Ankle Dislocation in Emergency Medicine Medication
- Author: James E Keany, MD, FACEP; Chief Editor: Rick Kulkarni, MD more...
Medication Summary
Drugs used to treat the pain associated with dislocations include analgesics and anxiolytics.
Analgesics
Class Summary
Pain control is essential for quality patient care. It ensures patient comfort, promotes pulmonary toilet, and aids physical therapy regimens. Many analgesics have sedating properties that benefit patients who have sustained injuries.
Fentanyl citrate (Duragesic, Sublimaze)
Narcotic analgesic with greater potency and much shorter half-life than morphine sulfate. DOC for conscious sedation analgesia. With short duration (30-60 min) and ease of titration, an excellent choice for pain management and sedation. Easily and quickly reversed by naloxone. After initial dose, subsequent doses should not be titrated more frequently than q3h or q6h.
Oxycodone and acetaminophen (Percocet)
Drug combination indicated for relief of moderately severe to severe pain. DOC for aspirin-hypersensitive patients. Different strengths available.
Oxycodone and aspirin (Percodan)
Drug combination indicated for relief of moderately severe to severe pain.
Codeine/acetaminophen (Tylenol-3)
Drug combination indicated for treatment of mild to moderately severe pain.
Morphine sulfate (MS Contin, MSIR)
DOC for analgesia due to reliable and predictable effects, safety profile, and ease of reversibility with naloxone. Various IV doses are used; commonly titrated until desired effect obtained.
Anxiolytics
Class Summary
Patients with painful injuries usually experience significant anxiety. Anxiolytics allow the clinician to administer a smaller analgesic dose to achieve the same effect.
Diazepam (Valium)
Depresses all levels of CNS, including limbic and reticular formation, possibly by increasing activity of GABA, a major inhibitory neurotransmitter. Individualize dosage and increase cautiously to avoid adverse effects.
Lorazepam (Ativan)
Sedative hypnotic in benzodiazepine class that has short onset of effect and relatively long half-life. By increasing GABA, a major inhibitory neurotransmitter, may depress all levels of CNS, including limbic and reticular formation. When patient needs to be sedated for >1 d this medication is excellent. Monitor patient's blood pressure after administering dose and adjust as necessary.
Thangarajah T, Giotakis N, Matovu E. Bilateral ankle dislocation without malleolar fracture. J Foot Ankle Surg. Sep-Oct 2008;47(5):441-6. [Medline].
Wilson M, Michele A, Jacobsen E. Ankle dislocations without fracture. JBJS. January 1939;21:198-204.
Moehring HD, Tan RT, Marder RA, Lian G. Ankle dislocation. J Orthop Trauma. 1994;8(2):167-72. [Medline].
Tarantino U, Cannata G, Gasbarra E, Bondi L, Celi M, Iundusi R. Open medial dislocation of the ankle without fracture. J Bone Joint Surg Br. Oct 2008;90(10):1382-4. [Medline].
Ross A, Catanzariti AR, Mendicino RW. The hematoma block: a simple, effective technique for closed reduction of ankle fracture dislocations. J Foot Ankle Surg. Jul-Aug 2011;50(4):507-9. [Medline].
Grotz MR, Alpantaki K, Kagda FH, Papacostidis C, Barron D, Giannoudis PV. Open tibiotalar dislocation without associated fracture in a 7-year-old girl. Am J Orthop (Belle Mead NJ). Jun 2008;37(6):E116-8. [Medline].
Lübbeke A, Salvo D, Stern R, Hoffmeyer P, Holzer N, Assal M. Risk factors for post-traumatic osteoarthritis of the ankle: an eighteen year follow-up study. Int Orthop. Jan 17 2012;[Medline].
Agrawal AC, Raza H, Haq R. Closed posterior dislocation of the ankle without fracture. Indian J Orthop. Jul 2008;42(3):360-2. [Medline].
Camarda L, Martorana U, D'Arienzo M. Posterior subtalar dislocation. Orthopedics. Jul 2009;32(7):530. [Medline].
Daffner RH. Ankle trauma. Semin Roentgenol. Apr 1994;29(2):134-51. [Medline].
Daffner RH. Ankle trauma. Radiol Clin North Am. Mar 1990;28(2):395-421. [Medline].
Dean DB. Field management of displaced ankle fractures: techniques for successful reduction. Wilderness Environ Med. Spring 2009;20(1):57-60. [Medline].
Distefano S, Divita G. A case of pure dislocation of the ankle joint. Ital J Orthop Traumatol. Mar 1988;14(1):133-7. [Medline].
Finkemeier C, Engebretsen L, Gannon J. Tibial-talar dislocation without fracture: treatment principles and outcome. Knee Surg Sports Traumatol Arthrosc. 1995;3(1):47-9. [Medline].
Graeme KA, Jackimczyk KC. The extremities and spine. Emerg Med Clin North Am. May 1997;15(2):365-79. [Medline].
Greenbaum MA, Pupp GR. Ankle dislocation without fracture: an unusual case report. J Foot Surg. May-Jun 1992;31(3):238-40. [Medline].
Griffiths HJ. Trauma to the ankle and foot. Crit Rev Diagn Imaging. 1986;26(1):45-105. [Medline].
Krishnamurthy S, Schultz RJ. Pure posteromedial dislocation of the ankle joint. A case report. Clin Orthop Relat Res. Dec 1985;(201):68-70. [Medline].
Merianos P, Papagiannakos K, Hatzis A, Tsafantakis E. Peritalar dislocation: a follow-up report of 21 cases. Injury. Nov 1988;19(6):439-42. [Medline].
Mooney JF, Naylor PT, Poehling GG. Anterolateral ankle dislocation without fracture. South Med J. Feb 1991;84(2):244-7. [Medline].
Schuberth JM. Diagnosis of ankle injuries: the essentials. J Foot Ankle Surg. Mar-Apr 1994;33(2):214. [Medline].
Wehner J, Lorenz M. Lateral ankle dislocation without fracture. J Orthop Trauma. 1990;4(3):362-5. [Medline].
Wilson AB, Toriello EA. Lateral rotatory dislocation of the ankle without fracture. J Orthop Trauma. 1991;5(1):93-5. [Medline].
Wroble RR, Nepola JV, Malvitz TA. Ankle dislocation without fracture. Foot Ankle. Oct 1988;9(2):64-74. [Medline].

