eMedicine Specialties > Emergency Medicine > Trauma & Orthopedics
Fracture, Ankle: Treatment & Medication
Updated: Jul 15, 2008
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
Treatment
Prehospital Care
- Patients with ankle injuries must be evaluated for further trauma.
- For an isolated ankle injury, confirm neurovascular status of the concerned limb, decrease pain, and prevent further damage.
- Cover open fractures with wet sterile gauze.
- Stabilize the suspected fracture site with a pillow splint, air splint, or bulky Jones dressing before transporting patient. Try to immobilize the ankle in a neutral position if possible but avoid excessive handling. Immobilization helps decrease pain, bleeding, and damage to surrounding soft tissue.
- Prehospital reduction of a fracture is not advised unless neurovascular compromise is evident (eg, presence of a cool, dusky foot) and a significantly prolonged transport time is anticipated.
Emergency Department Care
- First, patients should be evaluated for multisystem trauma.
- Once additional trauma is excluded, an ankle fracture should be identified as stable or unstable. Unstable fractures include any fracture-dislocation, any bimalleolar or trimalleolar fracture, or any lateral malleolar fracture with significant talar shift.
- If neurovascular status of the extremity is compromised, the fracture should be reduced as soon as possible and reduction should be maintained during the healing period with a cast, external fixator, or open reduction and internal fixation (ORIF).
- Open fractures should be guarded from further contamination by covering wounds with a wet, sterile dressing secured by loosely wrapped dry sterile gauze.
- Confirm a current tetanus immunization, administering tetanus immunoglobulin when patients lack immunity and harbor a grossly contaminated wound.
- Consider antibiotic prophylaxis, administering cefazolin for mild to moderately contaminated wounds and adding an aminoglycoside for highly contaminated wounds. Administer vancomycin and gentamicin if the patient is allergic to penicillin.
- Leave fracture blisters intact. Once ruptured, blisters are more likely to become contaminated by skin flora.
- Unless neurovascular compromise exists, reduction is best deferred to the orthopedic consultant when an unstable ankle fracture is diagnosed.
- Closed reduction is accomplished as follows (refer to Dislocation, Ankle for specific techniques):
- The orthopedic consultant typically reduces ankle fractures. Ankle dislocations are reduced easily, and physicians treating a new fracture should be skilled in their initial management; however, immediate reduction of a dislocation may not be required unless blood flow to the foot is compromised.
- Provide either local anesthesia with a hematoma block or procedural sedation.
- Closed reduction is best achieved by manipulating the limb to reverse the direction of the original deforming forces. For example, a fracture-dislocation resulting from abductive stress requires pushing the affected site in an adduct direction to restore. Applying a concurrent distracting force often assists reduction attempts.
- Simple, uncomplicated lateral malleolar fractures usually can be splinted in the ED, followed by arrangement of timely orthopedic follow-up care. Bimalleolar, trimalleolar, and pilon fractures necessitate urgent orthopedic attention for possible ORIF.
- Provide analgesics liberally.
- Splinting and casting
- Ankle splints are commercially available or may be constructed by sandwiching 10-12 layers of plaster between 4 sheets of cotton padding.
- Posterior splint: Stable injuries can be treated initially with a posterior splint. Ask the patient to lie prone with the knee bent to a 90-degree angle when applying a posterior splint. Extend the splint from the metatarsal heads along the posterior surface of the leg to the level of the fibular head. Maintain the ankle at a 90-degree angle and mold the splint in the malleolar region.
- Sugar tong/short leg stirrup splint: An alternative to the posterior splint is a sugar tong or short leg stirrup splint. Using 4- or 6-inch plaster, pass the splint under the plantar aspect of the foot, between the calcaneus and metatarsal heads. Secure in place with an elastic wrap.
- Splinting of a fracture with bulky padding (eg, Jones dressing) is indicated when immobilization and compression are needed but swelling is expected to progress. In very unstable ankle fractures, apply a bivalve cast. A normal cast is bivalved by cutting completely through the casting material on the medial and lateral aspects longitudinally to avoid extremity compression. Next, the bivalved cast is overwrapped with an elastic bandage to stabilize the fracture site, while still allowing for swelling and expansion.
