Myocardial Infarction in Childhood Differential Diagnoses
- Author: Louis I Bezold, MD; Chief Editor: Stuart Berger, MD more...
Differential Diagnoses
- Acidosis, Metabolic
- Acidosis, Respiratory
- Acute Lymphoblastic Leukemia
- Acute Respiratory Distress Syndrome
- Afebrile Pneumonia Syndrome
- Anemia, Acute
- Anomalous Left Coronary Artery From the Pulmonary Artery
- Anomalous Left Coronary Artery From the Pulmonary Artery: Surgical Perspective
- Aortic Stenosis, Valvar
- Aortic Valve Insufficiency
- Aortopulmonary Septal Defect
- Ascites
- Aspiration Syndromes
- Atrioventricular Block, Third Degree, Acquired
- Atrioventricular Septal Defect, Complete
- Atrioventricular Septal Defect, Unbalanced
- Bacteremia
- Bundle Branch Block, Left
- Bundle Branch Block, Right
- Cardiomyopathy, Dilated
- Carnitine Deficiency
- Child Abuse & Neglect: Failure to Thrive
- Child Abuse & Neglect: Physical Abuse
- Coarctation of the Aorta
- Coarctation of the Aorta and Interrupted Aortic Arch: Surgical Perspective
- Colic
- Congenital Coronary Abnormalities: Surgical Perspective
- Coronary Artery Anomalies
- Coronary Artery Fistula
- Cyclic Vomiting Syndrome
- Dehydration
- Diabetic Ketoacidosis
- Ebstein Anomaly
- Endocardial Fibroelastosis
- Endocarditis, Bacterial
- Failure to Thrive
- Fever in the Toddler
- Fever in the Young Infant
- Fever Without a Focus
- Heart Failure, Congestive
- Hypoplastic Left Heart Syndrome
- Infantile Polyarteritis Nodosa
- Interrupted Aortic Arch
- Intussusception
- Kawasaki Disease
- Long QT Syndrome
- Lyme Disease
- Marfan Syndrome
- Mitral Stenosis, Acquired
- Mitral Stenosis, Congenital
- Mitral Valve Insufficiency
- Myocarditis, Nonviral
- Myocarditis, Viral
- Pneumococcal Bacteremia
- Pneumonia
- Pulmonary Atresia With Ventricular Septal Defect
- Respiratory Distress Syndrome
- Rheumatic Heart Disease
- Shock
- Shock and Hypotension in the Newborn
- Single Ventricle
- Sinus of Valsalva Aneurysm
- Sudden Infant Death Syndrome
- Supraventricular Tachycardia, Atrial Ectopic Tachycardia
- Supraventricular Tachycardia, Atrioventricular Node Reentry
- Supraventricular Tachycardia, Junctional Ectopic Tachycardia
- Syncope
- Takayasu Arteritis
- Tetralogy of Fallot With Absent Pulmonary Valve
- Tetralogy of Fallot With Pulmonary Atresia
- Tetralogy of Fallot: Surgical Perspective
- Tricuspid Atresia
- Vascular Ring and Sling: Surgical Perspective
- Ventricular Fibrillation
- Ventricular Tachycardia
Concheiro-Guisan A, Sousa-Rouco C, Fernandez-Santamarina I, Gonzalez-Carrero J. Intrauterine myocardial infarction: unsuspected diagnosis in the delivery room. Fetal Pediatr Pathol. Jul-Aug 2006;25(4):179-84. [Medline].
CDC. National Vital Statistics Report: Acute myocardial infarction. 1998 Nov; 47(9). Available at: http://www.disastercenter.com/cdc/aacutcar.html. Accessed September 30, 2008. [Full Text].
Mahle WT, Campbell RM, Favaloro-Sabatier J. Myocardial infarction in adolescents. J Pediatr. Aug 2007;151(2):150-4. [Medline].
Oglesby P. The international cooperative study on epidemiology. Circulation. Jun 1970;41(6):895-7. [Medline].
Lane JR, Ben-Shachar G. Myocardial infarction in healthy adolescents. Pediatrics. Oct 2007;120(4):e938-43. [Medline].
