Hamstring Injury Medication
- Author: Herman Brad Ruiz, MD; Chief Editor: Craig C Young, MD more...
Although some inflammation may theoretically be desirable to facilitate clearing of necrotic tissue and to initiate healing, nonsteroidal anti-inflammatory drugs (NSAIDs) are usually started right away. However, NSAIDs are ideally used for only 3-7 days, given the evidence that their use may delay complete healing.
Acetaminophen or a narcotic may be administered in addition to an NSAID for most continuing pain. However, narcotics (eg, Vicodin) are usually reserved for those with serious injuries and extreme pain.
Some animal model studies show some evidence that anabolic steroids may aid in the healing of injured muscles. Animals that have been treated with anabolic steroids are able to generate greater forces through injured muscles than those that have not been treated with these agents. However, there is not enough evidence to recommend the use of anabolic steroids to promote faster healing.
Related Medscape topics:
Resource Center Adverse Drug Events Reporting
Resource Center Pain Management: Advanced Approaches to Chronic Pain Management
Resource Center Pain Management: Pharmacologic Approaches
Nonsteroidal Anti-inflammatory Agents
NSAIDs have analgesic and antipyretic activities. The mechanism of action of these agents is not known, but NSAIDs may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation and various cell membrane functions. Treatment of pain tends to be patient specific.
Relieves mild to moderate pain. Inhibits inflammatory reactions and pain probably by decreasing the activity of the enzyme cyclooxygenase, which results in decreased prostaglandin synthesis.
Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma or who have sustained injuries.
DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, in those diagnosed with upper GI disease, or in those taking oral anticoagulants.
Drug combination indicated for moderate to severe pain.
Davis KW. Imaging of the hamstrings. Semin Musculoskelet Radiol. 2008 Mar. 12(1):28-41. [Medline].
Reid DC. Soft tissue injuries of the thigh. Sports Injury Assessment and Rehabilitation. Philadelphia, Pa: Churchill Livingstone; 1992. 551-71.
Sarimo J, Lempainen L, Mattila K, Orava S. Complete proximal hamstring avulsions: a series of 41 patients with operative treatment. Am J Sports Med. 2008 Jun. 36(6):1110-5. [Medline].
Sallay PI, Friedman RL, Coogan PG, Garrett WE. Hamstring muscle injuries among water skiers. Functional outcome and prevention. Am J Sports Med. 1996 Mar-Apr. 24(2):130-6. [Medline].
Askling CM, Tengvar M, Saartok T, Thorstensson A. Proximal hamstring strains of stretching type in different sports: injury situations, clinical and magnetic resonance imaging characteristics, and return to sport. Am J Sports Med. 2008 Apr 30. epub ahead of print. [Medline].
Croisier JL, Ganteaume S, Binet J, Genty M, Ferret JM. Strength imbalances and prevention of hamstring injury in professional soccer players: a prospective study. Am J Sports Med. 2008 Apr 30. epub ahead of print. [Medline].
Clanton TO, Coupe KJ. Hamstring strains in athletes: diagnosis and treatment. J Am Acad Orthop Surg. 1998 Jul-Aug. 6(4):237-48. [Medline].
Hoskins W, Pollard H. The management of hamstring injury-- part 1: issues in diagnosis. Man Ther. 2005 May. 10(2):96-107. [Medline].
Levine WN, Bergfeld JA, Tessendorf W, Moorman CT 3rd. Intramuscular corticosteroid injection for hamstring injuries. A 13-year experience in the National Football League. Am J Sports Med. 2000 May-Jun. 28(3):297-300. [Medline].
Elliott MC, Zarins B, Powell JW, Kenyon CD. Hamstring muscle strains in professional football players: a 10-year review. Am J Sports Med. 2011 Apr. 39(4):843-50. [Medline].
Askling CM, Tengvar M, Thorstensson A. Acute hamstring injuries in Swedish elite football: a prospective randomised controlled clinical trial comparing two rehabilitation protocols. Br J Sports Med. 2013 Mar 27. [Medline].
Hrysomallis C. Injury incidence, risk factors and prevention in Australian rules football. Sports Med. 2013 May. 43(5):339-54. [Medline].
Malliaropoulos N, Isinkaye T, Tsitas K, Maffulli N. Reinjury after acute posterior thigh muscle injuries in elite track and field athletes. Am J Sports Med. 2011 Feb. 39(2):304-10. [Medline].
Opar DA, Williams MD, Shield AJ. Hamstring strain injuries: factors that lead to injury and re-injury. Sports Med. 2012 Mar 1. 42(3):209-26. [Medline].
Opar DA, Williams MD, Timmins RG, Dear NM, Shield AJ. Rate of torque and electromyographic development during anticipated eccentric contraction is lower in previously strained hamstrings. Am J Sports Med. 2013 Jan. 41 (1):116-25. [Medline].
Bucknor MD, Steinbach LS, Saloner D, Chin CT. Magnetic resonance neurography evaluation of chronic extraspinal sciatica after remote proximal hamstring injury: a preliminary retrospective analysis. J Neurosurg. 2014 Aug. 121 (2):408-14. [Medline].
Kujala UM, Orava S, Järvinen M. Hamstring injuries. Current trends in treatment and prevention. Sports Med. 1997 Jun. 23(6):397-404. [Medline].
Unger CL, Unger DA. Preventing and rehabilitating hamstring injuries. Athl Ther Today. 1997 May. 44-9.
Worrell TW. Factors associated with hamstring injuries. An approach to treatment and preventative measures. Sports Med. 1994 May. 17(5):338-45. [Medline].
Petersen J, Thorborg K, Nielsen MB, Budtz-Jørgensen E, Hölmich P. Preventive Effect of Eccentric Training on Acute Hamstring Injuries in Men's Soccer: A Cluster-Randomized Controlled Trial. Am J Sports Med. 2011 Nov. 39(11):2296-303. [Medline].