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Warfarin and Superwarfarin Toxicity Differential Diagnoses

  • Author: Kent R Olson, MD, FACEP; Chief Editor: Asim Tarabar, MD  more...
Updated: Dec 10, 2015

Diagnostic Considerations

Conditions to consider in the differential diagnosis of warfarin or superwarfarin toxicity include the following:

  • Type A hemophilia
  • Type B hemophilia
  • Munchausen syndrome
  • Munchausen syndrome by proxy
  • Child abuse
  • Epistaxis
  • GI bleeding
  • Ectopic pregnancy
  • Postpartum hemorrhage
  • Hemorrhagic shock
  • Hypovolemic shock
  • Hemorrhagic stroke
  • Subarachnoid hemorrhage
  • Subdural hematoma
  • Vitreous hemorrhage
  • Liver failure
  • Factor X deficiency
  • Factor V deficiency
  • Afibrinogenemia
  • Dysfibrinogenemia
  • Vitamin K deficiency
  • Malabsorptive states
  • Domestic violence
  • Retroperitoneal hemorrhage

Differential Diagnoses

Contributor Information and Disclosures

Kent R Olson, MD, FACEP Clinical Professor of Medicine and Pharmacy, University of California, San Francisco, School of Medicine; Medical Director, San Francisco Division, California Poison Control System

Kent R Olson, MD, FACEP is a member of the following medical societies: American Academy of Clinical Toxicology, American College of Medical Toxicology

Disclosure: Nothing to disclose.


Michael A Miller, MD Assistant Chief, Department of Emergency Medicine, Tripler Army Medical Center; Medical Toxicologist, Tripler Army Medical Center and Central Texas Poison Center, Scott and White Memorial Hospital

Michael A Miller, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, American College of Medical Toxicology

Disclosure: Nothing to disclose.

Lisa M Yungmann Hile, MD Consulting Staff, Medical Director of Emergency Medicine Physician Assistant Fellowship Program, Department of Emergency Medicine, Darnall Army Medical Center

Disclosure: Nothing to disclose.

David N Trickey, MD Staff Physician, Department of Emergency Medicine, Martin Army Community Hospital

David N Trickey, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians

Disclosure: Nothing to disclose.

Derrick Lung, MD, MPH Assistant Clinical Professor, Department of Emergency Medicine, San Francisco General Hospital; Assistant Medical Director, California Poison Control System, San Francisco Division

Derrick Lung, MD, MPH is a member of the following medical societies: American Academy of Clinical Toxicology, American College of Emergency Physicians, American College of Medical Toxicology, Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Chief Editor

Asim Tarabar, MD Assistant Professor, Director, Medical Toxicology, Department of Emergency Medicine, Yale University School of Medicine; Consulting Staff, Department of Emergency Medicine, Yale-New Haven Hospital

Disclosure: Nothing to disclose.


John G Benitez, MD, MPH Associate Professor, Department of Medicine, Medical Toxicology, Vanderbilt University Medical Center; Managing Director, Tennessee Poison Center

John G Benitez, MD, MPH is a member of the following medical societies: American Academy of Clinical Toxicology, American Academy of Emergency Medicine, American College of Medical Toxicology, American College of Preventive Medicine, Society for Academic Emergency Medicine, Undersea and Hyperbaric Medical Society, and Wilderness Medical Society

Disclosure: Nothing to disclose.

David A Peak, MD Assistant Residency Director of Harvard Affiliated Emergency Medicine Residency, Attending Physician, Massachusetts General Hospital; Consulting Staff, Department of Hyperbaric Medicine, Massachusetts Eye and Ear Infirmary

David A Peak, MD is a member of the following medical societies: American College of Emergency Physicians, American Medical Association, Society for Academic Emergency Medicine, and Undersea and Hyperbaric Medical Society

Disclosure: Nothing to disclose.

John T VanDeVoort, PharmD Regional Director of Pharmacy, Sacred Heart and St Joseph's Hospitals

John T VanDeVoort, PharmD is a member of the following medical societies: American Society of Health-System Pharmacists

Disclosure: Nothing to disclose.

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