Medscape is available in 5 Language Editions – Choose your Edition here.


Piriformis Syndrome Treatment & Management

  • Author: Shishir Shah, DO; Chief Editor: Sherwin SW Ho, MD  more...
Updated: Aug 19, 2015

Acute Phase

Rehabilitation Program

Physical Therapy

After a diagnosis of piriformis syndrome has been made, the patient should be instructed to rest from offending activities and initiate physical therapy treatment. Physical therapy modalities are often beneficial forms of treatment when used in conjunction with stretching and manual therapy.

The use of moist heat and/or ultrasound is often recommended before stretching of the piriformis muscle. The piriformis muscle is stretched with flexion, adduction, and internal rotation of the hip adductors and the knee while the patient lies supine. This stretching is performed by bringing the foot of the affected side across and over the knee of the other leg. To enhance the stretch of the piriformis muscle, the physical therapist may perform a muscle-energy technique. This is completed by having the patient abduct the limb against light resistance provided by the therapist for 5-7 seconds, and then it is repeated 5-7 times.

Soft-tissue massage to the gluteal and lumbosacral regions may help to decrease tightness of the affected musculature and reduce irritation of the sciatic nerve. Some physical therapists may be trained in performing myofascial release techniques for the piriformis muscle as well. In addition to stretching the piriformis, the patient should also be instructed to stretch the iliopsoas, tensor fascia latae, hamstrings, and gluteal muscles.

In addition to the specific stretching exercises, the patient can perform the following at home: (1) Before arising from bed, roll side to side and flex and extend the knees while lying on each side. This exercise can be repeated for a total of 5 minutes. (2) Rotate side to side while standing with the arms relaxed for 1 minute every few hours. (3) Take a warm bath with the full body (to the shoulders) immersed; the buoyancy effect is effective. (4) Lie flat on the back and pedal the legs as if riding a bicycle by raising the hips with the hands. (5) Perform knee bends, with as many as 6 repetitions every few hours. A countertop can be used for hand support.

Cold packs and, occasionally, electrical stimulation are applied after exercise or manual therapy. Cold modalities help to decrease pain and inflammation that may have been further triggered by stretching or massage. Remember to stress to patients the importance of light and gradual stretching techniques for the piriformis muscle to avoid overstretching and possible further irritation to the sciatic nerve.

Occupational Therapy

Professions that involve prolonged sitting can worsen symptoms of piriformis syndrome, and patients should avoid sitting for long periods. Patients should be instructed to stand and walk every 20 minutes. Patients should make frequent stops when driving to stand and stretch.

Surgical Intervention

Release of the piriformis tendon and sciatic neurolysis can lead to promising results. Benson and Schutzer performed such a procedure in 14 patients (15 cases) with an average symptom duration of 38 months (minimum, 2 y).[2] All patients had piriformis syndrome secondary to trauma. Benson and Schutzer reported that 11 patients had excellent outcomes, and 4 had good results.[2] Similarly, Frieberg reported favorable results in 10 of 12 patients in whom conservative treatment failed.

Most intraoperative findings include adhesions around the piriformis muscle and anatomic variations of the divisions of the sciatic nerve above, below, and through the belly of the piriformis muscle.


See the list below:

  • Physical therapists are helpful in instructing the patient about the various maneuvers for stretching and pain relief.
  • Referral to an orthopedic surgeon is indicated when the diagnosis is not clear or when conservative therapy fails and a surgical evaluation is needed.
  • Referral to a neurologist and/or neurosurgeon is indicated for EMG studies and for an evaluation of associated disc herniation and spinal stenosis.
  • An osteopathic physician can perform manipulation techniques, along with primary conservative medical intervention. [5]
  • A gynecologist can also assist in differentiating causes of dyspareunia and pelvic pain in women with suspected piriformis syndrome. A gynecologist can assist in identifying trigger points for local injections in female patients via the vaginal route.

Other Treatment

Treatment options to alleviate the pain in the region of the piriformis include the use of local anesthetics, nonsteroidal anti-inflammatory medications (NSAIDs), transrectal massage, ultrasound treatment (~2 W/cm2 for 5-10 min), and manual manipulation. Benson and Schutzer noted a success rate of approximately 85% after conservative treatment with manual therapy and local injections.[2]

