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Complement Deficiency Follow-up

  • Author: Ruchir Agrawal, MD; Chief Editor: Russell W Steele, MD  more...
 
Updated: Feb 18, 2015
 

Deterrence/Prevention

See the list below:

  • Prevention of infections and immediate treatment are important aspects of treatment in patients with complement deficiency. Treat acute infections with appropriate antibiotics and prevent with vaccination.
  • All routine vaccines are recommended. Meningococcal, pneumococcal, and haemophilus vaccinations are recommended for patients and those who are in close contact with them.
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Prognosis

See the list below:

  • Properdin deficiency is associated with a high mortality rate.
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Contributor Information and Disclosures
Author

Ruchir Agrawal, MD Chief, Allergy and Immunology, Aurora Sheboygan Clinic

Ruchir Agrawal, MD is a member of the following medical societies: American Academy of Allergy Asthma and Immunology, American College of Allergy, Asthma and Immunology, American Medical Association, American Academy of Pediatrics

Disclosure: Nothing to disclose.

Coauthor(s)

Harumi Jyonouchi, MD Faculty, Division of Allergy/Immunology and Infectious Diseases, Department of Pediatrics, Saint Peter's University Hospital

Harumi Jyonouchi, MD is a member of the following medical societies: American Academy of Allergy Asthma and Immunology, American Academy of Pediatrics, American Association of Immunologists, American Medical Association, Clinical Immunology Society, New York Academy of Sciences, Society for Experimental Biology and Medicine, Society for Pediatric Research, Society for Mucosal Immunology

Disclosure: Nothing to disclose.

Vishweswar Chilumkurti, MBBS, MPH, MHA Consultant, CEA, Australia

Vishweswar Chilumkurti, MBBS, MPH, MHA is a member of the following medical societies: Medical Council of India, Indian Medical Association, Royal Australian College of General Practitioners

Disclosure: Nothing to disclose.

Specialty Editor Board

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Chief Editor

Russell W Steele, MD Clinical Professor, Tulane University School of Medicine; Staff Physician, Ochsner Clinic Foundation

Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, Southern Medical Association

Disclosure: Nothing to disclose.

Acknowledgements

John Wilson Georgitis, MD Consulting Staff, Lafayette Allergy Services

John Wilson Georgitis, MD is a member of the following medical societies: American Academy of Allergy Asthma and Immunology, American Academy of Pediatrics, American Association for the Advancement of Science, American College of Chest Physicians, American Lung Association, American Medical Writers Association, and American Thoracic Society

Disclosure: Nothing to disclose.

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Scheme showing the cascade of events during the activation of the complement system.
 
 
 
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