Pediatric Attention Deficit Hyperactivity Disorder Follow-up

  • Author: Zainab P Contractor, MD; Chief Editor: Caroly Pataki, MD   more...
 
Updated: Jan 25, 2012
 

Further Outpatient Care

Follow-up for attention deficit hyperactivity disorder (ADHD), previously termed attention deficit disorder (ADD), varies and depends on the patient's profile, the clinician's experience, and the access to healthcare providers.

After the patient's condition is stabilized, a follow-up frequency of every 6-12 weeks is often appropriate for the first year.

After that, patients whose conditions are stable may do best with visits every 4 months to assess their medications.

Psychotherapy may need to be continued for months to years.

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Inpatient & Outpatient Medications

See Medication.

See the Table.

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Complications

Coexisting neuropsychiatric disorders and learning disorders can complicate the diagnosis and treatment of ADHD (ADD). See History.

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Prognosis

The prognosis for patients with ADHD (ADD) is excellent if the following conditions are present:

  • The patient has no major comorbidity.
  • Medication management takes into account minor comorbidities and the great range of individual responses.
  • Patients and caregivers receive appropriate education about ADHD (ADD) and ADHD (ADD) management.
  • Adherence to therapy continues.
  • Any and all coexisting learning disabilities are diagnosed, and remediation is scheduled and undertaken.
  • Any and all coexisting emotional problems are investigated and treated appropriately by a primary care provider or the patient is referred to a mental health professional.
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Patient Education

Provide information about the pathophysiology in lay terms.

Provide information about complementary therapeutic approaches to medication (eg, involvement of education specialists, counseling or coaching, school accommodations, parent training).

Provide clinical medication information.

Include appropriate follow-up parameters.

Attend to administrative issues related to medication (eg, prescription writing and safety, compliance with state laws).

Provide emergency information.

Seek school accommodations.

Provide contact information for local and national support organizations.

Provide literature or written resources (eg, books, periodicals).

For excellent patient education resources, visit eMedicine's Mental Health and Behavior Center. Also, see eMedicine's patient education article Attention-Deficit/Hyperactivity Disorder.

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Contributor Information and Disclosures
Author

Zainab P Contractor, MD  Medical Director, The Affinity Center; Cincinnati, Ohio

Disclosure: Nothing to disclose.

Coauthor(s)

Christine A Mayhall, PhD  Clinical Psychologist, The Affinity Center

Christine A Mayhall, PhD is a member of the following medical societies: American Psychological Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Chet Johnson  MD, Center for Child Health and Development, Shiefelbusch Institute for Life Span Studies, University of Kansas; Professor and Chair of Pediatrics, University of Kansas Medical Center

Chet Johnson is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Carrie Sylvester, MD, MPH  Senior Child and Adolescent Psychiatrist, Sound Mental Health

Carrie Sylvester, MD, MPH is a member of the following medical societies: American Academy of Child and Adolescent Psychiatry

Disclosure: Nothing to disclose.

Chief Editor

Caroly Pataki, MD  Professor of Clinical Psychiatry and Behavioral Sciences, Department of Psychiatry, Division Chair, Child and Adolescent Psychiatry, Keck School of Medicine of the University of Southern California

Caroly Pataki, MD is a member of the following medical societies: American Academy of Child and Adolescent Psychiatry, New York Academy of Sciences, and Physicians for Social Responsibility

Disclosure: Nothing to disclose.

Additional Contributors

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author Susan Louisa Montauk, MD†,to the development and writing of this article.

References
  1. APA. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association Press; 1994:78-85.

  2. Spinelli S, Joel S, Nelson TE, Vasa RA, Pekar JJ, Mostofsky SH. Different neural patterns are associated with trials preceding inhibitory errors in children with and without attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. Jul 2011;50(7):705-715.e3. [Medline].

  3. Ducharme S, Hudziak JJ, Botteron KN, Albaugh MD, Nguyen TV, Karama S, et al. Decreased regional cortical thickness and thinning rate are associated with inattention symptoms in healthy children. J Am Acad Child Adolesc Psychiatry. Jan 2012;51(1):18-27.e2. [Medline].