  • The most widely recognized treatment is local injection. Local anesthetics (eg, lidocaine, bupivacaine) can be injected in trigger points. The painful piriformis muscle can be identified by palpating the buttocks or by palpating transrectally in males and transvaginally in females. A spinal needle or 25-gauge, 1.5-inch needle is directly aimed at the examining finger. The location is usually through the sciatic notch and inferior to the bony margin; the most common trigger point is 1 inch lateral and caudal to the midpoint of the lateral border of the sacrum. An intramuscular (IM) dose of 50-100 mg can be injected. Studies have established that ultrasound, MRI, and CT-guided piriformis injections can confirm the correct placement of the local anesthetic within the muscle. [6, 7, 8]  A double-blind, randomized study that considered the clinical efficacy of local piriformis muscle injections found that local anesthetic (LA) injections were clinically effective. The authors also reported that the addition of corticosteroid (CS) to LA did not give an additional benefit. [9]
  • Manual manipulation can also be applied (see Physical Therapy above). A common method, mobilization of the spine, is often used by osteopathic physicians (those with a DO degree). [5] The patient is placed in a lateral recumbent position on the unaffected side. The physician faces the patient and rotates the patient’s upper body away by laterally pulling on the lower arm. Then the physician places his or her cephalad hand most superiorly on the paravertebral muscles.The patient’s top leg is brought over the edge of the table. The physician places her caudal hand over the patient's hip in the line of the lowered leg. Force is applied in the direction of the lowered leg but perpendicular to the muscle fibers. When tension is reduced, a thrust (high-velocity low-amplitude [HVLA]) technique can be applied.
  • NSAIDs and opiates can also be administered to patients with piriformis syndrome. However, to the author’s knowledge, no study has been performed to assess the treatment of piriformis pain with intravenous (IV) or oral medications. Physician discretion is recommended in using medications such as those used to treat LBP.

Recovery Phase

Rehabilitation Program

Physical Therapy

In the recovery phase, the patient may begin gradual strengthening activities for the piriformis and gluteal muscles. Therapeutic modalities may be continued through this phase to enhance the benefits of rehabilitation. As the patient becomes asymptomatic, he or she may initiate light sport-specific activities and functional training. Addressing posture and faulty pelvic mechanics is important when resuming activity. Some athletes may need to change their footwear or undergo an orthotic consultation to correct their pelvic alignment and avoid further stress on the piriformis muscle.

Other Treatment (Injection, manipulation, etc.)

See Other Treatment for the acute phase.


Maintenance Phase

Rehabilitation Program

Physical Therapy

During the maintenance phase of rehabilitation, the patient should continue performing a home exercise program for increasing flexibility and strength. Athletes may gradually increase their training volume as tolerated. Runners should be cautious when resuming speed training and hill running, doing so in a gradual fashion with proper warm-up and cool-down periods. Compliance to a daily stretching program is crucial to avoid recurrence of this syndrome. Return to play is dependent on many factors (eg, severity of condition, how soon treatment was initiated, level of patient compliance to program).

Surgical Intervention

See Surgical Intervention for the acute phase.


See Consultations for the acute phase.

Other Treatment

See Other Treatment for the acute phase.

Contributor Information and Disclosures

Shishir Shah, DO Consulting Staff, Comprehensive Woundcare, Banner Baywood Hospital

Shishir Shah, DO is a member of the following medical societies: American Academy of Family Physicians, American Medical Association, American Osteopathic Association

Disclosure: Nothing to disclose.


Thomas W Wang, MD Consulting Staff, Department of Occupational Medicine, Kaiser-Permanente

Thomas W Wang, MD is a member of the following medical societies: American Academy of Family Physicians

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Russell D White, MD Clinical Professor of Medicine, Clinical Professor of Orthopedic Surgery, Department of Community and Family Medicine, University of Missouri-Kansas City School of Medicine, Truman Medical Center-Lakewood

Russell D White, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Family Physicians, American Association of Clinical Endocrinologists, American College of Sports Medicine, American Diabetes Association, American Medical Society for Sports Medicine

Disclosure: Nothing to disclose.

Chief Editor

Sherwin SW Ho, MD Associate Professor, Department of Surgery, Section of Orthopedic Surgery and Rehabilitation Medicine, University of Chicago Division of the Biological Sciences, The Pritzker School of Medicine

Sherwin SW Ho, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, Arthroscopy Association of North America, Herodicus Society, American Orthopaedic Society for Sports Medicine

Disclosure: Received consulting fee from Biomet, Inc. for speaking and teaching; Received grant/research funds from Smith and Nephew for fellowship funding; Received grant/research funds from DJ Ortho for course funding; Received grant/research funds from Athletico Physical Therapy for course, research funding; Received royalty from Biomet, Inc. for consulting.

Additional Contributors

Joseph P Garry, MD, FACSM, FAAFP Associate Professor, Department of Family Medicine and Community Health, University of Minnesota Medical School

Joseph P Garry, MD, FACSM, FAAFP is a member of the following medical societies: American Academy of Family Physicians, American Medical Society for Sports Medicine, Minnesota Medical Association, American College of Sports Medicine

Disclosure: Nothing to disclose.

  1. Jawish RM, Assoum HA, Khamis CF. Anatomical, clinical and electrical observations in piriformis syndrome. J Orthop Surg Res. 2010 Jan 21. 5:3. [Medline]. [Full Text].

  2. Benson ER, Schutzer SF. Posttraumatic piriformis syndrome: diagnosis and results of operative treatment. J Bone Joint Surg Am. 1999 Jul. 81(7):941-9. [Medline].

  3. Beatty RA. The piriformis muscle syndrome: a simple diagnostic maneuver. Neurosurgery. 1994 Mar. 34(3):512-4; discussion 514. [Medline].

