eMedicine Specialties > Sports Medicine > Lower Limb

Slipped Capital Femoral Epiphysis

Author: Kevin D Walter, MD, FAAP, Assistant Professor of Orthopedics and Pediatrics, Department of Pediatric Orthopaedics, Department of Pediatrics, Medical College of Wisconsin; Member of Children's Specialty Group of Children's Hospital of Wisconsin
Coauthor(s): David Y Lin, MD, Fellow, Department of Orthopedic Surgery, Section of Pediatrics, University of Tennessee Campbell Clinic; Evan Schwartz, MD, Director of Orthopedic Surgery, New York Medical College; Assistant Professor, St John's Queens Hospital, Department of Surgery, Albert Einstein School of Medicine
Contributor Information and Disclosures

Updated: Aug 25, 2008

Introduction

Background

Slipped capital femoral epiphysis (SCFE) is one of the most important pediatric and adolescent hip disorders encountered in medical practice.1,2,3,4 Although SCFE is a rare condition, an accurate diagnosis combined with immediate treatment is critical.5,6  Despite the fact that the underlying defect may be multifactorial (eg, mechanical and constitutional factors), SCFE represents a unique type of instability of the proximal femoral growth plate. Clinically, the patient may report hip pain, medial thigh pain, and/or knee pain; an acute or insidious onset of a limp; and decreased range of motion of the hip.

On plain radiographs, the femoral head is seen displaced, posteriorly and inferiorly in relation to the femoral neck and within the confines of the acetabulum.7 Treatment is primarily operative internal fixation. The goal is to prevent complications such as avascular necrosis (AVN).2,8,9,10

For excellent patient education resources, visit eMedicine's Foot, Ankle, Knee, and Hip Center and Sports Injury Center. Also, see eMedicine's patient education article Repetitive Motion Injuries.

Related eMedicine topics:
Avascular Necrosis, Femoral Head [in the Radiology section]
Femoral Head Avascular Necrosis [in the Sports Medicine section]
Slipped Capital Femoral Epiphysis [in the Orthopedic Surgery section]
Slipped Capital Femoral Epiphysis [in the Radiology section]

Related Medscape topics
Resource Center Exercise and Sports Medicine
Resource Center Joint Disorders
Specialty Site Orthopaedics
CME/CE Evidence-Based Pain Management Practices in Older Adults in Multiple Practice Settings: A Challenge of Translation
MR Imaging of Femoroacetabular Impingement

Frequency

United States

The overall incidence for SCFE in the United States is 10.8 cases per 100,000 children.11  The incidence rate in boys (13.35/100,000) is higher than in girls (8.07/100,000). When compared with white children, black children have a higher incidence rate at 3.94 times, and Hispanic children have a 2.54 times higher incidence rate.

There are higher rates per 100,000 children of SCFE in the Northeast (17.15) and West (12.70) than the Midwest (7.69) and South (8.12). There is also evidence that points to a seasonal variation in SCFE occurrence. In areas north of 40º latitude, 57.4% of SCFEs occurred during the summer, whereas in areas south of 40º latitude, 57.3% of SCFEs occurred during the winter months.11

SCFE mainly occurs between the ages of 10-16 years.1,11  There has been a slight downward trend for average ages over several years, with some data finding the average age for boys at 12.7 years and girls at 11.2 years. This change could be due to the phenomenon of children maturing at a younger age.

In general, about 20% of patients have bilateral involvement at the time of presentation. It is felt that an additional 20-40% will subsequently progress to bilateral slips. When the presentation is sequential, the second hip usually presents within 18 months of the first SCFE.12,13

There is an increased risk in children who are obese, as well as in children with other medical issues: hypothyroidism, low growth hormone level, pituitary tumors, craniopharyngioma, Down syndrome, renal osteodystrophy, and adiposogenital syndrome.