Safi M, Taherkhani M, Badalabadi RM, Eslami V, Movahed MR. Coronary aneurysm and silent myocardial infarction in an adolescent secondary to undiagnosed childhood Kawasaki disease. Exp Clin Cardiol. Spring 2010;15(1):e18-9. [Medline]. [Full Text].
Hunley TE, Kon V, Jabs K. Myocardial infarction in chronic kidney disease. Pediatrics. Jul 2008;122(1):223-4; author reply 224. [Medline].
Ardoin SP, Sandborg C, Schanberg LE. Management of dyslipidemia in children and adolescents with systemic lupus erythematosus. Lupus. 2007;16(8):618-26. [Medline].
Koestenberger M, Nagel B, Gamillscheg A, Temmel W, Cvirn G, Beitzke A. Myocardial infarction in an adolescent: anomalous origin of the left main coronary artery from the right coronary sinus in association with combined prothrombotic defects. Pediatrics. Aug 2007;120(2):e424-7. [Medline].
Fyfe DA, Ketchum D, Lewis R, et al. Tissue Doppler imaging detects severely abnormal myocardial velocities that identify children with pre-terminal cardiac graft failure after heart transplantation. J Heart Lung Transplant. May 2006;25(5):510-7. [Medline].
Tacke CE, Kuipers IM, Groenink M, Spijkerboer AM, Kuijpers TW. Cardiac magnetic resonance imaging for noninvasive assessment of cardiovascular disease during the follow-up of patients with kawasaki disease. Circ Cardiovasc Imaging. Nov 1 2011;4(6):712-20. [Medline].
Whitham JK, Hasan BS, Schamberger MS, Johnson TR. Use of cardiac magnetic resonance imaging to determine myocardial viability in an infant with in utero septal myocardial infarction and ventricular noncompaction. Pediatr Cardiol. Sep 2008;29(5):950-3. [Medline].
Gazit AZ, Avari JN, Balzer DT, Rhee EK. Electrocardiographic diagnosis of myocardial ischemia in children: is a diagnostic electrocardiogram always diagnostic?. Pediatrics. Aug 2007;120(2):440-4. [Medline].
Towbin JA, Bricker JT, Garson A Jr. Electrocardiographic criteria for diagnosis of acute myocardial infarction in childhood. Am J Cardiol. Jun 15 1992;69(19):1545-8. [Medline].
Lim CW, Ho KT, Quek SC. Exercise myocardial perfusion stress testing in children with Kawasaki disease. J Paediatr Child Health. Jul-Aug 2006;42(7-8):419-22. [Medline].
Sugahara Y, Ishii M, Muta H, Iemura M, Matsuishi T, Kato H. Warfarin therapy for giant aneurysm prevents myocardial infarction in Kawasaki disease. Pediatr Cardiol. Mar 2008;29(2):398-401. [Medline].
Ahn YK, Jeong MH, Bom HS, et al. Myocardial infarction with Moyamoya disease and pituitary gigantism in a young female patient. Jpn Circ J. Aug 1999;63(8):644-8. [Medline].
Bagby GC Jr, Goldman RD, Newman HC, Means JF. Acute myocardial infarction due to childhood lymphoma. N Engl J Med. Aug 17 1972;287(7):338-40. [Medline].
Berenson GS, Srinivasan SR, Hunter SM, et al. Risk factors in early life as predictors of adult heart disease: the Bogalusa Heart Study. Am J Med Sci. Sep 1989;298(3):141-51. [Medline].
Berry CL. Myocardial ischaemia in infancy and childhood. J Clin Pathol. Jan 1967;20(1):38-41. [Medline].
Bex JP, Laborde F, Baillot F, Martelli H, Hazan E. [Myocardial infarction in an infant without coronary artery birth anomalies]. Arch Mal Coeur Vaiss. May 1980;73(5):535-7. [Medline].
Burns JC, Shike H, Gordon JB, et al. Sequelae of Kawasaki disease in adolescents and young adults. J Am Coll Cardiol. Jul 1996;28(1):253-7. [Medline].
Celermajer DS, Sholler GF, Howman-Giles R, Celermajer JM. Myocardial infarction in childhood: clinical analysis of 17 cases and medium term follow up of survivors. Br Heart J. Jun 1991;65(6):332-6. [Medline].
