Radiation Therapy, General Principles: Multimedia

References

1. Fu KK, Pajak TF, Trotti A. A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys. Aug 1 2000;48(1):7-16. [Medline].

2. Eisbruch A, Ten Haken RK, Kim HM. Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer. Int J Radiat Oncol Biol Phys. Oct 1 1999;45(3):577-87. [Medline].

3. Kies MS, Haraf DJ, Athanasiadis I. Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: improved disease control and survival. J Clin Oncol. 1998;16:2715-2721.

4. Bonner JA, Giralt J, Harari PM. Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck: a phase 3 study of high-dose radiation with or without cetuximab. J Clin Oncol. 2004;22 (14S):489 (abstract # 5507).

5. Ang K Kiang, Garden Adam. Radiotherapy for Head and Neck Cancers: Indications and Techniques. 3rd Ed. Lipponcott Williams & Wilkins; 2006.

6. Brizel DM, Wasserman TH, Henke M. Phase III randomized trial of amifostine as a radioprotector in head and neck cancer. J Clin Oncol. Oct 1 2000;18(19):3339-45. [Medline].

7. Chao K S, Apisarnthanarax S, Ozyigit G. Practical Essentials of Intensity Modulated radiation Therapy 2nd Ed. Lippincott Williams & Wilkins;2005.

8. Cooper JS, Pajak TF, Forastiere AA. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med. 2004;350:1937-1944.

9. DeVita V, Hellman S, Rosenberg S. Cancer: Principles and Practice of Oncology. 7th ed. Philadelphia, Pa: Lippincott;2004.

10. Hall E. Radiobiology for the Radiologist. 2nd ed. Hagerstown, Md: Harper & Row;1978.

11. Kahn F. The Physics of Radiation Therapy. Baltimore, Md: Williams & Wilkins;1984.

12. Million R, Cassisi N. Management of Head and Neck Cancer: A Multidisciplinary Approach. 2nd ed. Philadelphia, Pa: Lippincott;1994.

13. Perez C, Brady L. Principles and Practice of Radiation Oncology. 4th ed. Philadelphia, Pa: Lippincott-Raven;2004.

14. Pignon JP, Bourhis J, Domenge C. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet. Mar 18 2000;355(9208):949-55. [Medline].

15. Purdy J, Emmami B. 3-D Radiation Treatment Planning and Conformal Therapy. Madison, Wis. Medical Physics Publishing;1995.

16. Wang CC. Radiation Therapy for Head and Neck Neoplasms: Indications, Techniques, and Results. 2nd ed. Chicago, Ill:. Year Book Medical Publishers;1990.

Further Reading

Clinical guidelines

Beyer DC, Reed DR, Roach III M, Merrick G, Michalski JM, Moran BJ, Rosenthal SA, Rossi CJ, Carroll PR, Higano CS, Expert Panel on Radiation Oncology-Prostate. ACR Appropriateness Criteria® definitive external beam irradiation in stage T1 and T2 prostate cancer. [online publication]. Reston (VA): American College of Radiology (ACR); 2007. 20 p.

Head and Neck Cancer Disease Site Group. Hodson DI, Haines T, Berry M. Symptomatic treatment of radiation-induced xerostomia in head and neck cancer patients [full report]. Toronto (ON): Cancer Care Ontario (CCO); 2004 Mar [online update]. 11 p. (Practice guideline report; no. 5-5).

Related eMedicine topics

Radiation Necrosis

Radiation Enteritis and Proctitis

Intestinal Radiation Injury

Radiation Ulcers

Radiation Therapy, Management of Neck Metastases

Radiation Therapy in Gynecology

Gamma Knife and Other Stereotactic Radiotherapies for Acoustic Neuroma

Prostate Cancer - External Beam Radiotherapy

Postradiation Sarcoma

Osteoradionecrosis of the Mandible

Keywords

radiation, radiation therapy, radiation oncology, cancer treatment, radiotherapy, xerostomia, dry-eye syndrome, intensity modulated radiation therapy, IMRT, radiation-induced cell death, external beam therapy

Contributor Information and Disclosures

Author

Gary J Schreiber, MD, Medical Director, St Francis Hospital of Evanston and Swedish Covenant Hospital of Chicago; Clinical Instructor, Department of Radiation Oncology, Rush University Medical School
Gary J Schreiber, MD is a member of the following medical societies: American Academy of Clinical Psychiatrists
Disclosure: Nothing to disclose.

Medical Editor

Daniel J Kelley, MD, Consulting Staff, Eastern Shore ENT and Allergy Associates and Peninsula Regional Medical Center
Daniel J Kelley, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Head and Neck Society, American Laryngological Rhinological and Otological Society, and Pennsylvania Medical Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Karen Hall Calhoun, MD, Professor, Department of Otolaryngology-Head and Neck Surgery, The Ohio State University
Karen Hall Calhoun, MD is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngic Allergy, American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Head and Neck Society, American Medical Association, American Rhinologic Society, Association for Research in Otolaryngology, Society of University Otolaryngologists-Head and Neck Surgeons, Southern Medical Association, Texas Medical Association, and Texas Medical Association
Disclosure: Nothing to disclose.

CME Editor

Christopher L Slack, MD, Otolaryngology-Facial Plastic Surgery, Private Practice, Associated Coastal ENT; Medical Director, Treasure Coast Sleep Disorders
Christopher L Slack, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Medical Association
Disclosure: Nothing to disclose.

Chief Editor

Arlen D Meyers, MD, MBA, Professor, Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine
Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Head and Neck Society
Disclosure: Covidien Corp Consulting fee Consulting; US Tobacco Corporation unstricted gift unknown; Axis Three Corporation Ownership interest Consulting; Omni Biosciences Ownership interest Consulting; Sentegra Ownership interest Board membership; Syndicom Ownership interest Consulting; Oxlo  Consulting; Medvoy Ownership interest Management position