  4. Robinson ES, Lindley EM, Gonzalez P, Estes S, Cooley R, Burger EL, et al. Piriformis syndrome versus radiculopathy following lumbar artificial disc replacement. Spine (Phila Pa 1976). 2011 Feb 15. 36(4):E282-7. [Medline].

  5. Boyajian-O'Neill LA, McClain RL, Coleman MK, Thomas PP. Diagnosis and management of piriformis syndrome: an osteopathic approach. J Am Osteopath Assoc. 2008 Nov. 108(11):657-64. [Medline]. [Full Text].

  6. Fowler IM, Tucker AA, Weimerskirch BP, Moran TJ, Mendez RJ. A randomized comparison of the efficacy of 2 techniques for piriformis muscle injection: ultrasound-guided versus nerve stimulator with fluoroscopic guidance. Reg Anesth Pain Med. 2014 Mar-Apr. 39(2):126-32. [Medline].

  7. Blunk JA, Nowotny M, Scharf J, Benrath J. MRI verification of ultrasound-guided infiltrations of local anesthetics into the piriformis muscle. Pain Med. 2013 Oct. 14(10):1593-9. [Medline].

  8. Ozisik PA, Toru M, Denk CC, Taskiran OO, Gundogmus B. CT-guided piriformis muscle injection for the treatment of piriformis syndrome. Turk Neurosurg. 2014. 24(4):471-7. [Medline].

  9. Misirlioglu TO, Akgun K, Palamar D, Erden MG, Erbilir T. Piriformis syndrome: comparison of the effectiveness of local anesthetic and corticosteroid injections: a double-blinded, randomized controlled study. Pain Physician. 2015 Mar-Apr. 18 (2):163-71. [Medline].

  10. Naja Z, Al-Tannir M, El-Rajab M, et al. The effectiveness of clonidine-bupivacaine repeated nerve stimulator-guided injection in piriformis syndrome. Clin J Pain. 2009 Mar-Apr. 25(3):199-205. [Medline].

  11. Filler AG. Piriformis and related entrapment syndromes: diagnosis & management. Neurosurg Clin N Am. 2008 Oct. 19(4):609-22, vii. [Medline].

  12. Greenman PE. Piriformis syndrome. Principles in Manual Medicine. 2nd ed. Baltimore, Md: Lippincott Williams & Wilkins; 1996. 467-74.

  13. Jankiewicz JJ, Hennrikus WL, Houkom JA. The appearance of the piriformis muscle syndrome in computed tomography and magnetic resonance imaging. A case report and review of the literature. Clin Orthop Relat Res. 1991 Jan. 262:205-9. [Medline].

  14. Julsrud ME. Piriformis syndrome. J Am Podiatr Med Assoc. 1989 Mar. 79(3):128-31. [Medline].

  15. Medical Economics. Physicians' Desk Reference. Montvale, NJ: Thompson Medical Economics; 1999.

  16. Merlo IM, Poloni TE, Alfonsi E, Messina AL, Ceroni M. Sciatic pain in a young sportsman. Lancet. 1997 Mar 22. 349(9055):846. [Medline].

  17. Naja Z, Al-Tannir M, El-Rajab M, et al. The effectiveness of clonidine-bupivacaine repeated nerve stimulator-guided injection in piriformis syndrome. Clin J Pain. 2009 Mar-Apr. 25(3):199-205. [Medline].

  18. Ozaki S, Hamabe T, Muro T. Piriformis syndrome resulting from an anomalous relationship between the sciatic nerve and piriformis muscle. Orthopedics. 1999 Aug. 22(8):771-2. [Medline].

  19. Pace JB, Nagle D. Piriformis syndrome. West J Med. 1976. 24:435-9.

  20. Papadopoulos SM, McGillicuddy JE, Albers JW. Unusual cause of 'piriformis muscle syndrome'. Arch Neurol. 1990 Oct. 47(10):1144-6. [Medline].

  21. Parziale JR, Hudgins TH, Fishman LM. The piriformis syndrome. Am J Orthop. 1996 Dec. 25(12):819-23. [Medline].

  22. Pecina HI, Boric I, Smoljanovic T, Duvancic D, Pecina M. Surgical evaluation of magnetic resonance imaging findings in piriformis muscle syndrome. Skeletal Radiol. 2008 Nov. 37(11):1019-23. [Medline].

  23. Silver JK, Leadbetter WB. Piriformis syndrome: assessment of current practice and literature review. Orthopedics. 1998 Oct. 21(10):1133-5. [Medline].

  24. Steiner C, Staubs C, Ganon M, Buhlinger C. Piriformis syndrome: pathogenesis, diagnosis, and treatment. J Am Osteopath Assoc. 1987 Apr. 87(4):318-23. [Medline].

  25. Tibor LM, Sekiya JK. Differential diagnosis of pain around the hip joint. Arthroscopy. 2008 Dec. 24(12):1407-21. [Medline].

Nerve irritation in the herniated disk occurs at the root (sciatic radiculitis). In piriformis syndrome, the irritation extends to the full thickness of the nerve (sciatic neuritis).
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.