Coggon D, Margetts B, Barker DJ, et al. Childhood risk factors for ischaemic heart disease and stroke. Paediatr Perinat Epidemiol. Oct 1990;4(4):464-9. [Medline].
Dhillon R, Clarkson P, Donald AE, et al. Endothelial dysfunction late after Kawasaki disease. Circulation. Nov 1 1996;94(9):2103-6. [Medline].
Esterly JR, Oppenheimer EH. Some aspects of cardiac pathology in infancy and childhood. IV. Myocardial and coronary lesions in cardiac malformations. Pediatrics. Jun 1967;39(6):896-903. [Medline].
Fukuda T, Ishibashi M, Shinohara T, et al. Follow-up assessment of the collateral circulation in patients with Kawasaki disease who underwent dipyridamole stress technetium-99m tetrofosmin scintigraphy. Pediatr Cardiol. Sep-Oct 2005;26(5):558-64. [Medline].
Garcia RE, Moodie DS. Routine cholesterol surveillance in childhood. Pediatrics. Nov 1989;84(5):751-5. [Medline].
Gattorno M, Falcini F, Ravelli A, et al. Outcome of primary antiphospholipid syndrome in childhood. Lupus. 2003;12(6):449-53. [Medline].
Gunal N, Kara N, Cakar N, et al. Cardiac involvement in childhood polyarteritis nodosa. Int J Cardiol. Aug 8 1997;60(3):257-62. [Medline].
Haitas B, Baker SG, Meyer TE, et al. Natural history and cardiac manifestations of homozygous familial hypercholesterolaemia. Q J Med. Jul 1990;76(279):731-40. [Medline].
Hancock SL, Donaldson SS, Hoppe RT. Cardiac disease following treatment of Hodgkin's disease in children and adolescents. J Clin Oncol. Jul 1993;11(7):1208-15. [Medline].
Hawkins MM, Kingston JE, Kinnier Wilson LM. Late deaths after treatment for childhood cancer. Arch Dis Child. Dec 1990;65(12):1356-63. [Medline].
Isaka N, Nakano T. [Myocardial infarction in childhood]. Ryoikibetsu Shokogun Shirizu. 1996;(12):679-83. [Medline].
Israels SJ, Michelson AD. Antiplatelet therapy in children. Thromb Res. 2006;118(1):75-83. [Medline].
Kampmann C, Kuroczynski W, Trubel H, et al. Late results after PTCA for coronary stenosis after the arterial switch procedure for transposition of the great arteries. Ann Thorac Surg. Nov 2005;80(5):1641-6. [Medline].
Kondo C. Myocardial perfusion imaging in pediatric cardiology. Ann Nucl Med. Oct 2004;18(7):551-61. [Medline].
Kovacs CS, Sanfilippo AJ, Burggraf GW. Anterior wall myocardial infarction in a 15-year-old diabetic female associated with spontaneously resolving coronary thrombosis. Can J Cardiol. Sep 1992;8(7):733-6. [Medline].
Kreutzer U, Krulls-Munch J, Angres M, Schiessler A. [Successful resuscitation of a patient with ventricular fibrillation in Bland-White-Garland syndrome in adulthood. A case report]. Z Kardiol. Jul 1998;87(7):560-5. [Medline].
L'Ecuyer TJ, Poulik JM, Vincent JA. Myocardial infarction due to coronary abnormalities in pulmonary atresia with intact ventricular septum. Pediatr Cardiol. Jan-Feb 2001;22(1):68-70. [Medline].
Lindblade CL, Kirkpatrick EC, Ebenroth ES. Eosinophilic myocarditis presenting with pediatric myocardial infarction. Pediatr Cardiol. Jan-Feb 2006;27(1):162-5. [Medline].
Long WA, Willis PW 4th, Henry GW. Childhood traumatic infarction causing left ventricular aneurysm: diagnosis by two-dimensional echocardiography. J Am Coll Cardiol. Jun 1985;5(6):1478-83. [Medline].
Mavrogeni S, Papadopoulos G, Douskou M, et al. Magnetic resonance angiography, function and viability evaluation in patients with Kawasaki disease. J Cardiovasc Magn Reson. 2006;8(3):493-8. [Medline].
