Nasoorbitoethmoid Fractures Workup
- Author: Travis T Tollefson, MD, MPH, FACS; Chief Editor: Arlen D Meyers, MD, MBA more...
Laboratory Studies
- Beta2-transferrin is the definitive test for CSF rhinorrhea. Collect 1 mL of the suspected fluid in a red top tube. Beta2-transferrin is a "send out" laboratory at most institutions. Watery rhinorrhea that is positive for beta2-transferrin is diagnostic for a CSF leak. Besides CSF, only the vitreous humor of the eye and the perilymph of the ear have been found to contain beta2-transferrin.
- Bloody rhinorrhea suspicious for CSF can be placed on filter paper and observed for a halo sign. If CSF is present, it diffuses faster than blood and results in a clear halo around the central stain.
- Routine chemistry analysis of the rhinorrhea may reveal an elevated glucose content consistent with CSF.
Imaging Studies
Plain radiographs have limited usefulness in aiding the diagnosis of nasoorbitoethmoid (NOE) fractures.
Thin-cut (1.5 mm) axial and coronal (when available) CT scans are the criterion standard for the diagnosis of NOE fractures. Axial CT scan image of comminuted NOE fracture is seen in the image below.
Axial CT scan demonstrates a comminuted nasoorbitoethmoid complex fracture. - Axial images reveal injury to the frontal sinus, lamina papyracea, ethmoid complex, nasal septum, and nasal bones.
- Coronal images detail injuries to the cribriform plate, nasofrontal recess, orbital roof and floor, and lamina papyracea.
- Contrast enhancement of the CSF can assist with the diagnosis of CSF fistula.
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