eMedicine Specialties > Otolaryngology and Facial Plastic Surgery > Reconstructive Surgery

Mohs Surgery: Multimedia

Author: S Brian Jiang, MD, Associate Clinical Professor of Medicine and Dermatology, Director, Dermatologic and Mohs Micrographic Surgery, University of California School of Medicine, San Diego
Contributor Information and Disclosures

Updated: Aug 7, 2008

Multimedia

Specimen is carefully separated into 4 quadrants.Media file 1: Specimen is carefully separated into 4 quadrants.
Specimen is carefully separated into 4 quadrants.

Specimen is carefully separated into 4 quadrants.

Each quadrant is marked with 2 different color dy...Media file 2: Each quadrant is marked with 2 different color dyes.
Each quadrant is marked with 2 different color dy...

Each quadrant is marked with 2 different color dyes.

Marked tissue is embedded into a chuck for the cr...Media file 3: Marked tissue is embedded into a chuck for the cryostat.
Marked tissue is embedded into a chuck for the cr...

Marked tissue is embedded into a chuck for the cryostat.

Tissue is cut into thin sections.Media file 4: Tissue is cut into thin sections.
Tissue is cut into thin sections.

Tissue is cut into thin sections.

Sections are stained with hematoxylin and eosin a...Media file 5: Sections are stained with hematoxylin and eosin and placed on slides.
Sections are stained with hematoxylin and eosin a...

Sections are stained with hematoxylin and eosin and placed on slides.

Slides are viewed under a microscope.Media file 6: Slides are viewed under a microscope.
Slides are viewed under a microscope.

Slides are viewed under a microscope.

Residual tumors are marked on a map.Media file 7: Residual tumors are marked on a map.
Residual tumors are marked on a map.

Residual tumors are marked on a map.

More on Mohs Surgery

References

References

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  2. Bennett RG. Mohs' surgery: new concepts and applications. In: Bailin PL, Ratz JL, Wheeland RG, eds. Dermatologic Clinics. Philadelphia, Pa: WB Saunders; 1987:409-28.

  3. Bergman R, Azzam H, Sprecher E, et al. A comparative immunohistochemical study of MART-1 expression in Spitz nevi, ordinary melanocytic nevi, and malignant melanomas. J Am Acad Dermatol. Mar 2000;42(3):496-500. [Medline].

  4. Chung VQ, Dwyer PJ, Nehal KS, et al. Use of ex vivo confocal scanning laser microscopy during Mohs surgery for nonmelanoma skin cancers. Dermatol Surg. Dec 2004;30(12 Pt 1):1470-8. [Medline].

  5. Chung VQ, Kelley L, Marra D, et al. Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study. Dermatol Surg. Feb 2006;32(2):193-7. [Medline].

  6. Drake LA, Dinehart SM, Goltz RW, et al. Guidelines of care for Mohs micrographic surgery. American Academy of Dermatology. J Am Acad Dermatol. Aug 1995;33(2 Pt 1):271-8. [Medline].

  7. Finley EM, Katz JL. Mohs micrographic surgery. In: Ratz JL, Geronemus RG, Goldman MP, eds. Textbook of Dermatologic Surgery. Philadelphia, Pa: Lippincott Williams & Wilkins; 1998:417-38.

  8. Friedman PM, Friedman RH, Jiang SB, et al. Microcystic adnexal carcinoma: collaborative series review and update. J Am Acad Dermatol. Aug 1999;41(2 Pt 1):225-31. [Medline].

  9. Harris DW, Kist DA, Bloom K, et al. Rapid staining with carcinoembryonic antigen aids limited excision of extramammary Paget's disease treated by Mohs surgery. J Dermatol Surg Oncol. Apr 1994;20(4):260-4. [Medline].

  10. Jiang SB, Levine VJ, Nehal KS, et al. Er:YAG laser for the treatment of actinic keratoses. Dermatol Surg. May 2000;26(5):437-40. [Medline].

  11. Kirkham N. Tumors and cysts of the epidermis. In: Elder D, Elenitsas R, Jaworsky C, Johnson B, eds. Lever's Histopathology of the Skin. 8th ed. Philadelphia, Pa: Lippincott-Raven; 1997:712-31.

  12. Krunic AL, Garrod DR, Viehman GE, et al. The use of antidesmoglein stains in Mohs micrographic surgery. A potential aid for the differentiation of basal cell carcinoma from horizontal sections of the hair follicle and folliculocentric basaloid proliferation. Dermatol Surg. Jun 1997;23(6):463-8. [Medline].

  13. Lang PG Jr, Osguthorpe JD. Indications and limitations of Mohs micrographic surgery. Dermatol Clin. Oct 1989;7(4):627-44. [Medline].

  14. Miller SJ. The National Comprehensive Cancer Network (NCCN) guidelines of care for nonmelanoma skin cancers. Dermatol Surg. Mar 2000;26(3):289-92. [Medline].

  15. Mohs FE. Frederic E. Mohs, M.D. J Am Acad Dermatol. Nov 1983;9(5):806-14. [Medline].

  16. Mohs FE. Origin and progress of Mohs micrographic surgery. In: Mikhail GR, ed. Mohs Micrographic Surgery. Philadelphia, Pa: WB Saunders; 1991:1-10.