International

In a study by Benson et al, the investigators reexamined the incidence of SCFE in New Mexico (previous studies had reported almost a 5-fold lower incidence of SCFE in New Mexico compared with Connecticut). The discharge databases for the 11 major medical centers in New Mexico from 1995 to 2006 were analyzed by comparison with the 2000 New Mexico census data. The incidence data are reported as cases per 100,000 boys aged 10-17 years and girls aged 8-15 years, as per the earlier study data.14

The investigators found an incidence rate of SCFE in New Mexico for the study period was 5.99, which was a statistically significant change that was more than double the reported incidence in the 1960s (2.13). Obesity was noted as a patient factor that changed since 1971 (tripled), although the national incidence of SCFE appeared to have remained fairly constant at 10.8 per 100,000. Benson et al theorized that "increased obesity in children and improved access to pediatric orthopaedic evaluation may have contributed to a significant increase in reported incidence of SCFE in New Mexico."14

Functional Anatomy

SCFE results from a Salter-Harris type physeal fracture. In patients with SCFE, the epiphyseal growth plate is unusually widened, primarily due to expansion of the zone of hypertrophy. The hypertrophic zone, which constitutes 15-30% of the normal physis, can account for up to 80% of the width of the physeal plate in affected patients. Histologically, abnormal cartilage maturation, endochondral ossification, and perichondral ring instability occur. This leads to less organization of the normal cartilaginous columnar architecture. Slippage occurs through this weakened area.

The position of the proximal physis normally changes from horizontal to oblique during preadolescence and adolescence, redirecting hip forces from compression forces to shear forces. There is an association between femoral neck retroversion and a reduced neck-shaft angle with SCFE. These changes can increase the shear forces across the hip, leading to SCFE.15  Other concomitant findings in the hip include inflammatory synovitis and disorganized collagen fibrils with accumulations of proteoglycans and glycoproteins within the growth plate; however, whether these changes are a cause or a result of SCFE remains undetermined.

Clinical

History

  • Slipped capital femoral epiphysis (SCFE) is most common in the adolescent period (ie, boys aged 10-16 y, girls aged 12-14 y). Males have 2.4 times the risk compared with females.
  • The left hip is affected more commonly than the right.
  • Obesity is a risk factor because it places more shear forces around the proximal growth plate in the hip at risk.16,17
  • The duration, location, and radiation of pain are important, as is the ability to bear weight.
  • Genetics may play a role in SCFE because the rate of familial involvement is 5-7%, with a large variability in penetrance.
  • In patients younger than 10 years, SCFE is associated with metabolic endocrine disorders (eg, hypothyroidism, panhypopituitarism, hypogonadism, renal osteodystrophy, growth hormone abnormalities).1,18,19 Bilaterality is more common in these younger patients.
  • The chronicity of the condition should be determined.
    • Prodromal symptoms (eg, hip or knee pain, limp, decreased range of motion) for less than 3 weeks are deemed acute.
    • Prodromal symptoms for longer than 3 weeks are deemed chronic.
    • If a patient reports symptoms of greater than 3 weeks' duration but presents with an acute exacerbation of pain, limp, inability to bear weight, or decreased range of motion with or without an associated traumatic episode, the SCFE is categorized as acute on chronic.
    • Determine if a traumatic episode occurred.
  • It is important to determine if the lesion is stable or unstable.
    • "Stable" SCFEs allow the patient to ambulate with or without crutches.6
    • "Unstable" SCFEs do not allow the patient to ambulate at all; these cases carry a higher rate of complication, particularly of AVN.6

Physical

  • If a patient reports knee pain, always examine the hip, because knee pain may be referred pain from the hip via the obturator nerve.
  • Obesity increases a clinician's index of suspicion for SCFE.
  • Patients often hold their affected hip in passive external rotation.
  • Determine the patient's ability to bear weight (stable vs unstable).
  • If the patient is ambulatory, determine the his or her gait pattern:
    • Antalgic – Shortened stance phase on the affected side
    • Out-toeing
  • Always examine both hips. Assess the active and passive range of motion in both hips. In patients with unilateral complaints, this comparison allows the clinician to compare the affected and unaffected sides for differences. Internal and external rotation are best tested with the patient in the prone position with the knees flexed to 90 º.
    • If SCFE is present, the lower extremity may externally rotate and abduct with gentle passive hip flexion.
    • Internal rotation is decreased in nearly all hips with SCFE. Internal rotation is often painful.

More on Slipped Capital Femoral Epiphysis

Overview: Slipped Capital Femoral Epiphysis
Differential Diagnoses & Workup: Slipped Capital Femoral Epiphysis
Treatment & Medication: Slipped Capital Femoral Epiphysis
Follow-up: Slipped Capital Femoral Epiphysis
Multimedia: Slipped Capital Femoral Epiphysis
References

References

  1. Kehl DK. Slipped capital femoral epiphysis. In: Lovell WW, Winter RB, Morrissy RT, Weinstein SL, eds. Lovell & Winter's Pediatric Orthopaedics. 4th ed. Philadelphia, Pa: Lippincott, Williams & Wilkins; 1996.

