Middle Ear, Tympanic Membrane, Infections Medication

  • Author: John Schweinfurth, MD; Chief Editor: Arlen D Meyers, MD, MBA   more...
 
Updated: Mar 12, 2012
 

Medication Summary

Controlled studies of effective antibiotics in various countries demonstrate 80-90% efficacy. See also Otitis Media.

Myringitis is quite painful, and patients frequently request analgesics. Ortophenum, or acetaminophen with codeine (Tylenol #3), is commonly prescribed. See also Otitis Media; External Ear Infections; External Ear, Malignant External Otitis; and External Ear, Inflammatory Diseases.

Good results occur with use of acidifying agents such as acetic acid solution. See External Ear Infections; External Ear, Malignant External Otitis; and External Ear, Inflammatory Diseases.

Next

Analgesics

Class Summary

Pain control is essential to quality patient care. Analgesics ensure patient comfort and have sedating properties, which are beneficial for patients who experience pain.

Diclofenac (Cataflam, Voltaren)

 

Has anti-inflammatory, antipyretic, and analgesic effects. In terms of anti-inflammatory and antipyretic activity, this is much stronger than salicylic acid derivatives, ibuprofen, and butadionum.

Acetaminophen with codeine (Tylenol #3, Ortophenum)

 

Indicated for the treatment of mild-to-moderate pain.

Previous
Next

Keratolytic agents

Class Summary

These agents cause cornified epithelium to swell, soften, macerate, and then desquamate. CAUTION: Any use of ototopical medications should be used with the knowledge of whether a tympanic membrane perforation exists and whether the medication has any ototoxic potential.

Salicylic acid topical

 

May be used as local antiseptic and keratolytic with some benefit. By dissolving the intercellular cement substance, salicylic acid produces desquamation of the horny layer of skin, while not affecting the structure of the viable epidermis.

Previous
Next

Acidifying agents

Class Summary

These agents lower pH levels, which makes the environment unfavorable to microbial growth. CAUTION: Any use of ototopical medications should be used with the knowledge of whether a tympanic membrane perforation exists and whether the medication has any ototoxic potential.

Acetic acid (VoSol)

 

Works well in superficial bacterial infections of otitis externa.

Previous
Proceed to Follow-up
 
 
Contributor Information and Disclosures
Author

John Schweinfurth, MD  Professor, Department of Otolaryngology, University of Mississippi Medical Center

John Schweinfurth, MD is a member of the following medical societies: American Academy of Otolaryngic Allergy, American Academy of Otolaryngology-Head and Neck Surgery, American Laryngological Association, American Medical Association, and Triological Society

Disclosure: Nothing to disclose.

Coauthor(s)

Yuri P Uliyanov, MD, PhD  Director, Department of Ear, Nose, and Throat, Agami Medical Center

Yuri P Uliyanov, MD, PhD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery

Disclosure: Nothing to disclose.

Specialty Editor Board

Michael E Hoffer, MD  Director, Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center of San Diego

Michael E Hoffer, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery

Disclosure: American biloogical group Royalty Other

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Gerard J Gianoli, MD  Clinical Associate Professor, Department of Otolaryngology-Head and Neck Surgery, Tulane University School of Medicine; Vice President, The Ear and Balance Institute; Chief Executive Officer, Ponchartrain Surgery Center

Gerard J Gianoli, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Neurotology Society, American Otological Society, Society of University Otolaryngologists-Head and Neck Surgeons, and Triological Society

Disclosure: Vesticon, Inc. None Board membership

Christopher L Slack, MD  Private Practice in Otolaryngology and Facial Plastic Surgery, Associated Coastal ENT; Medical Director, Treasure Coast Sleep Disorders

Christopher L Slack, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Medical Association

Disclosure: Nothing to disclose.

Chief Editor

Arlen D Meyers, MD, MBA  Professor of Otolaryngology, Dentistry, and Engineering, University of Colorado School of Medicine

Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Head and Neck Society

Disclosure: Covidien Corp Consulting fee Consulting; US Tobacco Corporation Unrestricted gift Unknown; Axis Three Corporation Ownership interest Consulting; Omni Biosciences Ownership interest Consulting; Sentegra Ownership interest Board membership; Medvoy Ownership interest Management position; Cerescan Imaging Consulting; Headwatersmb Consulting fee Consulting; Venturequest Royalty Consulting

References
  1. Crapko M, Kerschner JE, Syring M, Johnston N. Role of extra-esophageal reflux in chronic otitis media with effusion. Laryngoscope. Aug 2007;117(8):1419-23. [Medline].

  2. Rezes S, Késmárki K, Sipka S, Sziklai I. Characterization of otitis media with effusion based on the ratio of albumin and immunoglobulin G concentrations in the effusion. Otol Neurotol. Aug 2007;28(5):663-7. [Medline].

  3. Arnold DJ, Bressler KL. Permeability of tympanotomy tubes to ototopical preparations. Otolaryngol Head Neck Surg. Jul 1999;121(1):35-7. [Medline].

  4. Blevins NH, Karmody CS. Chronic myringitis: prevalence, presentation, and natural history. Otol Neurotol. 2001;Jan;22(1):3-10. [Medline].