  17. Mohs FE. Mohs micrographic surgery. A historical perspective. Dermatol Clin. Oct 1989;7(4):609-11. [Medline].

  18. Mondragon RM, Barrett TL. Current concepts: the use of immunoperoxidase techniques in mohs micrographic surgery. J Am Acad Dermatol. Jul 2000;43(1 Pt 1):66-71. [Medline].

  19. Ramnarain ND, Walker NP, Markey AC. Basal cell carcinoma: rapid techniques using cytokeratin markers to assist treatment by micrographic (Mohs') surgery. Br J Biomed Sci. Sep 1995;52(3):184-7. [Medline].

  20. Ratner D. Reflections on Mohs micrographic surgery. Skinmed. Jul-Aug 2004;3(4):189-90. [Medline].

  21. Robins P, Albom MJ. Mohs' surgery--fresh tissue technique. J Dermatol Surg. Jun 1975;1(2):37-41. [Medline].

  22. Rowe DE. Comparison of treatment modalities for basal cell carcinoma. Clin Dermatol. Nov-Dec 1995;13(6):617-20. [Medline].

  23. Rowe DE, Carroll RJ, Day CL Jr. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up. J Dermatol Surg Oncol. Mar 1989;15(3):315-28. [Medline].

  24. Rowe DE, Carroll RJ, Day CL Jr. Mohs surgery is the treatment of choice for recurrent (previously treated) basal cell carcinoma. J Dermatol Surg Oncol. Apr 1989;15(4):424-31. [Medline].

  25. Rowe DE, Carroll RJ, Day CL Jr. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J Am Acad Dermatol. Jun 1992;26(6):976-90. [Medline].

  26. Russell BA. Mohs micrographic surgery. In: Freedberg IM, Eisen AZ, Wolff K, eds. Dermatology in General Medicine. 5th ed. New York, NY: McGraw-Hill; 1999:2988-91.

  27. Smeets NW, Kuijpers DI, Nelemans P, et al. Mohs' micrographic surgery for treatment of basal cell carcinoma of the face--results of a retrospective study and review of the literature. Br J Dermatol. Jul 2004;151(1):141-7. [Medline].

  28. Snow SN. Techniques and indications for Mohs micrographic surgery. In: Mikhail GR, ed. Mohs Micrographic Surgery. Philadelphia, Pa: WB Saunders; 1991:. 11-60.

  29. Swanson NA. Mohs surgery. Technique, indications, applications, and the future. Arch Dermatol. Sep 1983;119(9):761-73. [Medline].

  30. Tromovitch TA, Stegman SJ. Microscopic-controlled excision of cutaneous tumors: chemosurgery, fresh tissue technique. Cancer. Feb 1978;41(2):653-8. [Medline].

  31. Zachary CB, Rest EB, Furlong SM, et al. Rapid cytokeratin stains enhance the sensitivity of Mohs micrographic surgery for squamous cell carcinoma. J Dermatol Surg Oncol. Aug 1994;20(8):530-5. [Medline].

Further Reading

Keywords

Mohs surgery, Mohs micrographic surgery, Mohs chemosurgery, Mohs' surgery, Mohs' micrographic surgery, Mohs' chemosurgery, skin cancer, skin cancer surgery, skin lesion, dermatology, fixed-tissue technique, Mohs, basal cell carcinoma, BCC, basal cell cancer, fresh-tissue technique, squamous cell carcinoma, SCC, squamous cell cancer, basal cell nevus syndrome, MOHS, non-melanoma skin cancer, NMSC, dermasurgeon

Contributor Information and Disclosures

Author

S Brian Jiang, MD, Associate Clinical Professor of Medicine and Dermatology, Director, Dermatologic and Mohs Micrographic Surgery, University of California School of Medicine, San Diego
S Brian Jiang, MD is a member of the following medical societies: American Academy of Dermatology, American College of Mohs Micrographic Surgery and Cutaneous Oncology, and American Society for Dermatologic Surgery
Disclosure: Nothing to disclose.

Medical Editor

Clark A Rosen, MD, Director, University of Pittsburgh Voice Center; Associate Professor, Department of Otolaryngology and Communication Science and Disorders, University of Pittsburgh School of Medicine
Clark A Rosen, MD is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Medical Association, and Pennsylvania Medical Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Dominique Dorion, MD, MSc, FRCSC, Program Director and Division Chair, Professor of Surgery, Division of Otolaryngology, University of Sherbrooke, Canada
Disclosure: Nothing to disclose.

CME Editor

Christopher L Slack, MD, Otolaryngology-Facial Plastic Surgery, Private Practice, Associated Coastal ENT; Medical Director, Treasure Coast Sleep Disorders
Christopher L Slack, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Medical Association
Disclosure: Nothing to disclose.

Chief Editor

Arlen D Meyers, MD, MBA, Professor, Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine
Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, and American Head and Neck Society
Disclosure: Covidien Corp Consulting fee Consulting; US Tobacco Corporation unstricted gift unknown

 
 
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