Presbycusis Treatment & Management

  • Author: Peter S Roland, MD; Chief Editor: Arlen D Meyers, MD, MBA   more...
 
Updated: Mar 11, 2010
 

Medical Care

Presbycusis is not curable, but the effects of the disease on patients’ lives can be mitigated.

  • Amplification devices: Properly fitted hearing aids may contribute to the rehabilitation of a patient with presbycusis. Older patients with arthritis in their fingers and visual difficulties need extra help in learning to use hearing aids. Patients using hearing aids may still experience difficulties with speech discrimination in noisy situations.
  • Lip reading: Lip reading may help patients with diminished speech discrimination and may help hearing aid users who have difficulty in noisy environments.
  • Assistive listening devices: These range from a simple amplification of the telephone signal to a device on the television that sends a signal across the room to a headset worn by a patient with hearing loss. The patient can amplify the sound without disturbing other people with normal hearing who are in the same room.
  • Cochlear implants: Some patients with presbycusis benefit from cochlear implants. Patients with cochlear changes and relatively intact spiral ganglia and central pathways appear to be the best candidates.

These measures are aimed at rehabilitating patients who already experience presbycusis. However, efforts are underway to develop therapies that treat the potential underlying causes of presbycusis, as well as mechanisms to actually prevent the disease altogether. With new studies showing possible genetic and nutritional causes of presbycusis, researchers are proposing treatments that address these underlying causes. For example, medications that block the production of reactive oxygen metabolites may lead to a treatment of presbycusis at the molecular level. Alternatively, a study by Derin et al showed that treatment with I-carnitine resulted in improvement in the ABR results of rats experiencing age-related hearing loss.[15] Unfortunately, most of these therapies are still in the investigational stages.

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Consultations

Rehabilitation of a patient with presbycusis takes time and patience. Specialists in the fields of otolaryngology, audiology, neurology, and psychology may all be involved.

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Diet

No well-established dietary restrictions are prescribed for patients with presbycusis. However, some researchers have recently suggested that a 30% caloric dietary restriction and the use of antioxidant dietary supplements may reduce the production of reactive oxygen metabolites that can harm the inner ear and lead to age-related hearing loss.

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Activity

No activity restrictions are prescribed for patients with presbycusis. However, patients should be warned that exposure to loud sounds can exacerbate sensorineural hearing loss.

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Contributor Information and Disclosures
Author

Peter S Roland, MD  Professor, Department of Neurological Surgery, Professor and Chairman, Department of Otolaryngology-Head and Neck Surgery, Director of Clinical Center for Auditory, Vestibular and Facial Nerve Disorders, Chief of Pediatric Otology, University of Texas Southwestern Medical Center; Adjunct Professor of Communicative Disorders, University of Texas School of Human Development

Peter S Roland, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngic Allergy, American Academy of Otolaryngology-Head and Neck Surgery, American Auditory Society, American Laryngological Rhinological and Otological Society, American Neurotology Society, American Otological Society, North American Skull Base Society, and Society of University Otolaryngologists-Head and Neck Surgeons

Disclosure: Alcon Labs Honoraria Speaking and teaching; GSK Honoraria Speaking and teaching; Advanced Bionics Honoraria Board membership; Cochlear Corp Honoraria Board membership; Med El Corp travel grants Consulting

Coauthor(s)

Joe Walter Kutz Jr, MD  Assistant Professor, Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center

Joe Walter Kutz Jr, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngology-Head and Neck Surgery, American Neurotology Society, and Texas Medical Association

Disclosure: Nothing to disclose.

Michelle C Marcincuk, MD  Clinical Assistant Professor of Otolaryngology, University of Texas Southwestern Medical Center; Consulting Staff, Department of Surgery, Division of Otolaryngology, Texas Health Care, PLLC

Michelle C Marcincuk, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Medical Association, Texas Medical Association, and Triological Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Jack A Shohet, MD  President, Shohet Ear Associates Medical Group, Inc; Associate Clinical Professor, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, School of Medicine

Jack A Shohet, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Medical Association, American Neurotology Society, American Tinnitus Association, and California Medical Association

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Gerard J Gianoli, MD  Clinical Associate Professor, Department of Otolaryngology-Head and Neck Surgery, Tulane University School of Medicine; Vice President, The Ear and Balance Institute; Chief Executive Officer, Ponchartrain Surgery Center

Gerard J Gianoli, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Neurotology Society, American Otological Society, Society of University Otolaryngologists-Head and Neck Surgeons, and Triological Society

Disclosure: Vesticon, Inc. None Board membership

Christopher L Slack, MD  Private Practice in Otolaryngology and Facial Plastic Surgery, Associated Coastal ENT; Medical Director, Treasure Coast Sleep Disorders

Christopher L Slack, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Medical Association

Disclosure: Nothing to disclose.

