eMedicine Specialties > Emergency Medicine > Trauma & Orthopedics

Subdural Hematoma: Differential Diagnoses & Workup

Author: Tom Scaletta, MD, President, Emergency Excellence (EmEx) (www.emergencyexcellence.com); Assistant Professor of Emergency Medicine, Rush Medical College, Cook County Hospital; Chairperson, Department of Emergency Medicine, Edward Hospital; Past-President, American Academy of Emergency Medicine
Contributor Information and Disclosures

Updated: Oct 30, 2009

Differential Diagnoses

Elder Abuse
Stroke, Ischemic
Epidural Hematoma
Subarachnoid Hemorrhage
Meningitis
Pediatrics, Child Abuse
Stroke, Hemorrhagic

Other Problems to Be Considered

Dementia
Brain tumor
Subdural empyema

Workup

Laboratory Studies

  • Complete blood count
  • Coagulation profile
  • Electrolytes
  • Type and screen/cross

Imaging Studies

  • While MRI is superior for demonstrating the size of an acute subdural hematoma (SDH) and its effect on the brain, noncontrast head CT is the primary means of making a diagnosis and suffice for immediate management purposes.
  • Acute SDH typically appears on a noncontrast head CT scan as a hyperdense (white) crescentic mass along the inner table of the skull, most commonly over the cerebral convexity in the parietal region (see Media file 1). The second most common area is above the tentorium cerebelli.


Acute subdural hematoma. Note the bright (white) ...

Acute subdural hematoma. Note the bright (white) image properties of the blood on this noncontrast cranial CT scan. Note also the midline shift. Image courtesy of J. Stephen Huff, MD.

Acute subdural hematoma. Note the bright (white) ...

Acute subdural hematoma. Note the bright (white) image properties of the blood on this noncontrast cranial CT scan. Note also the midline shift. Image courtesy of J. Stephen Huff, MD.

    • Small SDHs may blend in with the adjacent skull and may be appreciated only by adjusting the CT window width to between those generally used to view brain and bone.
    • Some degree of midline shift should be present with moderate or large SDHs. Suspect a contralateral mass when midline shift is absent. If midline shift seems excessive, suspect underlying cerebral edema.
    • SDHs are relatively uncommon in the posterior fossa since the cerebellum undergoes little movement, which is protective of its bridging cortical veins. SDHs that do occur in that location are usually a result of parenchymal cerebellar injury.
    • Interhemispheric SDH causes the falx cerebri to appear thickened and irregular and often is associated with child abuse.1
  • In the subacute phase, the lesion becomes isodense (with respect to the brain) and is more difficult to appreciate on a noncontrast head CT scan (see Media file 2).


Subacute subdural hematoma. The crescent-shaped c...

Subacute subdural hematoma. The crescent-shaped clot is less white than on CT scan of acute subdural hematoma (see Media file 1). In spite of the large clot volume, this patient was awake and ambulatory. Image courtesy of J. Stephen Huff, MD.

Subacute subdural hematoma. The crescent-shaped c...

Subacute subdural hematoma. The crescent-shaped clot is less white than on CT scan of acute subdural hematoma (see Media file 1). In spite of the large clot volume, this patient was awake and ambulatory. Image courtesy of J. Stephen Huff, MD.

    • For this reason, either contrast-enhanced CT or MRI is widely recommended for imaging 48-72 hours after head injury.
    • On T1-weighted MR images, subacute lesions are hyperdense.
    • On contrast-enhanced CT scans, cortical veins over the cerebral surface are opacified and help delineate the lesion.
    • Subacute SDHs often become lens-shaped and can be confused with an epidural hematoma.
  • In the chronic phase, the lesion becomes hypodense and is easy to appreciate on a noncontrast head CT scan.
  • A worsening of the GCS by 2 or more points should prompt repeat imaging in salvageable patients.

More on Subdural Hematoma

Overview: Subdural Hematoma
Differential Diagnoses & Workup: Subdural Hematoma
Treatment & Medication: Subdural Hematoma
Follow-up: Subdural Hematoma
Multimedia: Subdural Hematoma
References
Further Reading

References

  1. Cohen M, Scheimberg I. Subdural haemorrhage and child maltreatment. Lancet. Apr 4 2009;373(9670):1173; author reply 1173-4. [Medline].

