eMedicine Specialties > Sports Medicine > Lower Limb

Hamstring Injury: Treatment & Medication

Author: Herman Brad Ruiz, MD, Staff Physician, Department of Physical Medicine and Rehabilitation, Division of Orthopedics and Rehabilitation, Loyola University Medical School at Illinois
Coauthor(s): Syed M Zaffer, MD, Assistant Professor, Department of Physical Medicine and Rehabilitation, Rehabilitation Institute of Chicago, Northwestern University
Contributor Information and Disclosures

Updated: Jun 16, 2008

Treatment

Acute Phase

Rehabilitation Program

Physical Therapy

Treatment of hamstring injuries varies according to the severity of the injury. Patients with minor strains may progress quickly to strengthening exercises, whereas those with full-thickness ruptures require surgery. Up to 1 week after a minor injury, the focus of therapy is to limit pain, inflammation, and swelling. Rest, ice, compression, and elevation (RICE) are recommended. Elastic thigh bandages can be useful for compression. Icing for 20 minutes, 4 times per day, provides pain relief.

Most patients may begin active range of motion (AROM) exercises within their pain tolerance after 1-2 days. Individuals with more serious injuries benefit from immobilization in knee extension for 1-5 days to prevent contracture formation and further damage. Crutches enable ambulation while resting the injured leg.

After several days, most patients may begin pain-free submaximal isometrics, pool therapies, and upper-body exercises. Isometric exercises are performed at various knee angles in increments of 20°. Patients hold the contraction for 5-15 seconds, and perform 3 sets at each angle.

Related eMedicine topic:
Therapeutic Exercise

Medical Issues/Complications

If patients return to their usual activities too soon, delayed healing or reinjury may result. In more serious injuries, compartment syndrome can result from an extending hematoma. The most common symptom of compartment syndrome is increasing pain.

Surgical Intervention

Surgery is rarely performed for large hematomas; on the other hand, it is performed in more than 50% of cases of muscle belly tears, with consideration given to the patient's activity demands. However, surgery is generally indicated for bony avulsions only.

Consultations

In cases of severe hamstring injuries, consultation with a sports medicine specialist or an orthopedic surgeon may be indicated. Physiatrists may be consulted to oversee rehabilitative therapies and to help prevent further injuries.

Related eMedicine topic:
Adult Physiatric History and Examination

Recovery Phase

Rehabilitation Program

Physical Therapy

Generally, treatment 1-6 weeks postinjury focuses on patient strengthening, improving range of motion (ROM), and flexibility.

Passive static stretching may begin at this stage. Moist heat may be used to warm up the muscle tissues before stretching and exercising. Electrical stimulation may be used in conjunction with ice for added pain relief.

Being pain free throughout the entire ROM is not required before strengthening exercises may be initiated. The patient may exercise, preferably with a therapist, to strengthen the muscle within the available pain-free ROM.

Next, the patient begins isotonic exercises with resistance, increasing the program gradually as tolerated. As healing continues, high-speed, low-resistance isokinetic exercises are started. Resistance is increased gradually, while exercise speed is decreased. Over time, the patient progresses from concentric to eccentric strengthening exercises. Before the athlete returns to play, sports-specific training maximizes recovery and minimizes the chances for additional injury.

Related eMedicine topic:
Therapeutic Exercise

Medical Issues/Complications

Reinjury and delayed healing result if the therapy is too aggressive or if activity limitations are not followed.

Maintenance Phase

Rehabilitation Program

Physical Therapy

From 1 month postinjury onward, the patient continues stretching and strengthening exercises to maintain flexibility and an adequate hamstring-to-quadriceps strength ratio.

Medication

Although some inflammation may theoretically be desirable to facilitate clearing of necrotic tissue and to initiate healing, nonsteroidal anti-inflammatory drugs (NSAIDs) are usually started right away. However, NSAIDs are ideally used for only 3-7 days, given the evidence that their use may delay complete healing.

Acetaminophen or a narcotic may be administered in addition to an NSAID for most continuing pain. However, narcotics (eg, Vicodin) are usually reserved for those with serious injuries and extreme pain.

Some animal model studies show some evidence that anabolic steroids may aid in the healing of injured muscles. Animals that have been treated with anabolic steroids are able to generate greater forces through injured muscles than those that have not been treated with these agents. However, there is not enough evidence to recommend the use of anabolic steroids to promote faster healing.

Related eMedicine topics:
Anabolic Steroid Use and Abuse
Corticosteroid-Induced Myopathy
Toxicity, Acetaminophen
Toxicity, Narcotics
Toxicity, Nonsteroidal Anti-inflammatory Agents

Related Medscape topics:
Resource Center Adverse Drug Events Reporting
Resource Center Pain Management: Advanced Approaches to Chronic Pain Management
Resource Center Pain Management: Pharmacologic Approaches

Nonsteroidal Anti-inflammatory Agents

NSAIDs have analgesic and antipyretic activities. The mechanism of action of these agents is not known, but NSAIDs may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation and various cell membrane functions. Treatment of pain tends to be patient specific.


Naproxen (Aleve, Anaprox, Naprelan, Naprosyn)

Relieves mild to moderate pain. Inhibits inflammatory reactions and pain probably by decreasing the activity of the enzyme cyclooxygenase, which results in decreased prostaglandin synthesis.