  2. Katz DA. Slipped capital femoral epiphysis: the importance of early diagnosis. Pediatr Ann. Feb 2006;35(2):102-11. [Medline].

  3. Loder RT. Controversies in slipped capital femoral epiphysis. Orthop Clin North Am. Apr 2006;37(2):211-21, vii. [Medline].

  4. Frick SL. Evaluation of the child who has hip pain. Orthop Clin North Am. Apr 2006;37(2):133-40, v. [Medline].

  5. Peterson MD, Weiner DS, Green NE, Terry CL. Acute slipped capital femoral epiphysis: the value and safety of urgent manipulative reduction. J Pediatr Orthop. Sep-Oct 1997;17(5):648-54. [Medline].

  6. Loder RT, Richards BS, Shapiro PS, Reznick LR, Aronson DD. Acute slipped capital femoral epiphysis: the importance of physeal stability. J Bone Joint Surg Am. Aug 1993;75(8):1134-40. [Medline][Full Text].

  7. Klein A, Joplin RJ, Reidy JA, Hanelin J. Roentgenographic features of slipped capital femoral epiphysis. Am J Roentgenol Radium Ther Nucl Med. Sep 1951;66(3):361-74. [Medline].

  8. Uglow MG, Clarke NM. The management of slipped capital femoral epiphysis. J Bone Joint Surg Br. Jul 2004;86(5):631-5. [Medline].

  9. Crawford AH. Slipped capital femoral epiphysis. J Bone Joint Surg Am. Oct 1988;70(9):1422-7. [Medline][Full Text].

  10. Stanitski CL. Acute slipped capital femoral epiphysis: treatment alternatives. J Am Acad Orthop Surg. Mar 1994;2(2):96-106. [Medline].

  11. Lehmann CL, Arons RR, Loder RT, Vitale MG. The epidemiology of slipped capital femoral epiphysis: an update. J Pediatr Orthop. May-Jun 2006;26(3):286-90. [Medline].

  12. Riad J, Bajelidze G, Gabos PG. Bilateral slipped capital femoral epiphysis: predictive factors for contralateral slip. J Pediatr Orthop. Jun 2007;27(4):411-4. [Medline].

  13. Hägglund G, Hansson LI, Ordeberg G, Sandström S. Bilaterality in slipped upper femoral epiphysis. J Bone Joint Surg Br. Mar 1988;70(2):179-81. [Medline][Full Text].

  14. Benson EC, Miller M, Bosch P, Szalay EA. A new look at the incidence of slipped capital femoral epiphysis in new Mexico. J Pediatr Orthop. Jul-Aug 2008;28(5):529-33. [Medline].

  15. Zupanc O, Krizancic M, Daniel M, et al. Shear stress in epiphyseal growth plate is a risk factor for slipped capital femoral epiphysis. J Pediatr Orthop. Jun 2008;28(4):444-51. [Medline].

  16. Brenkel IJ, Dias JJ, Davies TG, Iqbal SJ, Gregg PJ. Hormone status in patients with slipped capital femoral epiphysis. J Bone Joint Surg Br. Jan 1989;71(1):33-8. [Medline][Full Text].

  17. Pritchett JW, Perdue KD. Mechanical factors in slipped capital femoral epiphysis. J Pediatr Orthop. Jul-Aug 1988;8(4):385-8. [Medline].

  18. Wells D, King JD, Roe TF, Kaufman FR. Review of slipped capital femoral epiphysis associated with endocrine disease. J Pediatr Orthop. Sep-Oct 1993;13(5):610-4. [Medline].

  19. Zubrow AB, Lane JM, Parks JS. Slipped capital femoral epiphysis occurring during treatment for hypothyroidism. J Bone Joint Surg Am. Mar 1978;60(2):256-8. [Medline][Full Text].

  20. Tins B, Cassar-Pullicino V, McCall I. The role of pre-treatment MRI in established cases of slipped capital femoral epiphysis. Eur J Radiol. Apr 23 2008;epub ahead of print. [Medline].

  21. Aronson DD, Carlson WE. Slipped capital femoral epiphysis. A prospective study of fixation with a single screw. J Bone Joint Surg Am. Jul 1992;74(6):810-9. [Medline][Full Text].

  22. Ward WT, Stefko J, Wood KB, Stanitski CL. Fixation with a single screw for slipped capital femoral epiphysis. J Bone Joint Surg Am. Jul 1992;74(6):799-809. [Medline][Full Text].

