eMedicine Specialties > Otolaryngology and Facial Plastic Surgery > External Ear Diseases

Otalgia: Differential Diagnoses & Workup

Author: John C Li, MD, Private Practice in Otology and Neurotology; Medical Director, Balance Center
Coauthor(s): Jared Brunk, PA-C, Physician Assistant Certified, Office of John Li, MD
Contributor Information and Disclosures

Updated: Aug 26, 2008

Differential Diagnoses

Acute Laryngitis
Malignant Tumors of the Tonsil
Adenoidectomy
Middle Ear, Acute Otitis Media, Medical Treatment
Allergic Fungal Sinusitis
Middle Ear, Acute Otitis Media, Surgical Treatment
Allergic Rhinitis
Middle Ear, Eustachian Tube, Inflammation/Infection
Barosinusitis
Middle Ear, Mastoiditis
Bell Palsy
Middle Ear, Otitis Media with Effusion
Chronic Laryngitis, Infectious or Allergic
Neck Cancer, Unknown Primary Site
Complications of Otitis Media
Neck, Cervical Metastases, Detection
Contact Granulomas
Neck, Cervical Metastases, Surgery
Deep Neck Infections
Parapharyngeal Space Tumors
Eustachian Tube Function
Parotitis
External Ear, Benign Tumors
Sinusitis, Acute, Medical Treatment
External Ear, Infections
Sinusitis, Chronic, Medical Treatment
External Ear, Inflammatory Diseases
Sinusitis, Maxillary, Acute, Surgical Treatment
External Ear, Malignant External Otitis
Sinusitis, Maxillary, Chronic, Surgical Treatment
Fractures, Mandibular, Alveolar
Sinusitis, Sphenoid, Acute, Surgical Treatment
Fractures, Maxillary, Zygomatic
Skull Base, Petrous Apex, Infection
Malignant Nasopharyngeal Tumors
Skull Base, Petrous Apex, Tumors
Malignant Tumors of the Base of Tongue
Temporal Bone Fractures
Malignant Tumors of the Floor of the Mouth
Thyroid Cancer
Malignant Tumors of the Nasal Cavity
Tonsillectomy
Malignant Tumors of the Sinuses
Tonsillitis and Peritonsillar Abscess
Malignant Tumors of the Temporal Bone

Workup

Laboratory Studies

  • Frequently, the workup suggests that otalgia may be a problem of dental origin.
  • A complete blood cell count may indicate an occult infection.
  • Thyroid function and erythrocyte sedimentation rate (ESR) studies may reveal thyroiditis and temporal arteritis. Chest radiography to seek bronchogenic pathology may be necessary.
  • The perception of aural fullness may be described as ear pain and is observed in conditions associated with endolymphatic hydrops and eustachian tube dysfunction.
  • Ménière disease can be diagnosed by history, audiometrics, and a battery of laboratory tests.
  • In the absence of obvious fluid within the middle ear, aural fullness secondary to eustachian tube dysfunction may manifest with a practically imperceptible bulging or retraction of the tympanic membrane. If autoinsufflation is not effective in relieving this pressure, consider a diagnostic myringotomy.
  • Despite the full battery of testing, a group of patients always remains for whom an etiology is not evident. If not contraindicated, a brief course of nonsteroidal anti-inflammatory agents (NSAIDs) may be helpful.
  • In the authors' study group, 44% of patients without an obvious cause for their ear pain experienced spontaneous resolution. Those in whom symptoms do not resolve must be seen on a regular basis. Follow-up is essential in these cases because of the possibility of discovering a tumor that was initially too small to detect.