  4. Brown TE. Brown ADD Scales. San Antonio, TX: Psychological Corp; 1996:5-6.

  5. Nigg JT, Lewis K, Edinger T, Falk M. Meta-analysis of attention-deficit/hyperactivity disorder or attention-deficit/hyperactivity disorder symptoms, restriction diet, and synthetic food color additives. J Am Acad Child Adolesc Psychiatry. Jan 2012;51(1):86-97.e8. [Medline].

  6. [Best Evidence] Blader JC, Schooler NR, Jensen PS, Pliszka SR, Kafantaris V. Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy. Am J Psychiatry. Dec 2009;166(12):1392-401. [Medline].

  7. Habel LA, Cooper WO, Sox CM, et al. ADHD medications and risk of serious cardiovascular events in young and middle-aged adults. JAMA. Dec 28 2011;306(24):2673-83. [Medline].

  8. Wilens TE, Bukstein O, Brams M, Cutler AJ, Childress A, Rugino T, et al. A controlled trial of extended-release guanfacine and psychostimulants for attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. Jan 2012;51(1):74-85.e2. [Medline].

  9. Elia J, Ambrosini PJ, Rapoport JL. Treatment of attention-deficit-hyperactivity disorder. N Engl J Med. Mar 11 1999;340(10):780-8. [Medline].

  10. Hunt RD, Paguin A, Payton K. An update on assessment and treatment of complex attention-deficit hyperactivity disorder. Pediatr Ann. Mar 2001;30(3):162-72. [Medline].

  11. Johnson TM. Evaluating the hyperactive child in your office: is it ADHD?. Am Fam Physician. Jul 1997;56(1):155-60, 168-70. [Medline].

  12. Millichap JG. Etiologic classification of attention-deficit/hyperactivity disorder. Pediatrics. Feb 2008;121(2):e358-65. [Medline].

  13. Nadeau KG, Littman E, Quinn P. Understanding Girls With AD/HD. Springfield, MD: Advantage Books; 2000.

  14. Ramchandani P, Joughin C, Zwi M. Attention deficit hyperactivity disorder in children. Clin Evid. Jun 2002;262-71. [Medline].

  15. Rappley MD. Clinical practice. Attention deficit-hyperactivity disorder. N Engl J Med. Jan 13 2005;352(2):165-73. [Medline].

  16. Reeves G, Schweitzer J. Pharmacological management of attention-deficit hyperactivity disorder. Expert Opin Pharmacother. Jun 2004;5(6):1313-20. [Medline].

  17. Spencer TJ, Biederman J, Wilen T. Pharmacotherapy of ADHD with antidepressants. In: Barkley RS, ed. Attention Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. 2nd ed. New York, NY: Guilford Press; 1998:552-63.

  18. Wolraich ML, ed. The Classification of Child and Adolescent Mental Diagnoses in Primary Care: Diagnostic and Statistical Manual for Primary Care (DSM-PC) Child. Elk Grove, IL: American Academy of Pediatrics; 1996.