  23. Kocher MS, Bishop JA, Hresko MT, et al. Prophylactic pinning of the contralateral hip after unilateral slipped capital femoral epiphysis. J Bone Joint Surg Am. Dec 2004;86-A(12):2658-65. [Medline][Full Text].

  24. Weiner DS, Weiner S, Melby A, Hoyt WA Jr. A 30-year experience with bone graft epiphysiodesis in the treatment of slipped capital femoral epiphysis. J Pediatr Orthop. Mar 1984;4(2):145-52. [Medline].

  25. Betz RR, Steel HH, Emper WD, Huss GK, Clancy M. Treatment of slipped capital femoral epiphysis. Spica-cast immobilization. J Bone Joint Surg Am. Apr 1990;72(4):587-600. [Medline][Full Text].

  26. Al-Nammari SS, Tibrewal S, Britton EM, Farrar NG. Management outcome and the role of manipulation in slipped capital femoral epiphysis. J Orthop Surg (Hong Kong). Apr 2008;16(1):131; author reply 131-2. [Medline].

  27. Harris WH. Etiology of osteoarthritis of the hip. Clin Orthop Relat Res. Dec 1986;213:20-33. [Medline].

  28. Kelsey JL, Keggi KJ, Southwick WO. The incidence and distribution of slipped capital femoral epiphysis in Connecticut and Southwestern United States. J Bone Joint Surg Am. Sep 1970;52(6):1203-16. [Medline][Full Text].

  29. Krahn TH, Canale ST, Beaty JH, Warner WC, Lourenço P. Long-term follow-up of patients with avascular necrosis after treatment of slipped capital femoral epiphysis. J Pediatr Orthop. Mar-Apr 1993;13(2):154-8. [Medline].

  30. Rubin LE, Galante NJ, Smith BG, DeLuca PA. Direct intraosseous pressure monitoring of the femoral head during surgery for slipped capital femoral epiphysis. Orthopedics. Jul 2008;31(7):663-6. [Medline].

Further Reading

Keywords

slipped capital femoral epiphysis, hip pain, pain in hip, hip joint pain, SCFE, slipped epiphysis, femoral pain, hip disorder, slipped hip, adolescent hip disorder, femoral head displacement, Salter-Harris physeal fracture, Salter-Harris fracture, femoral head avascular necrosis

Contributor Information and Disclosures

Author

Kevin D Walter, MD, FAAP, Assistant Professor of Orthopedics and Pediatrics, Department of Pediatric Orthopaedics, Department of Pediatrics, Medical College of Wisconsin; Member of Children's Specialty Group of Children's Hospital of Wisconsin
Kevin D Walter, MD, FAAP is a member of the following medical societies: American Academy of Pediatrics and American Medical Society for Sports Medicine
Disclosure: Nothing to disclose.

Coauthor(s)

David Y Lin, MD, Fellow, Department of Orthopedic Surgery, Section of Pediatrics, University of Tennessee Campbell Clinic
David Y Lin, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons
Disclosure: Nothing to disclose.

Evan Schwartz, MD, Director of Orthopedic Surgery, New York Medical College; Assistant Professor, St John's Queens Hospital, Department of Surgery, Albert Einstein School of Medicine
Evan Schwartz, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons and American Orthopaedic Society for Sports Medicine
Disclosure: Nothing to disclose.

Medical Editor

Anthony J Saglimbeni, MD, Staff Physician, Family Practice Residency, Medical Director, Center for Sports Medicine, O'Connor Hospital; Private Practice
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

CME Editor

Jon B Whitehurst, MD, Clinical Instructor of Surgery, University of Illinois College of Medicine; Partner and Executive Board Member, Rockford Orthopedic Associates; Orthopedic Chairman, Rockford Memorial Hospital
Jon B Whitehurst, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Orthopaedic Society for Sports Medicine, and Arthroscopy Association of North America
Disclosure: Nothing to disclose.

Chief Editor

Craig C Young, MD, Professor, Departments of Orthopedic Surgery and Community and Family Medicine, Medical Director of Sports Medicine, Sports Medicine Fellowship Director, Medical College of Wisconsin
Craig C Young, MD is a member of the following medical societies: American Academy of Family Physicians, American College of Sports Medicine, American Medical Society for Sports Medicine, Phi Beta Kappa, and Wilderness Medical Society
Disclosure: Nothing to disclose.

 
 
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