Adult

250-500 mg PO bid; may increase to 1.5 g/d for limited periods; not to exceed 1.25 g/d

Pediatric

<2 years: Not established

>2 years: 2.5 mg/kg/dose PO; not to exceed 10 mg/kg/d

Coadministration with aspirin increases the risk of inducing serious NSAID-related adverse effects; probenecid may increase the concentrations and, possibly, the toxicity of NSAIDs; may decrease the effect of hydralazine, captopril, and beta-blockers; may decrease the diuretic effects of furosemide and thiazides; may increase PT duration when taking anticoagulants (instruct patients to watch for signs of bleeding); may increase the risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently

Pregnancy

B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals

D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus

Precautions

Acute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of the drug.

Analgesics

Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma or who have sustained injuries.


Acetaminophen (Feverall, Tempra, Tylenol)

DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, in those diagnosed with upper GI disease, or in those taking oral anticoagulants.

Adult

650-1000 mg PO q4-6h

Pediatric

15 mg/kg/dose PO q4h

Rifampin can reduce the analgesic effects of acetaminophen; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity.

Pregnancy

B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals

Precautions

Hepatotoxicity can occur in those with chronic alcoholism with various dose levels of acetaminophen; severe or recurrent pain or high or continued fever may indicate a serious illness.


Hydrocodone bitartrate and acetaminophen (Vicodin, Vicodin ES)

Drug combination indicated for moderate to severe pain.

Adult

1-2 tab or cap PO q4-6h prn

Pediatric

<12 years: 10-15 mg/kg/dose acetaminophen PO q4-6h prn; not to exceed 2.6 g/d acetaminophen

>12 years: 750 mg acetaminophen PO q4h; not to exceed 10 mg hydrocodone bitartrate per dose or 5 doses/24h

Coadministration with phenothiazines may decrease the analgesic effects; toxicity increases with CNS depressants or tricyclic antidepressants

Documented hypersensitivity; elevated intracranial pressure

Pregnancy

C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus

Precautions

The tablets contain metabisulfite, which may cause allergic reactions; caution in the presence of severe renal or hepatic dysfunction

More on Hamstring Injury

Overview: Hamstring Injury
Differential Diagnoses & Workup: Hamstring Injury
Treatment & Medication: Hamstring Injury
Follow-up: Hamstring Injury
References

References

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  3. Sarimo J, Lempainen L, Mattila K, Orava S. Complete proximal hamstring avulsions: a series of 41 patients with operative treatment. Am J Sports Med. Jun 2008;36(6):1110-5. [Medline].

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  5. Askling CM, Tengvar M, Saartok T, Thorstensson A. Proximal hamstring strains of stretching type in different sports: injury situations, clinical and magnetic resonance imaging characteristics, and return to sport. Am J Sports Med. Apr 30 2008;epub ahead of print. [Medline].

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Further Reading

Keywords

hamstring strain, hamstring pull, lower extremity injury, lower-extremity injury

Contributor Information and Disclosures

Author

Herman Brad Ruiz, MD, Staff Physician, Department of Physical Medicine and Rehabilitation, Division of Orthopedics and Rehabilitation, Loyola University Medical School at Illinois
Herman Brad Ruiz, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Pain Society, Association of Academic Physiatrists, and Physiatric Association of Spine, Sports and Occupational Rehabilitation
Disclosure: Nothing to disclose.

Coauthor(s)

Syed M Zaffer, MD, Assistant Professor, Department of Physical Medicine and Rehabilitation, Rehabilitation Institute of Chicago, Northwestern University
Syed M Zaffer, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation and Association of Academic Physiatrists
Disclosure: Nothing to disclose.

Medical Editor

Joseph P Garry, MD, Director of Sports Medicine and Sports Medicine Fellowship, Associate Professor of Family Medicine and Exercise and Sport Science, Department of Family Medicine, East Carolina University Brody School of Medicine
Joseph P Garry, MD is a member of the following medical societies: American Academy of Family Physicians, American College of Sports Medicine, American Heart Association, American Medical Society for Sports Medicine, North American Primary Care Research Group, and North Carolina Medical Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Russell D White, MD, Professor of Medicine, Department of Community and Family Medicine, University of Missouri-Kansas City School of Medicine, Truman Medical Center Lakewood
Disclosure: Nothing to disclose.

CME Editor

Jon B Whitehurst, MD, Clinical Instructor of Surgery, University of Illinois College of Medicine; Partner and Executive Board Member, Rockford Orthopedic Associates; Orthopedic Chairman, Rockford Memorial Hospital
Jon B Whitehurst, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Orthopaedic Society for Sports Medicine, and Arthroscopy Association of North America
Disclosure: Nothing to disclose.

Chief Editor

Craig C Young, MD, Professor, Departments of Orthopedic Surgery and Community and Family Medicine, Medical Director of Sports Medicine, Sports Medicine Fellowship Director, Medical College of Wisconsin
Craig C Young, MD is a member of the following medical societies: American Academy of Family Physicians, American College of Sports Medicine, American Medical Society for Sports Medicine, Phi Beta Kappa, and Wilderness Medical Society
Disclosure: Nothing to disclose.

 
 
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