3-Quinuclidinyl Benzilate Poisoning Differential Diagnoses
- Author: Christopher P Holstege, MD; Chief Editor: Robert G Darling, MD, FACEP more...
Differential Diagnoses
- CBRNE - Incapacitating Agents, Agent 15
- CBRNE - Incapacitating Agents, LSD
- Heat Exhaustion and Heatstroke
- Toxicity, Amphetamine
- Toxicity, Anticholinergic
- Toxicity, Antidepressant
- Toxicity, Antihistamine
- Toxicity, Cocaine
- Toxicity, Cyclic Antidepressants
- Toxicity, Hallucinogen
- Toxicity, Lithium
- Toxicity, Methamphetamine
- Toxicity, Phencyclidine
- Toxicity, Salicylate
- Toxicity, Sympathomimetic
Hay A. Surviving the impossible: the long march from Srebrenica. An investigation of the possible use of chemical warfare agents. Med Confl Surviv. Apr-Jun 1998;14(2):120-55. [Medline].
US Army Center for Health Promotion and Preventive Medicine. Psychodelic Agent 3 - Quinuclidinyl Benzilate (BZ). The Deputy for Technical Services' Publication: Detailed Chemical Facts Sheets. 1998;[Full Text].
Byrd GD, Paule RC, Sander LC, et al. Determination of 3-quinuclidinyl benzilate (QNB) and its major metabolites in urine by isotope dilution gas chromatography/mass spectrometry. J Anal Toxicol. May-Jun 1992;16(3):182-7. [Medline].
Gibson RE, Rzeszotarski WJ, Jagoda EM, et al. [125I] 3-quinuclidinyl 4-iodobenzilate: a high affinity, high specific activity radioligand for the M1 and M2-acetylcholine receptors. Life Sci. Jun 4 1984;34(23):2287-96. [Medline].
Glendenning KK. Distribution of muscimol, QNB, and 5HT binding in the vertebrate diencephalon: a comparative study of eight mammals and three non-mammals. Microsc Res Tech. Oct 15 2003;62(3):247-61. [Medline].
Hiramatsu Y, Eckelman WC, Baum BJ. Interaction of iodinated quinuclidinyl benzilate enantiomers with M3 muscarinic receptors. Life Sci. 1994;54(23):1777-83. [Medline].
Holstege CP, Bechtel LK, Reilly TH, Wispelwey BP, Dobmeier SG. Unusual but potential agents of terrorists. Emerg Med Clin North Am. May 2007;25(2):549-66; abstract xi. [Medline].
Hull LA, Rosenblatt DH, Epstein J. 3-Quinuclidinyl benzilate hydrolysis in dilute aqueous solution. J Pharm Sci. Jul 1979;68(7):856-9. [Medline].
J R Army Med Corps. Chemical casualties. Centrally acting incapacitants. J R Army Med Corps. Dec 2002;148(4):388-91. [Medline].
Ketchum JS, Sidell FR. Incapacitating agents. In: Textbook of Military Medicine. 1997:287-305.
McDonough JH Jr, Shih TM. A study of the N-methyl-D-aspartate antagonistic properties of anticholinergic drugs. Pharmacol Biochem Behav. Jun-Jul 1995;51(2-3):249-53. [Medline].
Sorger D, Kampfer I, Schliebs R. Iodo-QNB cortical binding and brain perfusion: effects of a cholinergic basal forebrain lesion in the rat. Nucl Med Biol. Jan 1999;26(1):9-16. [Medline].