  2. Zumofen D, Regli L, Levivier M, Krayenbühl N. Chronic subdural hematomas treated by burr hole trepanation and a subperiostal drainage system. Neurosurgery. Jun 2009;64(6):1116-21; discussion 1121-2. [Medline].

  3. Bullock MR, Chesnut R, Ghajar J, Gordon D, Hartl R, Newell DW. Surgical management of acute subdural hematomas. Neurosurgery. Mar 2006;58(3 Suppl):S16-24; discussion Si-iv. [Medline].

  4. Mobbs R, Khong P. Endoscopic-assisted evacuation of subdural collections. J Clin Neurosci. May 2009;16(5):701-4. [Medline].

  5. Narita E, Maruya J, Nishimaki K, Heianna J, Miyauchi T, Nakahata J, et al. [Case of infected subdural hematoma diagnosed by diffusion-weighted imaging]. Brain Nerve. Mar 2009;61(3):319-23. [Medline].

  6. Bell RS, Neal CJ, Lettieri CJ, Armonda RA. Severe Traumatic Brain Injury: Evolution and Current Surgical Management. Medscape. Available at http://cme.medscape.com/viewarticle/575753. Accessed June 24, 2008.

  7. Buntain BL. Craniocerebral injuries. In: Management of Pediatric Trauma. WB Saunders; 1995:177-88.

  8. Eijkenboom M, Gerlach I, Barker A, et al. Chronic cognitive effects of bilateral subdural haematomas in the rat. Neuroscience. 2004;124(3):523-33. [Medline].

  9. Rockswold GL, Tintinalli JE, ed. Emergency Medicine: A Comprehensive Study Guide. 4th ed. McGraw-Hill; 1996:1142.

  10. Saito T, Kushi H, Makino K, Hayashi N. The risk factors for the occurrence of acute brain swelling in acute subdural hematoma. Acta Neurochir Suppl. 2003;86:351-4. [Medline].

  11. Valadka AB, Narayan RK. Injury to the cranium. In: Trauma. 3rd ed. 1996:267-78.

  12. Wind JJ, Leiphart JW. Images in clinical medicine. Bilateral subacute subdural hematomas. N Engl J Med. Apr 23 2009;360(17):e23. [Medline].

Further Reading

Clinical guidelines

Surgical management of acute subdural hematomas.
Brain Trauma Foundation - Disease Specific Society. 2006 Mar. 9 pages. NGC:005061

ACR Appropriateness Criteria® head trauma.
American College of Radiology - Medical Specialty Society. 1996 (revised 2006). 12 pages. [NGC Update Pending] NGC:005118

Clinical trials

Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI

Internet-Based Treatment for Children With Traumatic Brain Injuries & Their Families: Counselor Assisted Problem Solving (CAPS)

Contributor Information and Disclosures

Author

Tom Scaletta, MD, President, Emergency Excellence (EmEx) (www.emergencyexcellence.com); Assistant Professor of Emergency Medicine, Rush Medical College, Cook County Hospital; Chairperson, Department of Emergency Medicine, Edward Hospital; Past-President, American Academy of Emergency Medicine
Tom Scaletta, MD is a member of the following medical societies: American Academy of Emergency Medicine and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Medical Editor

Richard S Krause, MD, Senior Faculty, Department of Emergency Medicine, State University of New York at Buffalo School of Medicine
Richard S Krause, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

David B Levy, DO, FACEP, FAAEM, Chairman, Department of Emergency Medicine, St Elizabeth Health Center; Associate Professor of Emergency Medicine, Northeastern Ohio Universities College of Medicine
David B Levy, DO, FACEP, FAAEM is a member of the following medical societies: American Academy of Emergency Medicine, American Medical Informatics Association, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Rick Kulkarni, MD, Assistant Professor of Surgery, Section of Emergency Medicine, Yale-New Haven Hospital
Rick Kulkarni, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Emergency Medicine, American College of Emergency Physicians, American Medical Association, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: WebMD Salary Employment

 
 
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