Imaging Studies

  • Dental radiography
  • CT scanning: Obtain CT scans of the head or temporal bone, sinuses, and/or neck when no obvious source of the pain can be found. The scan usually includes a brief survey of the sinuses and intracranial contents. CT scanning can reveal significant information about the temporomandibular joint or can be used to diagnose intratemporal lesions.
  • MRI: If indicated by clinical or audiometric suspicion, an MRI may be necessary to define a cerebellopontine angle or other intracranial tumor.
  • Panorex imagery: Panorex imagery is quite useful in diagnosing temporomandibular joint dysfunction, odontogenic pathology, and styloid abnormalities. The high prevalence of dental-related otalgia in the authors' study group underscores the need for an alliance with a person well trained in temporomandibular joint–related disorders. Referral to a competent dentist or oral surgeon may be indicated.
  • PET scanning: As this emerging modality for identifying malignant tumors becomes more readily available, it may be possible to diagnose cancer earlier. PET images fused with CT or MRI adds tremendously detailed information about the location of head and neck neoplasms.

Other Tests

  • Audiography
  • Vestibulocochlear testing
  • Nasal endoscopy
  • Upper aerodigestive tract endoscopy, laryngoscopy
  • Blood tests
    • CBC count
    • WBC count (to look for infection)
    • Sickle cell anemia
    • Thyroid function studies and antibodies for thyroiditis

Procedures

  • When the history and physical examination findings are inconclusive, use of local anesthesia may help localize the problem.
  • The nasal cavity may be sprayed with topical Pontocaine with a vasoconstrictor. After a few minutes of decongestion, some patients with sinus-related pathology experience a relief of headaches, facial pain, and aural fullness.
  • Cetacaine or a 4% lidocaine gargle to anesthetize the oropharynx and larynx can numb pharyngitis or other problem causing referred otalgia.
  • Injectable 1% Xylocaine can be used to identify neuromuscular trigger points and can be useful in the diagnosis of myalgias and neuralgias.
  • Referred signals from the chorda tympani may be numbed via a transcanal or transtympanic injection approach. A few drops of 4% lidocaine or eutectic mixture of local anesthetics 14 (EMLA 14) in the external auditory meatus may help differentiate between a sensitive ear canal and deep temporal pain. Maintain a high index of suspicion for an occult upper respiratory tract tumor, intracranial tumor, intratemporal disease, sinus-related pathology, autoimmune disease, and eustachian tube dysfunction. Consider laboratory evaluation.

More on Otalgia

Overview: Otalgia
Differential Diagnoses & Workup: Otalgia
Treatment & Medication: Otalgia
Follow-up: Otalgia
Multimedia: Otalgia
References

References

  1. Adour KK. Acute temporomandibular joint pain-dysfunction syndrome: neuro-otologic and electromyographic study. Am J Otolaryngol. May 1981;2(2):114-22. [Medline].

  2. Al-Sheikhli AR. Pain in the ear--with special reference to referred pain. J Laryngol Otol. Dec 1980;94(12):1433-40. [Medline].

  3. Frankel VH. Whiplash injuries to the neck. In: Hirsch C, Zotterman Y, eds. Cervical Pain. New York, NY: Pergamon Press; 1971.

  4. Gibson WS Jr, Cochran W. Otalgia in infants and children--a manifestation of gastroesophageal reflux. Int J Pediatr Otorhinolaryngol. 1994;Jan;28(2-3):213-8.

  5. Goethals PL. Referred otalgia. JFMA. Jun 1972;59(6):26-30. [Medline].

  6. Kreisberg MK, Turner J. Dental causes of referred otalgia. Ear Nose Throat J. Oct 1987;66(10):398-408. [Medline].

  7. Kuttila S, Kuttila M, Le Bell Y. Characteristics of subjects with secondary otalgia. J Orofac Pain. Summer 2004;18(3):226-34.

  8. Malik MK, Sharma JK. Referred otalgia of dental origin. J Indian Dent Assoc. Oct 1975;47(10):413-6. [Medline].

  9. Olsen KD. The many causes of otalgia. Infection, trauma, cancer. Postgrad Med. Nov 1 1986;80(6):50-2, 55-6, 61-3. [Medline].

  10. Sataloff RT, Price DB. Distention of the stylomandibular ligament as a cause of styloid pain syndrome. Ear Nose Throat J. Sep 1984;63(9):412-5. [Medline].