Consultations
- Request orthopedic consultation for the following conditions:
- Displaced medial, lateral, or posterior malleolar fracture
- Medial malleolar fracture with lateral ligament damage
- Lateral malleolar fracture with deltoid ligament damage
- Fibula fracture at or proximal to the tibiotalar joint line (eg, Danis-Weber classification type C)
- All bimalleolar fractures
- All trimalleolar fractures
- All intra-articular fractures
- All open fractures
- All pilon fractures
- Consult a vascular surgeon when vascular flow to the ankle or foot is compromised. In a fracture with vascular compromise, angiography may be necessary.
Medication
Provide sufficient analgesia to patients sustaining an ankle fracture. A variety of medications can be used, ranging from oral acetaminophen to parenteral narcotics. For procedural sedation, agents include short-acting sedative-hypnotics and opiate analgesics, usually in combination. In addition, administer tetanus prophylaxis for open fractures.
Narcotic/analgesics
Pain control is essential to quality patient care. Ensures patient comfort, promotes pulmonary toilet, and aids physical therapy regimens. Sedating properties of narcotics benefit patients who have sustained fractures.
Morphine sulfate (Duramorph, Astramorph, MS Contin)
Used to achieve a desired anxiolytic and analgesic effect because easily titrated to desired level of pain control or sedation. Reversed by naloxone.
Adult
2.5-5 mg IV q10-15min prn
Pediatric
Neonates: 0.05-0.2 mg/kg/dose IV prn
Children: 0.1-0.2 mg/kg q2-4h IV prn
Phenothiazines may antagonize analgesic effects; tricyclic antidepressants, MAOIs, and other CNS depressants may potentiate adverse effects
Documented hypersensitivity; hypotension; potentially compromised airway in which establishing rapid airway control would be difficult
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Avoid in hypotension, respiratory depression, nausea, emesis, constipation, and urinary retention; caution in atrial flutter and other supraventricular tachycardias; has vagolytic action and may increase ventricular response rate
Fentanyl citrate (Duragesic, Sublimaze)
Good choice for immediate pain relief and conscious sedation because of its rapid onset and short duration (30-60 min). Easily titrated to desired level of pain control or sedation. Easily reversed by naloxone.
Adult
0.5-2 mcg/kg IV/IM; titrate to desired level of pain control and/or sedation in increments of 25-50 mcg IV
Pediatric
<2 years: 2-3 mcg/kg/dose IV/IM q30-60min
2-12 years: 1-2 mcg/kg IV/IM q60min
>12 years: Administer as in adults
Phenothiazines may antagonize analgesic effects; tricyclic antidepressants may potentiate adverse effects
Documented hypersensitivity; hypotension; potentially compromised airway in which establishing rapid airway control would be difficult
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Caution in hypotension, respiratory depression, constipation, nausea, emesis, and urinary retention; idiosyncratic reaction, known as chest wall rigidity syndrome, may require neuromuscular blockade to increase ventilation
Anxiolytic/hypnotics
Patients with painful injuries usually experience significant anxiety. Anxiolytics allow administration of a smaller analgesic dose to achieve the same effect.
Midazolam hydrochloride (Versed)
Short-acting benzodiazepine/sedative hypnotic used for its anxiolytic, amnestic, and sedating properties. Easily titrated and easily reversed with flumazenil.
Adult
Loading dose: 0.05-0.1 mg/kg IV
Maintenance dose: 0.5-1 mg IV q3min prn; titrate to desired level of sedation
Pediatric
Infants <6 months: Not recommended
6 months to 5 years: 0.05-0.1 mg/kg IV; not to exceed total dose of 0.6 mg/kg
6-12 years: 0.025-0.05 mg/kg IV; not to exceed total dose of 0.4 mg/kg
>12 years: Administer as in adults
Sedative effects may be antagonized by theophyllines; narcotics and erythromycin may accentuate sedative effects due to decreased clearance
Documented hypersensitivity; preexisting hypotension; narrow-angle glaucoma; sensitivity to propylene glycol (diluent)
Pregnancy
D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
Precautions
Caution in congestive heart failure, pulmonary disease, renal impairment, and hepatic failure
Antidotes
In procedural sedation, a benzodiazepine antagonist may be needed to reverse the sedation and respiratory depression resulting from benzodiazepines and narcotics.