Chief Editor

Arlen D Meyers, MD, MBA  Professor, Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine

Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Head and Neck Society

Disclosure: Covidien Corp Consulting fee Consulting; US Tobacco Corporation Unrestricted gift Unknown; Axis Three Corporation Ownership interest Consulting; Omni Biosciences Ownership interest Consulting; Sentegra Ownership interest Board membership; Syndicom Ownership interest Consulting; Oxlo Consulting; Medvoy Ownership interest Management position; Cerescan Imaging Honoraria Consulting; GYRUS ACMI Honoraria Consulting

References
  1. Gacek RR, Schuknecht HF. Pathology of presbycusis. Int Audiol. 1969;8:199.

  2. Suga F, Lindsay JR. Histopathological observations of presbycusis. Ann Otol Rhinol Laryngol. Mar-Apr 1976;85(2 pt.1):169-84. [Medline].

  3. Nelson E, Hinojosa R. Presbycusis: a human temporal bone study of individuals with flat audiometric patterns of hearing loss using a new method to quantify stria vascularis volume. Laryngoscope. Oct 2003;113 (10):1672-1686. [Medline].

  4. Nelson EG, Hinojosa R. Presbycusis: a human temporal bone study of individuals with downward sloping audiometric patterns of hearing loss and review of the literature. Laryngoscope. Sep 2006;116(9 Pt 3 Suppl 112):1-12. [Medline].

  5. Dai P, Yang W, Jiang S, et al. Correlation of cochlear blood supply with mitochondrial DNA common deletion in presbyacusis. Acta Otolaryngol. Mar 2004;124(2):130-6. [Medline].

  6. Pickles JO. Mutation in mitochondrial DNA as a cause of presbyacusis. Audiol Neurootol. Jan-Feb 2004;9(1):23-33. [Medline].

  7. Han W, Han D, Jiang S. [Mitochondrial DNA4977 deletions associated with human presbycusis]. Zhonghua Er Bi Yan Hou Ke Za Zhi. Dec 2000;35(6):416-9. [Medline].

  8. Dai P, Jiang S, Gu R. [Cochlear hypoxia and mtDNA deletion: possible correlated factors to cause presbycusis]. Zhonghua Yi Xue Za Zhi. Dec 2000;80(12):897-900. [Medline].

  9. Berner B, Odum L, Parving A. Age-related hearing impairment and B vitamin status. Acta Otolaryngol. Aug 2000;120(5):633-7. [Medline].

  10. Martin Villares C, San Roman Carbajo J, et al. [Lipid profile and hearing-loss aged-related]. Nutr Hosp. Jan-Feb 2005;20(1):52-7. [Medline].

  11. Olzowy B, Canis M, Hempel JM, et al. Effect of atorvastatin on progression of sensorineural hearing loss and tinnitus in the elderly: results of a prospective, randomized, double-blind clinical trial. Otol Neurotol. Jun 2007;28(4):455-8. [Medline].

  12. Pata YS, Akbas Y, Unal M, t al. The relationship between presbycusis and mastoid pneumatization. Yonsei Med J. Feb 29 2004;45(1):68-72. [Medline].

  13. Scholtz AW, Kammen-Jolly K, Felder E, et al. Selective aspects of human pathology in high-tone hearing loss of the aging inner ear. Hearing Res. Jul 2001;157 (1-2):77-86. [Medline].

  14. Kovacii J, Lajtman Z, Ozegovic I, Knezevic P, Caric T, Vlasic A. Investigation of auditory brainstem function in elderly diabetic patients with presbycusis. Int Tinnitus J. 2009;15(1):79-82. [Medline].

  15. Derin A, Agirdir B, Derin N, et al. The effects of L-carnitine on presbyacusis in the rat model. Clin Otolaryngol Allied Sci. Jun 2004;29(3):238-41. [Medline].

  16. Alam SA, Oshima T, Suzuki M, et al. The expression of apoptosis-related proteins in the aged cochlea of Mongolian gerbils. Laryngoscope. Mar 2001;111(3):528-34. [Medline].

  17. Arnesen AR. Presbyacusis--loss of neurons in the human cochlear nuclei. J Laryngol Otol. Jun 1982;96(6):503-11. [Medline].

  18. Bartolome MV, Lopez LM, Gil-Loyzaga P. Galectine-1 expression in cochleae of C57BL/6 mice during aging. Neuroreport. Oct 8 2001;12(14):3107-10. [Medline].

  19. Bhatt K, Liberman M, Nadol J. Morphometric analysis of age-related changes in the human basilar membrane. Ann Otol Rhinol Laryngol. Dec 2001;110 (12):1147-1153. [Medline].

  20. Christensen K, Frederiksen H, Hoffman HJ. Genetic and environmental influences on self-reported reduced hearing in the old and oldest old. J Am Geriatr Soc. Nov 2001;49 (11):1512-1517. [Medline].

  21. Crowe SJ, Guild ST, Polvogt LM. Observations on the pathology of high tonedeafness. Bull Johns Hopkins Hosp. 1934;54:315.

