Congenital Mitral Stenosis Workup
- Author: M Silvana Horenstein, MD; Chief Editor: Stuart Berger, MD more...
Measure electrolyte balance and renal function if congestive heart failure is suspected.
Electrocardiography findings may be normal in patients with mild MS. Hemodynamically significant stenosis results in ECG findings of left atrial or biatrial enlargement and RV enlargement in proportion to severity of the obstruction.
This may be used to obtain direct intracardiac pressure measurements, the mitral valve gradient, pulmonary vascular resistance, and systemic cardiac output.
The mitral valve effective orifice can be calculated using the Gorlin formula.
The diagnosis and hemodynamic assessment of most patients with MS is performed noninvasively with echocardiography. However, cardiac catheterization is used only when echocardiography does not provide complete information or if the patient undergoes mitral balloon valvuloplasty.
Chest radiographic findings may include may the following:
Left atrial dilation
Posteroanterior (PA) dilation secondary to high pulmonary vascular pressure and resistance
Pulmonary venous congestion
Right ventricular enlargement
Echocardiography is the most important diagnostic tool to evaluate patients with mitral stenosis (MS). This noninvasive imaging modality provides excellent anatomic and hemodynamic assessment of MS.
Echocardiography provides the following:
Direct anatomic data, such as visualization of valve leaflet morphology and motility as well as measurement of valve orifice dimensions
Evaluation of left atrial size and detection of left atrial thrombi
Indirect physiologic data (ie, estimation of pressure gradients across the mitral valve and right ventricular systolic pressure), which may be measured using Doppler echocardiography
Transesophageal echocardiography is used when transthoracic echocardiographic pictures are inadequate. It may also be used to guide intervention and assess results in the operating room and cardiac catheterization laboratory.
Dynamic 3-dimensional transthoracic or transesophageal echocardiography
These techniques can provide good insight into valvular motion and help preoperative planning in situations in which valve reconstruction is considered. However, the accuracy of these techniques is currently limited by the quality of the original 2-dimensional echo cross-sectional images, which can be adversely affected by patient motion, breathing, and cardiac arrhythmia such as atrial fibrillation.
A 2-dimensional echocardiogram of a boy with congenital MS is depicted below.
A 2-dimensional echocardiogram of a patient requiring mitral valve replacement is depicted below.
Magnetic Resonance Imaging
MRI is used infrequently; however, experience with this imaging modality in MS is more limited than with echocardiography.
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