  5. Cox L, Macdonald CB. Further Study of the Acoustic Otoscope. Otolaryngology HNS. 1998;119(2):160.

  6. Dawes PJ, Bingham BJ, Rhys R. Aspirating middle ear effusions when inserting ventilation tubes: does it influence post-operative otorrhoea, tube obstruction or the development of tympanosclerosis?. Clin Otolaryngol. Oct 1991;16(5):457-61. [Medline].

  7. Franklin DJ, Starke JR, Brady MT, et al. Chronic otitis media after tympanostomy tube placement caused by Mycobacterium abscessus: a new clinical entity?. Am J Otol. May 1994;15(3):313-20. [Medline].

  8. Hoshino T, Yano J, Ichimura K, Hashimoto H, Nozue M. Chronic myringitis and chronic suppurative otitis media. Arch Otorhinolaryngol. 1982;234(3):219-23. [Medline].

  9. Jaisinghani VJ, Hunter LL, Li Y, Margolis RH. Quantitative analysis of tympanic membrane disease using video-otoscopy. Laryngoscope. 2000;Oct;110(10 Pt 1):1726-30. [Medline].

  10. Jones WS, Kaleida PH. How helpful is pneumatic otoscopy in improving diagnostic accuracy?. Pediatrics. 2003;Sep;112(3 Pt 1):510-3. [Medline].

  11. Jung HH, Cho SD, Yoo CK, Lim HH, Chae SW. Vinegar treatment in the management of granular myringitis. J Laryngol Otol. 2002;Mar;116(3):176-80. [Medline].

  12. Kotikoski MJ, Palmu AA, Nokso-Koivisto J, Kleemola M. Evaluation of the role of respiratory viruses in acute myringitis in children less than two years of age. Pediatr Infect Dis J. 2002;Jul;21(7):636-41. [Medline].

  13. Kotikoski MJ, Palmu AA, Puhakka HJ. The symptoms and clinical course of acute bullous myringitis in children less than two years of age. Int J Pediatr Otorhinolaryngol. 2003;Feb;67(2):165-72. [Medline].

  14. Li Y, Hunter LL, Margolis RH. Prospective study of tympanic membrane retraction, hearing loss, and multifrequency tympanometry. Otolaryngol Head Neck Surg. Nov 1999;121(5):514-22. [Medline].

  15. Ott PM. [The red tympanic membrane] Schweiz Rundsch Med Prax. Review. German. 2004;Oct 13;93(42):1733-7. [Medline].

  16. Palmu AA, Kotikoski MJ, Kaijalainen TH, Puhakka HJ. Bacterial etiology of acute myringitis in children less than two years of age. Pediatr Infect Dis J. 2001;Jun;20(6):607-11. [Medline].

  17. Pichichero ME, Poole MD. Assessing diagnostic accuracy and tympanocentesis skills in the management of otitis media. Arch Pediatr Adolesc Med. 2001;Oct;155(10):1137-42. [Medline].

  18. Ramsay HA, Heikkonen EJ, Laurila PK. Effect of epidermal growth factor on tympanic membranes with chronic perforations: a clinical trial. Otolaryngol Head Neck Surg. Oct 1995;113(4):375-9. [Medline].

  19. Romain O. Pneumatic otoscopy in pediatrics. Arch Pediatr. 2002;Jun;9(6):644-5. French. [Medline].

  20. Schilder AG, Zielhuis GA, Haggard MP. Long-term effects of otitis media with effusion: otomicroscopic findings. Am J Otol. May 1995;16(3):365-72. [Medline].

  21. Uliyanov YP. Method of reception impression of meatus acusticus externus and prints of a membrana tympani. Bulletin of Russian Inventions and Discoveries USSR. 1965;19:Patent: 175173.

  22. van Staaij BK, Rovers MM, Schilder AG, Hoes AW. Accuracy and feasibility of daily infrared tympanic membrane temperature measurements in the identification of fever in children. Int J Pediatr Otorhinolaryngol. 2003;Oct;67(10):1091-7. [Medline].

  23. Weymuller EA Jr. Contemporary antimicrobial therapy. In: Gluckman JL. Renewal of Certification Study Guide in Otolaryngology HNS. 1998:38-45.

  24. Wielgosz R, Fronz Th, Lamprecht J. The Heermann-technique of cartilage palisade tympanoplasty. Long-term results from more than 15,300 operated clinical cases. XYI World Congress of Otorhinolaryngology HNS. 1997;2:1085-8.

  25. Yinglin Z. Three cases of chronic granular myringitis cured by formalin. J Otolaryngol. Dec 1985;14(6):379-80. [Medline].

  26. Casselbrant ML, Mandel EM, Rockette HE, Kurs-Lasky M, Fall PA, Bluestone CD. Adenoidectomy for otitis media with effusion in 2-3-year-old children. Int J Pediatr Otorhinolaryngol. Oct 9 2009;[Medline].

Previous
Next
 
Tympanic membrane (TM) as continuation of the upper wall of external auditory canal (EAC) with angle of incline up to 45 degrees on the border between middle ear and the EAC.
Normal tympanic membrane. Pars tensa (PT), pars flaccida (PF), light reflex (LR), fibrous ring (FR), umbo (Um), handle of malleus (HM), lateral process of malleus (Lpm), anterior plica (AP), posterior plica (PP).
Mirror display of a tympanic membrane surface on the polymeric masc from external acoustical canal of healthy man. Masc of tympanic membrane surface (MtmS).
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.