  22. Eavey RD, Gao YZ, Schuknecht HF, et al. Otologic features of bacterial meningitis of childhood. J Pediatr. Mar 1985;106(3):402-7. [Medline].

  23. Harris RW, Reitz ML. Effects of room reverberation and noise on speech discrimination by the elderly. Audiology. 1985;24(5):319-24. [Medline].

  24. Iwai H, Lee S, Inaba M, et al. Correlation between accelerated presbycusis and decreased immune functions. Exp Gerontol. Mar 2003;38(3):319-25. [Medline].

  25. Katsarkas A, Ayukawa H. Hearing loss due to aging (presbycusis). J Otolaryngol. Aug 1986;15(4):239-44. [Medline].

  26. Keithley EM, Canto C, Zheng QY, et al. Age-related hearing loss and the ahl locus in mice. Hear Res. Feb 2004;188(1-2):21-8. [Medline].

  27. Kirikae I, Sato T, Shitora T. Study of hearing in advanced age. Laryngoscope. 1964;74:205.

  28. Lawrence HP. A longitudinal study of the association between tooth loss and age-related hearing loss. Spec Care Dentist. Jul-Aug 2001;21(4):129-40. [Medline].

  29. Lawrence HP, Garcia RI, Essick GK, et al. A longitudinal study of the association between tooth loss and age-related hearing loss. Spec Care Dentist. Jul-Aug 2001;21 (4):129-140. [Medline].

  30. Le T, Keithley EM. Effects of antioxidants on the aging inner ear. Hear Res. Apr 2007;226(1-2):194-202. [Medline].

  31. Liu J, Kong W, Liu Z. [Mitochondrial DNA large deletions associated with presbycusis]. Lin Chuang Er Bi Yan Hou Ke Za Zhi. Nov 2003;17(11):678-80. [Medline].

  32. Makishima K. Clinicopathological studies in presbycusis. Otologia Fukuoka. 1976;13 (Suppl 3):333-66.

  33. Makishima K. Clinicopathological studies in presbycusis. Otologia Fukuoka. 1976;13 (Suppl 1):183.

  34. Nadol JB Jr. Electron microscopic findings in presbycusic degeneration of the basal turn of the human cochlea. Otolaryngol Head Neck Surg. Nov-Dec 1979;87(6):818-36. [Medline].

  35. Nemoto M, Morita Y, Mishima Y, et al. Ahl3, a third locus on mouse chromosome 17 affecting age-related hearing loss. Biochem Biophys Res Commun. Nov 26 2004;324(4):1283-8. [Medline].

  36. Nixon JC, Glorig A, High WS. Changes in air and bone conduction thresholds as a function of age. J Laryngol. 1962;76:288. [Medline].

  37. Picciotti P, Torsello A, Wolf FI, et al. Age-dependent modifications of expression level of VEGF and its receptors in the inner ear. Exp Gerontol. Aug 2004;39(8):1253-8. [Medline].

  38. Roland PS, Marple BF, Meyerhoff WL, eds. Hearing Loss. New York: Thieme Medical Publishers; 1997:206-209.

  39. Saxen A. Inner ear in presbyacusis. Acta Otolaryngol. 1952;41:213.

  40. Saxen A. Pathologie und Klinik der Altersschwerhorigkeit nach Untersuchungen von H. von Fieandt und Arno Saxen. Acta Otolaryngol. 1937;Suppl 23.

  41. Schuknecht HF. Further observations on presbycusis. Arch Otolaryngol. 1964;80:369. [Medline].

  42. Seidman MD. Effects of Dietary Restriction and Antioxidants on Presbycusis. Laryngoscope. May 2000;110(5 Pt 1):727-738. [Medline].

  43. Seidman MD. Effects of dietary restriction and antioxidants on presbycusis. Laryngoscope. May 2000;110 (5 Pt 1):727-738.

  44. Seidman MD, Bai U, Khan MJ, et al. Mitochondrial DNA deletions associated with aging and presbyacusis. Arch Otolaryngol Head Neck Surg. Oct 1997;123(10):1039-45. [Medline].

  45. Welsh LW, Welsh JJ, Healy MP. Central presbycusis. Laryngoscope. Feb 1985;95(2):128-36. [Medline].

  46. Wu H, Du B, Wang P. [Effects of mtDNA deletion associated with abnormal expression in rat cochlear with presbycusis]. Zhonghua Er Bi Yan Hou Ke Za Zhi. Jun 2002;37(3):191-3. [Medline].

  47. Wu T, Marcus DC. Age-related changes in cochlear endolymphatic potassium and potential in CD-1 and CBA/CaJ mice. J Assoc Res Otolaryngol. Sep 2003;4(3):353-62. [Medline].

  48. Zheng QY, Johnson KR. Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice. Hear Res. Apr 2001;154(1-2):45-53. [Medline].

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