hypophosphatemia
- Metabolic Acidosis
- Myocardial Infarction
- Pediatrics, Diabetic Ketoacidosis
- Pediatrics, Reactive Airway Disease
- Pediatrics, Sedation
- Pneumonia, Aspiration
- Renal Calculi
- Renal Failure, Acute
- Rhabdomyolysis
- Schizophrenia
- Sinus Bradycardia
- Smoke Inhalation
- Status Epilepticus
- Toxicity, Alcohols
United States Department of Labor. Occupational Safety and Health Administration. Safety and Health topics: Toluene. Last revised March 17, 2004. Available at: http://www.osha.gov/dts/chemicalsampling/data/CH_272200.html.
Broberg K, Tinnerberg H, Axmon A, Warholm M, Rannug A, Littorin M. Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study. Environ Health. Apr 30 2008;7:15. [Medline].
Long, Heather. Inhalants. In: Goldfrank's Toxicologic Emergencies. 8th ed. New York: McGraw-Hill; 2006:1192-1201.
Rosenberg NL, Kleinschmidt-DeMasters BK, Davis KA, Dreisbach JN, Hormes JT, Filley CM. Toluene abuse causes diffuse central nervous system white matter changes. Ann Neurol. Jun 1988;23(6):611-4. [Medline].
Shiomi S, Kuroki T, Kuroda T, et al. Absence of hepatic uptake of Tc-99m phytate in a man with chronic toluene hepatotoxicity. Clin Nucl Med. Aug 1993;18(8):655-6. [Medline].
Atay AA, Kismet E, Turkbay T, Kocaoglu M, Demirkaya E, Sarici SU, et al. Bone mass toxicity associated with inhalation exposure to toluene. Biol Trace Elem Res. Summer 2005;105(1-3):197-203. [Medline].
United States Department of Health and Human Services. Substance Abuse and Mental Health Services Administration, Office of Applied Studies. 2007 National Survey on Drug Use and Health: National Survey. Sept 2008. Available at: http://oas.samhsa.gov/nsduh/2k7nsduh/2k7Results.pdf.
Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, Heard SE. 2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report. Clin Toxicol (Phila). Dec 2008;46(10):927-1057. [Medline].
Flanagan RJ, Ruprah M, Meredith TJ, Ramsey JD. An introduction to the clinical toxicology of volatile substances. Drug Saf. Sep-Oct 1990;5(5):359-83. [Medline].
Medina-Mora ME, Real T. Epidemiology of inhalant use. Curr Opin Psychiatry. May 2008;21(3):247-51. [Medline].
Chao TC, Lo DS, Koh J, et al. Glue sniffing deaths in Singapore--volatile aromatic hydrocarbons in post-mortem blood by headspace gas chromatography. Med Sci Law. Jul 1993;33(3):253-60. [Medline].
Seth R, Kotwal A, Ganguly KK. Street and working children of Delhi, India, misusing toluene: an ethnographic exploration. Subst Use Misuse. 2005;40(11):1659-79. [Medline].
White V, Hayman J. Australian secondary students' use of over-the-counter and illicit substances in 2002. Canberra: Australian Government Department of Health and Ageing; 2004. National Drug Strategy Monograph Series No. 56.
Bowen SE, Daniel J, Balster RL. Deaths associated with inhalant abuse in Virginia from 1987 to 1996. Drug Alcohol Depend. Feb 1 1999;53(3):239-45. [Medline].
Pearson MA, Hoyme HE, Seaver LH, Rimsza ME. Toluene embryopathy: delineation of the phenotype and comparison with fetal alcohol syndrome. Pediatrics. Feb 1994;93(2):211-5. [Medline].
Wick R, Gilbert JD, Felgate P, Byard RW. Inhalant deaths in South Australia: a 20-year retrospective autopsy study. Am J Forensic Med Pathol. Dec 2007;28(4):319-22. [Medline].
Toluene. In: Baselt RC, ed. Disposition of Toxic Drugs and Chemicals in Man. 7th ed. Foster City, CA: Biomedical Publications; 2004:1120-24.
Byrne A, Kirby B, Zibin T, Ensminger S. Psychiatric and neurological effects of chronic solvent abuse. Can J Psychiatry. Dec 1991;36(10):735-8. [Medline].
Caravati EM, Bjerk PJ. Acute toluene ingestion toxicity. Ann Emerg Med. Dec 1997;30(6):838-9. [Medline].
Donald JM, Hooper K, Hopenhayn-Rich C. Reproductive and developmental toxicity of toluene: a review. Environ Health Perspect. Aug 1991;94:237-44. [Medline].
Ellenhorn MJ, Schonwald S, Ordog G. Inhalant abuse. In: Ellenhorn's Medical Toxicology. 2nd ed. Lipincott Williams & Wilkins: 1997:1493-5.
Filley CM, Halliday W, Kleinschmidt-DeMasters BK. The effects of toluene on the central nervous system. J Neuropathol Exp Neurol. Jan 2004;63(1):1-12. [Medline].
Gagnaire F, Langlais C. Relative ototoxicity of 21 aromatic solvents. Arch Toxicol. Jun 2005;79(6):346-54. [Medline].
Gospe SM Jr, Zhou SS. Toluene abuse embryopathy: longitudinal neurodevelopmental effects of prenatal exposure to toluene in rats. Reprod Toxicol. Mar-Apr 1998;12(2):119-26. [Medline].
Maxwell JC. Deaths related to the inhalation of volatile substances in Texas: 1988-1998. Am J Drug Alcohol Abuse. Nov 2001;27(4):689-97. [Medline].
Meulenbelt J, de Groot G, Savelkoul TJ. Two cases of acute toluene intoxication. Br J Ind Med. Jun 1990;47(6):417-20. [Medline].
Shibata K, Yoshita Y, Matsumoto H. Extensive chemical burns from toluene. Am J Emerg Med. May 1994;12(3):353-5. [Medline].
Siqueira LM, Crandall LA. Inhalant use in Florida youth. Subst Abus. Dec 2006;27(4):27-35. [Medline].
Waddell WJ. Toxicologic considerations in the diagnosis of occupational asthma. Ann Allergy Asthma Immunol. Dec 1999;83(6 Pt 2):618-23. [Medline].
Wilkins-Haug L. Teratogen update: toluene. Teratology. Feb 1997;55(2):145-51. [Medline].
Yucel M, Takagi M, Walterfang M, Lubman DI. Toluene misuse and long-term harms: a systematic review of the neuropsychological and neuroimaging literature. Neurosci Biobehav Rev. Jul 2008;32(5):910-26. [Medline].