  19. Wilens TE. Straight Talk about Psychiatric Medications for Kids. New York, NY: Guilford Press; 2002.

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Table 1. Pediatric Dosing of Stimulant Medications
MedicationInitial Pediatric DosePediatric Dosage Range and Maximum Dose*Common Pediatric Dose*Preparations
Methylphenidate immediate release (IR) (Ritalin, Methylin, generic)2.5-5 mg0.1-0.8 mg/kg/dose PO qd to 5 times/d; not to exceed 60 mg/d0.3-0.5 mg/kg/dose PO tid/qidAll preparations available as 5-mg, 10-mg, or 20-mg scored tabs; Methylin also available as 2.5-mg, 5-mg, or 10-mg chewable tab and PO solution (5 mg/5 mL and 10 mg/mL)
Methylphenidate sustained-release (SR) (Ritalin LA, Metadate CD)Convert from IR or use 10 mg.0.2-1.4 mg/kg/dose PO qd/tid; not to exceed 60 mg/d0.6-1 mg/kg/dose PO qd/bid10-mg, 20-mg, 30-mg, or 40-mg tabs (Metadate also has 50-mg and 60-mg tabs.); can be sprinkled into soft food (Do not cut, crush, or chew.)
Methylphenidate extended release (ER)‡ (Ritalin SR, Methylin ER, Metadate ER, generic SR)Convert from IR.0.2-1.4 mg/kg/dose PO qd/tid; not to exceed 60 mg/d0.6-1 mg/kg/dose PO qd/bid20-mg Spansules (Do not cut, crush, or chew.)
Methylphenidate OROS tablets (Concerta)Convert from IR or use 18 mg.0.3-2 mg/kg PO qd; not to exceed 54 mg/d0.8-1.6 mg/kg PO qd18-mg, 27-mg, 36-mg, and 54-mg tabs (Do not cut, crush, or chew.)
Methylphenidate transdermal patch (Daytrana)Convert from IR or use 10 mg (12.5 cm2 patch) released over 9 h and titrate up prn.0.3-2 mg/kg released over 9 h; not to exceed one 30-mg patch10-30 mg released over 9 h10-mg, 15-mg, 20-mg, 30-mg patches, applied to the hip
Dexmethylphenidate IR (Focalin)2.5-5-mg0.1-0.5 mg/kg/dose PO qd to qid; not to exceed 20 mg/d0.2-0.3 mg/kg/dose PO bid/tid2.5-mg, 5-mg, or 10-mg scored tabs (Do not cut, crush, or chew.)
Dexmethylphenidate extended release (Focalin-XR)5-10-mg0.2-1 mg/kg/dose PO qd to bid; not to exceed 20 mg/d0.4-0.6 mg/kg/dose PO qd/bid5-mg, 10-mg, or 20-mg scored tabs; can be sprinkled into soft food (Do not cut, crush, or chew.)
Dextroamphetamine (Dexedrine, Dextrostat)2.5-5 mg0.1-0.7 mg/kg/dose PO qd/qid; not to exceed 60 mg/d0.3-0.5 mg/kg/dose PO qd/tidDexedrine: 5-mg scored tabs; Dextrostat: 5-mg and 10-mg scored tabs
Dextroamphetamine Spansules (Dexedrine CR)5 mg0.1-0.75 mg/kg/dose PO qd/bid; not to exceed 60 mg/d0.3-0.6 mg/kg/dose PO qd/bid5-mg, 10-mg, or 15-mg Spansules; can be sprinkled into soft food (Do not cut, crush, or chew.)
Mixed amphetamine salts IR (Adderall, generic)2.5-5 mg0.1-0.7 mg/kg/dose PO qd/qid; not to exceed 40 mg/d0.3-0.5 mg/kg/dose PO tid/qid5-mg, 7.5-mg, 10-mg, 12.5-mg, 15-mg, 20-mg, or 30-mg scored tabs
Mixed amphetamine salt XR (Adderall-XR)Convert from IR or use 5-10 mg0.2-1.4 mg/kg/dose PO qd/tid



Not to exceed 30 mg/d



0.6-1 mg/kg/dose PO qd/bid5-mg, 10-mg, 15-mg, 20-mg, 25-mg, or 30-mg Spansules; can be sprinkled into soft food (Do not cut, crush, or chew.)
Lisdexamfetamine (Vyvanse)30 mg PO qam30-70 mg PO qamData limited (too early to tell)20-mg, 30-mg, 40-mg, 50-mg, 60-mg, or 70-mg caps (Swallow cap whole, sprinkle into soft food, or dissolve contents in glass of water and drink immediately.)
Note. In general, when the terms methylphenidate, Dexedrine, and Ritalin are used without abbreviations for extended-release preparations (eg, continuous release [CR], SR, osmotic-release oral system [OROS]), a short-acting, IR preparation is implied.



* Maximum pediatric dose suggested by the US Food and Drug Administration (FDA). Although some children benefit greatly from doses greater than these, benefit from use of either the lowest and highest ends of the dose range is uncommon.



†The methylphenidate patch contains a different total methylphenidate dose than the name implies because it is designed to last 12 hours (eg, 10-mg patch [patch size 12.5 cm2] delivers about 10 mg over 9 h [estimated delivery rate is 1.1 mg/h for this particular patch]). Delivery rate varies depending on patch size.



‡Many patients describe their experience with methylphenidate SR preparations as erratic and uncomfortable.



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