Clonidine Toxicity Follow-up
- Author: David Riley, MD, MSc; Chief Editor: Asim Tarabar, MD more...
Further Outpatient Care
Patients with suspected clonidine ingestion may be discharged if they remain asymptomatic for 4-6 hours and have normal vital signs.
Obtain a psychiatric evaluation before discharge for patients with suspected intentional ingestion.
Further Inpatient Care
Admit significantly symptomatic patients with clonidine toxicity to the intensive care unit (ICU).
A ward admission on a monitor is probably reasonable for minimal symptoms if the patient has been observed for several hours with improvement or without worsening. Remember that patients demonstrating clonidine toxicity, secondary to transdermal exposure, may experience a prolonged period of symptoms from a prolonged half-life secondary to a "depot" effect in the subdermal tissues.
Transfer patients with clonidine toxicity if the potential benefits outweigh the risks.
Patients should be taught how to safely discard the clonidine patch and prevent exposure of children.
Prognosis is generally good for patients who present early and have had prompt and proper treatment.
Children may be easily affected by relatively small doses of clonidine. Educating patients about the importance of keeping clonidine and all drugs out of children's reach is critical.
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