Close
New

Medscape is available in 5 Language Editions – Choose your Edition here.

 

Hemlock Poisoning Differential Diagnoses

  • Author: Daniel E Brooks, MD; Chief Editor: Asim Tarabar, MD  more...
 
Updated: Apr 21, 2015
 
 

Diagnostic Considerations

Other problems to be considered in the differential diagnosis of hemlock poisoning include the following:

  • Botulism
  • Nicotine (wild tobacco)
  • Golden chain (Laburnum anagyroides)
  • Strychnine
  • Cholinergic poisoning
  • Psychosis
  • Encephalopathy

Differential Diagnoses

 
 
Contributor Information and Disclosures
Author

Daniel E Brooks, MD Co-Medical Director, Banner Good Samaritan Poison and Drug Information Center, Department of Medical Toxicology, Banner Good Samaritan Medical Center

Daniel E Brooks, MD is a member of the following medical societies: American Academy of Clinical Toxicology, American College of Emergency Physicians, American College of Medical Toxicology

Disclosure: Nothing to disclose.

Specialty Editor Board

John T VanDeVoort, PharmD Regional Director of Pharmacy, Sacred Heart and St Joseph's Hospitals

John T VanDeVoort, PharmD is a member of the following medical societies: American Society of Health-System Pharmacists

Disclosure: Nothing to disclose.

Chief Editor

Asim Tarabar, MD Assistant Professor, Director, Medical Toxicology, Department of Emergency Medicine, Yale University School of Medicine; Consulting Staff, Department of Emergency Medicine, Yale-New Haven Hospital

Disclosure: Nothing to disclose.

Additional Contributors

David A Peak, MD Associate Residency Director of Harvard Affiliated Emergency Medicine Residency; Attending Physician, Massachusetts General Hospital; Assistant Professor, Harvard Medical School

David A Peak, MD is a member of the following medical societies: American College of Emergency Physicians, Society for Academic Emergency Medicine, Undersea and Hyperbaric Medical Society, American Medical Association

Disclosure: Partner received salary from Pfizer for employment.

Acknowledgements

Michael Hodgman, MD Assistant Clinical Professor of Medicine, Department of Emergency Medicine, Bassett Healthcare

Michael Hodgman, MD is a member of the following medical societies: American College of Medical Toxicology, American College of Physicians, Medical Society of the State of New York, and Wilderness Medical Society

Disclosure: Nothing to disclose.

References
  1. Mowry JB, Spyker DA, Cantilena LR Jr, McMillan N, Ford M. 2013 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 31st Annual Report. Clin Toxicol (Phila). 2014 Dec. 52(10):1032-283. [Medline]. [Full Text].

  2. Schep LJ, Slaughter RJ, Becket G, Beasley DM. Poisoning due to water hemlock. Clin Toxicol (Phila). 2009 Apr. 47(4):270-8. [Medline].

  3. Uwai K, Ohashi K, Takaya Y. Exploring the structural basis of neurotoxicity in C(17)-polyacetylenes isolated from water hemlock. J Med Chem. 2000 Nov 16. 43(23):4508-15. [Medline].

  4. Furbee B, Wermuth M. Life-threatening plant poisoning. Crit Care Clin. 1997 Oct. 13(4):849-88. [Medline].

  5. Goldfrank LR, Flomenbaum NE, Lewin NA, et al, eds. Goldfrank's Toxicologic Emergencies. 6th ed. Appleton & Lange; 1998. 2, 318, 338, 1246, 1252-3.

  6. Hopkins J. The glycoalkaloids: naturally of interest (but a hot potato?). Food Chem Toxicol. 1995 Apr. 33(4):323-8. [Medline].

  7. Krenzelok EP, Jacobsen TD. Plant exposures ... a national profile of the most common plant genera. Vet Hum Toxicol. 1997 Aug. 39(4):248-9. [Medline].

  8. Lopez TA, Cid MS, Bianchini ML. Biochemistry of hemlock (Conium maculatum L.) alkaloids and their acute and chronic toxicity in livestock. A review. Toxicon. 1999 Jun. 37(6):841-65. [Medline].

  9. Olson KR. Hemlock. Poisoning and Drug Overdose. 3rd ed. Appleton & Lange; 1999. 22, 25, 30, 265-74.

  10. Panter KE, James LF, Gardner DR. Lupines, poison-hemlock and Nicotiana spp: toxicity and teratogenicity in livestock. J Nat Toxins. 1999 Feb. 8(1):117-34. [Medline].

  11. Reynolds T. Hemlock alkaloids from Socrates to poison aloes. Phytochemistry. 2005. 66(12):1399-1406. [Medline].

  12. Vetter J. Poison hemlock (Conium maculatum L.). Food Chem Toxicol. 2004 Sep. 42(9):1373-82. [Medline].

  13. Watson WA, Litovitz TL, Rodgers GC, et al. 2002 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2003 Sep. 21(5):353-421. [Medline].

Previous
Next
 
Hemlock. Photo by Cornell University Poisonous Plants Informational Database
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.