An opioid antagonist also can be used to reverse oversedation in a patient manifesting significant respiratory depression.
Flumazenil (Romazicon)
Selective antagonist of benzodiazepine receptor.
Adult
0.2-0.3 mg IV q1min; total dose 2 mg once or 3 mg q1h
Pediatric
Not established
Recommended dose: Initially, 0.01 mg/kg IV over 15 sec, then 0.005-0.01 mg/kg IV q1min intervals; not to exceed 0.2 mg
Caution in cases of mixed drug overdose; toxic effects due to other drugs taken in overdose (eg, cyclic antidepressants) may occur with reversal of benzodiazepine effects
Documented hypersensitivity; serious cyclic-antidepressant overdosage; patients given a benzodiazepine for control of potentially life-threatening condition (eg, increased intracranial pressure or status epilepticus)
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Patients on benzodiazepines for prolonged periods may experience seizures
Naloxone (Narcan)
Prevents or reverses opioid effects including hypotension, respiratory depression, and sedation, possibly by displacing opiates from their receptor. Rapid onset of 1-2 min. Oversedation or respiratory depression should reverse rapidly.
Adult
0.4-2 mg IV
Pediatric
0.01 mg/kg IV
Decreases analgesic effects
Documented hypersensitivity
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Caution in cardiovascular disease; may precipitate withdrawal symptoms in patients addicted to opiates
Antibiotics
Therapy must cover all likely pathogens in the clinical setting.
Cefazolin (Ancef, Kefzol, Zolicef)
Cephalosporin that binds to 1 or more penicillin-binding proteins, arrests bacterial cell wall synthesis, and inhibits bacterial replication. Primarily active against skin flora, including Staphylococcus aureus.
Total daily dosages are the same for IV and IM routes.
Adult
2 g IV/IM q6-12h; not to exceed 12 g/d
Pediatric
25-100 mg/kg/d IV/IM; not to exceed 6 g/d
Probenecid prolongs effect; aminoglycosides may increase renal toxicity; may yield false-positive urine-dip test result for glucose
Documented hypersensitivity
Pregnancy
B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
Precautions
Adjust dose in renal impairment; superinfections and promotion of nonsusceptible organisms may occur with prolonged use or repeated therapy
Gentamicin (Gentacidin, Garamycin)
Aminoglycoside antibiotic used for gram-negative bacterial coverage. Commonly used in combination with both an agent against gram-positive organisms and one that covers anaerobes. Used in conjunction with ampicillin or vancomycin for prophylaxis in patients with open fractures.
Adult
1.5 mg/kg IV; not to exceed 80 mg
Pediatric
2 mg/kg IV
Other aminoglycosides, cephalosporins, penicillins, or amphotericin B may increase nephrotoxicity; enhances effects of neuromuscular blocking agents, thus prolonged respiratory depression may occur; loop diuretics may increase auditory toxicity—possible irreversible hearing loss of varying degrees may occur (monitor regularly)
Documented hypersensitivity; non–dialysis-dependent renal insufficiency
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Narrow therapeutic index (not intended for long-term therapy); caution in renal failure (not on dialysis), myasthenia gravis, hypocalcemia, and conditions that depress neuromuscular transmission; adjust dose in renal impairment
Vancomycin (Vancocin)
Potent antibiotic directed against gram-positive organisms and active against enterococcal species. Also useful in treatment of septicemia and skin structure infections. Used in conjunction with gentamicin for prophylaxis in patients with open fractures.
May need to adjust dose in patients with renal impairment.
