Close
New

Medscape is available in 5 Language Editions – Choose your Edition here.

 

Agent 15 Poisoning Workup

  • Author: Geoffrey M Fitzgerald, MD; Chief Editor: Duane C Caneva, MD, MSc  more...
 
Updated: Apr 10, 2015
 

Laboratory Studies

See the list below:

  • The paucity of distinct diagnostic signs and the lack of any sort of field detector make the diagnosis of Agent 15 toxicity extremely difficult.
  • Maintain a high index of suspicion in scenarios in which terrorist or enemy chemical attack is possible. Multiple casualties exhibiting delirium indicate this diagnosis.
  • Most standard urine toxicology screens do not detect the presence of Agent 15.
  • Confirmatory testing is available at select reference laboratories.
  • Routine laboratory tests can be helpful in ruling out other causes of delirium. These include a CBC, electrolytes, BUN and/or creatinine, glucose, LFTs, toxicology screen, ABG, ammonia level, thyroid stimulating hormone, and lumbar puncture for cerebral spinal fluid.
 
 
Contributor Information and Disclosures
Author

Geoffrey M Fitzgerald, MD Consulting Staff, Concord Emergency Medical Associates

Disclosure: Nothing to disclose.

Coauthor(s)

David P Sole, DO Associate, Department of Emergency Medicine, Faculty, Emergency Medicine Residency Program, Geisinger Medical Center; Clinical Assistant Professor (Adjunct) of Emergency Medicine, Temple University School of Medicine

David P Sole, DO is a member of the following medical societies: American College of Emergency Physicians

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Chief Editor

Duane C Caneva, MD, MSc Senior Medical Advisor to Customs and Border Protection, Department of Homeland Security (DHS) Office of Health Affairs; Federal Co-Chair, Health, Medical, Responder Safety Subgroup, Interagency Board (IAB)

Disclosure: Nothing to disclose.

Additional Contributors

Suzanne White, MD Medical Director, Regional Poison Control Center at Children's Hospital, Program Director of Medical Toxicology, Associate Professor, Departments of Emergency Medicine and Pediatrics, Wayne State University School of Medicine

Suzanne White, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Clinical Toxicology, American College of Epidemiology, American College of Medical Toxicology, American Medical Association, Michigan State Medical Society

Disclosure: Nothing to disclose.

References
  1. Goldfrank L, Flomenbaum N, Lewin N, et al. Anticholinergic poisoning. J Toxicol Clin Toxicol. 1982 Mar. 19(1):17-25. [Medline].

  2. Bowen TE. Emergency War Surgery. Revisionist Press; 1988. 93-94.

  3. Burns MJ, Linden CH, Graudins A, et al. A comparison of physostigmine and benzodiazepines for the treatment of anticholinergic poisoning. Ann Emerg Med. 2000 Apr. 35(4):374-81. [Medline].

  4. Goldfrank LR, Flomenbaum NE. Goldfrank's Toxicologic Emergencies. Appleton & Lange; 1998.

  5. Ketchum JS, Sidell FR. Incapacitating agents. Textbook of Military Medicine, Warfare, Weaponry and the Casualty: Medical Aspects of Chemical and Biological Warfare. United States Government Printing Office; 1997. 287-306.

  6. Schneir AB, Offerman SR, Ly BT, Davis JM, Baldwin RT, Williams SR, et al. Complications of diagnostic physostigmine administration to emergency department patients. Ann Emerg Med. 2003 Jul. 42(1):14-9. [Medline].

  7. Shannon M. Toxicology reviews: physostigmine. Pediatr Emerg Care. 1998 Jun. 14(3):224-6. [Medline].

  8. Tintinalli JE. Anticholinergic toxicity. Emergency Medicine: A Comprehensive Study Guide. McGraw Hill; 2000. 1182-1185.

Previous
Next
 
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.