  11. Scarbrough TJ, Day TA, Williams TE. Referred otalgia in head and neck cancer: a unifying schema. Am J Clin Oncol. 2003;Oct;26(5):e157-62.

  12. Shah RK, Blevins NH. Otalgia. Otolaryngol Clin North Am. Dec 2003;36(6):1137-51. [Medline].

  13. Subramaniam S, Majid MD. Eagle's syndrome. Med J Malaysia. Mar 2003;58(1):139-41. [Medline].

  14. Thaller SR, De Silva A. Otalgia with a normal ear. Am Fam Physician. Oct 1987;36(4):129-36. [Medline].

  15. Travell JG, Simons DG. Myofascial pain and dysfunction. In: The Trigger Point Manual. Baltimore, Md: Lippincott Williams & Wilkins; 1983.

  16. Wazen JJ. Referred otalgia. Otolaryngol Clin North Am. Dec 1989;22(6):1205-15. [Medline].

  17. Williamson EH. The interrelationship of internal derangements of the temporomandibular joint, headache, vertigo, and tinnitus: a survey of 25 patients. Facial Orthop Temporomandibular Arthrol. Jan 1986;3(1):13-7. [Medline].

  18. Yules RB. Differential diagnosis of referred otalgia. Eye Ear Nose Throat Mon. May 1967;46(5):587-8. [Medline].

Further Reading

Keywords

otalgia, chronic otalgia, chronic, otalgia definition, ear pain, earache, primary otalgia, referred otalgia, external otitis, otitis media, mastoiditis, auricular infections, tympanic membrane perforation, ear infections

Contributor Information and Disclosures

Author

John C Li, MD, Private Practice in Otology and Neurotology; Medical Director, Balance Center
John C Li, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Medical Association, American Neurotology Society, American Tinnitus Association, Florida Medical Association, and North American Skull Base Society
Disclosure: Nothing to disclose.

Coauthor(s)

Jared Brunk, PA-C, Physician Assistant Certified, Office of John Li, MD
Disclosure: Nothing to disclose.

Medical Editor

Michael E Hoffer, MD, Director, Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center of San Diego
Michael E Hoffer, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery
Disclosure: American biloogical group Royalty Other

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Peter S Roland, MD, Professor, Department of Neurological Surgery, Professor and Chairman, Department of Otolaryngology-Head and Neck Surgery, Director of Clinical Center for Auditory, Vestibular and Facial Nerve Disorders, Chief of Pediatric Otology, University of Texas Southwestern Medical Center; Adjunct Professor of Communicative Disorders, University of Texas School of Human Development
Peter S Roland, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngic Allergy, American Academy of Otolaryngology-Head and Neck Surgery, American Auditory Society, American Laryngological Rhinological and Otological Society, American Neurotology Society, American Otological Society, North American Skull Base Society, and Society of University Otolaryngologists-Head and Neck Surgeons
Disclosure: Alcon labs Honoraria Speaking and teaching; GSK Honoraria Speaking and teaching; Advanced Bionics Honoraria Board membership; Cochlear corp Honoraria Board membership; Med El corp travel grants Consulting

CME Editor

Christopher L Slack, MD, Otolaryngology-Facial Plastic Surgery, Private Practice, Associated Coastal ENT; Medical Director, Treasure Coast Sleep Disorders
Christopher L Slack, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Medical Association
Disclosure: Nothing to disclose.

Chief Editor

Arlen D Meyers, MD, MBA, Professor, Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine
Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Head and Neck Society
Disclosure: Covidien Corp Consulting fee Consulting; US Tobacco Corporation unstricted gift unknown; Axis Three Corporation Ownership interest Consulting; Omni Biosciences Ownership interest Consulting; Sentegra Ownership interest Board membership; Syndicom Ownership interest Consulting; Oxlo  Consulting; Medvoy Ownership interest Management position

 
 
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