Adult
1 g IV over 1 h
Pediatric
Administer as in adults
Erythema, histaminelike flushing, and anaphylactic reactions may occur when administered with anesthetic agents; taken concurrently with aminoglycosides, risk of nephrotoxicity may increase above that with aminoglycoside monotherapy; effects in neuromuscular blockade may be enhanced when coadministered with nondepolarizing muscle relaxants
Documented hypersensitivity
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Caution in renal failure, neutropenia; red man syndrome is caused by too rapid IV infusion (dose given over a few min) but rarely happens when dose given over 2 h or by PO or IP route; red man syndrome not an allergic reaction
Toxoids
These agents are used for tetanus immunization. A booster injection in previously immunized individuals is recommended to prevent this potentially lethal syndrome.
Tetanus toxoid
Used to induce active immunity against tetanus in selected patients; tetanus and diphtheria toxoids are immunizing agents of choice for most adults and children >7 y; administer booster doses throughout life to maintain tetanus immunity; pregnant patients should receive only tetanus toxoid, not a diphtheria antigen-containing product.
In children and adults, may administer into deltoid or midlateral thigh muscles. In infants, preferred site is midthigh laterally.
Adult
Primary immunization: 0.5 mL IM; 2 injections 4-8 wk apart; third dose 6-12 mo after second injection
Booster dose: 0.5 mL IM q10y
Pediatric
Administer as in adults
Patients receiving immunosuppressants, including corticosteroids or radiation therapy, may remain susceptible despite immunization due to poor immune response; cimetidine may enhance or augment delayed-hypersensitivity responses to skin-test antigens; avoid concurrent use of medication with systemic chloramphenicol since it may impair amnestic response to tetanus toxoid; concurrent use of tetanus immune globulin may delay development of active immunity by several days (interaction is nevertheless clinically insignificant and does not preclude its concurrent use)
Documented hypersensitivity; history of any type of neurological symptoms or signs following administration of this product
FDA recommends that elective tetanus immunization be deferred during any outbreak of poliomyelitis because tetanus toxoid injections are an important cause of provocative poliomyelitis
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Do not use to treat actual tetanus infections, or for immediate prophylaxis of unimmunized individuals (use instead tetanus antitoxin, preferably human tetanus immune globulin); diminished antibody response to active immunization may be seen in patients receiving immunosuppressive therapy; better to defer primary diphtheria immunization until immunosuppressive therapy discontinued; routine immunization of symptomatic and asymptomatic HIV-infected persons recommended
Immunoglobulins
Administer tetanus immune globulin to patients who may not have been immunized against Clostridium tetani products.
Tetanus immune globulins (Hyper-Tet)
For passive immunization of persons with wounds that may be contaminated with tetanus spores.
Adult
For prophylaxis: 250-500 U IM in opposite extremity to tetanus toxoid lesion
For clinical tetanus: 3,000-10,000 U IM
Pediatric
For prophylaxis: 250 U IM in opposite extremity to tetanus toxoid
For clinical tetanus: 3,000-10,000 U IM
None reported
Because antibodies in globulin preparation may interfere with immune response to vaccination, do not administer within 3 mo of live-virus immune globulin administration; may be necessary to revaccinate persons who received immune globulin shortly after live-virus vaccination
Pregnancy
C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
Precautions
Persons with isolated IgA deficiency have potential for developing antibodies to IgA and could have anaphylactic reactions to subsequent administration of blood products that contain IgA; do not perform skin testing, since intradermal injection of concentrated gamma globulin may cause localized area of inflammation and can be misinterpreted, causing medication to be withheld from a patient not allergic to this material; true allergic responses to human gamma globulin given in prescribed IM manner are extremely rare; do not admix with other medications since usually incompatible
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| Overview: Fracture, Ankle |
| Differential Diagnoses & Workup: Fracture, Ankle |
Treatment & Medication: Fracture, Ankle |
| Follow-up: Fracture, Ankle |
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Further Reading
Keywords
ankle fracture, broken ankle, ankle joint, ankle injury, Maisonneuve fracture, medial malleolus fractures, open ankle fractures, pilon fracture, pediatric ankle fractures, posterior malleolar fractures, ankle pronation-external (eversion) rotation injuries, ankle supination, adduction injuries, ankle supination external (eversion) rotation injury, ankle syndesmotic injury, ankle trimalleolar fracture, vertical loading of the ankle, pronation dorsiflexion injury, ankle trauma
Treatment & Medication: Fracture, Ankle