McMahon CJ, Nihill MR, Denfield S. Neoaortic root dilation associated with left coronary artery stenosis following arterial switch procedure. Pediatr Cardiol. Jan-Feb 2003;24(1):43-6. [Medline].
Monagle P. Thrombosis in pediatric cardiac patients. Semin Thromb Hemost. Dec 2003;29(6):547-55. [Medline].
Najean Y, Haguenauer O. Long-term (5 to 20 years) Evolution of nongrafted aplastic anemias. The Cooperative Group for the Study of Aplastic and Refractory Anemias. Blood. Dec 1 1990;76(11):2222-8. [Medline].
Neufeld EJ. Inherited dyslipidemias in childhood. Curr Opin Pediatr. Dec 1993;5(6):707-11. [Medline].
Neufeld HN, Blieden LC. Coronary artery disease in children. Postgrad Med J. Mar 1978;54(629):163-70. [Medline].
Newburger JW, Burns JC. Kawasaki disease. Vasc Med. 1999;4(3):187-202. [Medline].
Newburger JW, Takahashi M, Gerber MA, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. Dec 2004;114(6):1708-33. [Medline]. [Full Text].
Ou P, Mousseaux E, Azarine A, et al. Detection of coronary complications after the arterial switch operation for transposition of the great arteries: first experience with multislice computed tomography in children. J Thorac Cardiovasc Surg. Mar 2006;131(3):639-43. [Medline].
Pahl E, Naftel DC, Kuhn MA, et al. The impact and outcome of transplant coronary artery disease in a pediatric population: a 9-year multi-institutional study. J Heart Lung Transplant. Jun 2005;24(6):645-51. [Medline].
Pfafferott C, Wirtzfeld A, Permanetter B. Atypical Kawasaki syndrome: how many symptoms have to be present?. Heart. Dec 1997;78(6):619-21. [Medline]. [Full Text].
Radford DJ, Sondheimer HM, Williams GJ, Fowler RS. Mucocutaneous lymph node syndrome with coronary artery aneurysm. Am J Dis Child. Jun 1976;130(6):596-8. [Medline].
Schaison G, Jacquillat C, Lemercier N, Weil M, et al. [Acute leukemia in childhood: present status of 100 cases after 7 years of complete remission (author's transl)]. Bull Cancer. 1980;67(3):261-8. [Medline].
Senzaki H, Chen CH, Ishido H, et al. Arterial hemodynamics in patients after Kawasaki disease. Circulation. Apr 26 2005;111(16):2119-25. [Medline]. [Full Text].
Shaukat N, Ashraf S, Mebewu A, et al. Myocardial infarction in a young adult due to Kawasaki disease. A case report and review of the late cardiological sequelae of Kawasaki disease. Int J Cardiol. Jun 1993;39(3):222-6. [Medline].
Simoes MV, Felix PR, Marin-Neto JA. Acute myocardial infarction complicating the clinical course of dilated cardiomyopathy in childhood. Chest. Jan 1992;101(1):271-2. [Medline].
Smith BA, Grider DJ. Sudden death in a young adult: sequelae of childhood Kawasaki disease. Am J Emerg Med. Jul 1993;11(4):381-3. [Medline].
Srinivasan SR, Berenson GS. Serum apolipoproteins A-I and B as markers of coronary artery disease risk in early life: the Bogalusa Heart Study. Clin Chem. Jan 1995;41(1):159-64. [Medline].
Su JT, Chung T, Muthupillai R, et al. Usefulness of real-time navigator magnetic resonance imaging for evaluating coronary artery origins in pediatric patients. Am J Cardiol. Mar 1 2005;95(5):679-82. [Medline].
Takeuchi S, Imamura H, Katsumoto K, et al. New surgical method for repair of anomalous left coronary artery from pulmonary artery. J Thorac Cardiovasc Surg. Jul 1979;78(1):7-11. [Medline].
van Pelt NC, Wilson NJ, Lear G. Severe coronary artery disease in the absence of supravalvular stenosis in a patient with Williams syndrome. Pediatr Cardiol. Sep-Oct 2005;26(5):665-7. [Medline].
Vrsanska V, Bircak J. [Risk factors for cardiovascular diseases in childhood]. Bratisl Lek Listy. Sep 1989;90(9):670-5. [Medline].

