eMedicine Specialties > Otolaryngology and Facial Plastic Surgery > Nasal & Sinus Diseases
Sinusitis, Sphenoid, Acute, Surgical Treatment: Follow-up
Updated: Jan 2, 2009
Outcome and Prognosis
Outcome and prognosis for sphenoid sinusitis depend highly on early diagnosis. Lew concluded that treatment delay inevitably led to serious morbidity and mortality.2 In his study, 9 out of 15 patients had a delay in treatment. Four patients died, and 4 had irreversible cranial nerve injury. Kibblewhite et al came to similar conclusions.9 In their study of 14 patients with acute sphenoid sinusitis, 57% of the patients had signs of neurologic or ophthalmologic complications, and 29% of the patients were left with permanent disabilities. A delay in diagnosis led to an 80% morbidity rate. The conclusion is that early diagnosis is essential. If properly treated, patients with acute sphenoid sinusitis can improve without complications.
Future and Controversies
Controversies exist in several areas. Administration of broad-spectrum antibiotics is necessary. The choice of antibiotics is not clear. Suggestions in the literature have included gentamicin, chloramphenicol, nafcillin, penicillin, and metronidazole. Direct antibiotic therapy at the likely pathogens, including Staphylococcus aureus and Streptococcus pneumoniae. Consider a drug that crosses the blood-brain barrier if complications are present or seem likely. Adjust antibiotics to cultures when available. Steroid use is generally not indicated.
Acute sphenoid sinusitis can be a devastating disease if not diagnosed quickly. CT scans lead to earlier diagnosis and treatment. Endoscopic approaches to drainage are safe and effective. The combination of these 2 modalities should result in improved outcome and prognosis. In addition, image guidance systems are being used more frequently in sinus surgery. The use of image guidance systems in diseases of the sphenoid is especially helpful and adds an extra dimension of safety to the procedure.
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References
Weisberger EC, Dedo HH. Cranial neuropathies in sinus disease. Laryngoscope. Mar 1977;87(3):357-63. [Medline].
Lew D, Southwick FS, Montgomery WW, et al. Sphenoid sinusitis. A review of 30 cases. N Engl J Med. Nov 10 1983;309(19):1149-54. [Medline].
Hnatuk LA, Macdonald RE, Papsin BC. Isolated sphenoid sinusitis: the Toronto Hospital for Sick Children experience and review of the literature. J Otolaryngol. Feb 1994;23(1):36-41. [Medline].
Lawson W, Reino AJ. Isolated sphenoid sinus disease: an analysis of 132 cases. Laryngoscope. Dec 1997;107(12 Pt 1):1590-5. [Medline].
Sethi DS. Isolated sphenoid lesions: diagnosis and management. Otolaryngol Head Neck Surg. May 1999;120(5):730-6. [Medline].
Welbourn RB. The evolution of transsphenoidal pituitary microsurgery. Surgery. Dec 1986;100(6):1185-90. [Medline].
Metson R, Gliklich RE. Endoscopic treatment of sphenoid sinusitis. Otolaryngol Head Neck Surg. Jun 1996;114(6):736-44. [Medline].
Stankiewicz JA. The endoscopic approach to the sphenoid sinus. Laryngoscope. Feb 1989;99(2):218-21. [Medline].
Kibblewhite DJ, Cleland J, Mintz DR. Acute sphenoid sinusitis: management strategies. J Otolaryngol. Jun 1988;17(4):159-63. [Medline].
Abramovich S, Smelt GJ. Acute sphenoiditis, alone and in concert. J Laryngol Otol. Aug 1982;96(8):751-7. [Medline].
Dale BA, Mackenzie IJ. The complications of sphenoid sinusitis. J Laryngol Otol. Jul 1983;97(7):661-70. [Medline].
Deans JA, Welch AR. Acute isolated sphenoid sinusitis: a disease with complications. J Laryngol Otol. Dec 1991;105(12):1072-4. [Medline].
Grillone GA, Kasnica P. Isolated sphenoid sinus disease. Otolaryngol Clin North Am. 2004;37(2):435-451.
Holt GR, Standefer JA, Brown WE Jr, et al. Infectious diseases of the sphenoid sinus. Laryngoscope. Mar 1984;94(3):330-5. [Medline].
Hsu YC, Su CY, Hsu RF, et al. Abducens palsy in acute isolated sphenoid fungal sinusitis. J Otolaryngol. Oct 2004;33(5):319-21. [Medline].
Postma GN, Chole RA, Nemzek WR. Reversible blindness secondary to acute sphenoid sinusitis. Otolaryngol Head Neck Surg. Jun 1995;112(6):742-6. [Medline].
Tan HK, Ong YK. Acute isolated sphenoid sinusitis. Ann Acad Med Singaore. 2004;33(5):656-659.
Turgut S, Ozcan KM, Celikkanat S, et al. Isolated sphenoid sinusitis. Rhinology. Sep 1997;35(3):132-5. [Medline].
Weiss RL, Bailey BJ. Approaches to the sphenoid. In: Bailey BJ, ed. Head and Neck Surgery - Otolaryngology. 2nd ed. Philadelphia, Pa: Lippincott-Raven; 1998:485-495.
Further Reading
Keywords
sphenoid, sinusitis, acute sphenoiditis, sphenoid sinusitis, acute sinusitis, acute sphenoid sinusitis, sinus infection sphenoid
Follow-up: Sinusitis, Sphenoid, Acute, Surgical Treatment