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Hamstring Injury Medication

  • Author: Herman Brad Ruiz, MD; Chief Editor: Craig C Young, MD  more...
Updated: Oct 22, 2015

Medication Summary

Although some inflammation may theoretically be desirable to facilitate clearing of necrotic tissue and to initiate healing, nonsteroidal anti-inflammatory drugs (NSAIDs) are usually started right away. However, NSAIDs are ideally used for only 3-7 days, given the evidence that their use may delay complete healing.

Acetaminophen or a narcotic may be administered in addition to an NSAID for most continuing pain. However, narcotics (eg, Vicodin) are usually reserved for those with serious injuries and extreme pain.

Some animal model studies show some evidence that anabolic steroids may aid in the healing of injured muscles. Animals that have been treated with anabolic steroids are able to generate greater forces through injured muscles than those that have not been treated with these agents. However, there is not enough evidence to recommend the use of anabolic steroids to promote faster healing.

Related Medscape topics:

Resource Center Adverse Drug Events Reporting

Resource Center Pain Management: Advanced Approaches to Chronic Pain Management

Resource Center Pain Management: Pharmacologic Approaches


Nonsteroidal Anti-inflammatory Agents

Class Summary

NSAIDs have analgesic and antipyretic activities. The mechanism of action of these agents is not known, but NSAIDs may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation and various cell membrane functions. Treatment of pain tends to be patient specific.

Naproxen (Aleve, Anaprox, Naprelan, Naprosyn)


Relieves mild to moderate pain. Inhibits inflammatory reactions and pain probably by decreasing the activity of the enzyme cyclooxygenase, which results in decreased prostaglandin synthesis.



Class Summary

Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma or who have sustained injuries.

Acetaminophen (Feverall, Tempra, Tylenol)


DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, in those diagnosed with upper GI disease, or in those taking oral anticoagulants.

Hydrocodone bitartrate and acetaminophen (Vicodin, Vicodin ES)


Drug combination indicated for moderate to severe pain.

Contributor Information and Disclosures

Herman Brad Ruiz, MD Staff Physician, Department of Physical Medicine and Rehabilitation, Division of Orthopedics and Rehabilitation, Loyola University Medical School at Illinois

Herman Brad Ruiz, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, Physiatric Association of Spine, Sports and Occupational Rehabilitation, American Pain Society, Association of Academic Physiatrists

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Russell D White, MD Clinical Professor of Medicine, Clinical Professor of Orthopedic Surgery, Department of Community and Family Medicine, University of Missouri-Kansas City School of Medicine, Truman Medical Center-Lakewood

Russell D White, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Family Physicians, American Association of Clinical Endocrinologists, American College of Sports Medicine, American Diabetes Association, American Medical Society for Sports Medicine

Disclosure: Nothing to disclose.

Chief Editor

Craig C Young, MD Professor, Departments of Orthopedic Surgery and Community and Family Medicine, Medical Director of Sports Medicine, Medical College of Wisconsin

Craig C Young, MD is a member of the following medical societies: American Academy of Family Physicians, American College of Sports Medicine, American Medical Society for Sports Medicine, Phi Beta Kappa

Disclosure: Nothing to disclose.

Additional Contributors

Joseph P Garry, MD, FACSM, FAAFP Associate Professor, Department of Family Medicine and Community Health, University of Minnesota Medical School

Joseph P Garry, MD, FACSM, FAAFP is a member of the following medical societies: American Academy of Family Physicians, American Medical Society for Sports Medicine, Minnesota Medical Association, American College of Sports Medicine

Disclosure: Nothing to disclose.

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