Childhood Disintegration Disorder Follow-up

  • Author: Bettina E Bernstein, DO; Chief Editor: Caroly Pataki, MD   more...
 
Updated: Nov 23, 2009
 

Further Inpatient Care

Generally, inpatient care is unnecessary for childhood disintegrative disorder in the absence of the following:

  • An associated medical condition (eg, seizures, head injury)
  • A severe psychiatric problem (eg, behavioral disturbances that warrant closer observation, supervision, and/or stabilization)
  • NMS
  • Alteration of electrolytes levels (such as hyponatremia related to treatment with SSRIs or atypical antipsychotics), which may need to be treated with intravenous therapy
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Prognosis

  • The prognosis of childhood disintegrative disorder has been considered guarded; however, more data are needed since this disorder is so rare.[2]
  • Children with moderate-to-severe mental retardation or lack of communicative language have a worse prognosis than those with usual IQ and communicative language.[2, 26]
  • The disorder is lifelong, and the social, communicative, and behavioral difficulties tend to impair function throughout life.[2, 46]
  • Risk of seizures increases with age and peaks at adolescence. Concomitant administration of SSRIs (eg, fluoxetine) and low-dose high-potency neuroleptics (eg, haloperidol) tends to lower the seizure threshold (as does alcohol), which may increase the likelihood of seizures.[34]
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Patient Education

  • Educating the patient, family, and/or caregivers is important so that an understanding of the nature of childhood disintegrative disorder and its natural history is known.
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Contributor Information and Disclosures
Author

Bettina E Bernstein, DO  Assistant Professor, Department of Psychiatry, Philadelphia College of Osteopathic Medicine; Private Practice at the Wynnewood House; Consultant, Child Guidance Resource Centers, Education Program, Clinical Affiliate, Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, Psychiatric Consultant, Ridley School District, Easttown Tredyffrin School District

Bettina E Bernstein, DO is a member of the following medical societies: American Academy of Child and Adolescent Psychiatry and American Psychiatric Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Carol Diane Berkowitz, MD  Executive Vice Chair, Department of Pediatrics, Professor, Harbor-University of California at Los Angeles Medical Center

Carol Diane Berkowitz, MD is a member of the following medical societies: Alpha Omega Alpha, Ambulatory Pediatric Association, American Academy of Pediatrics, American College of Emergency Physicians, American Medical Association, American Pediatric Society, and North American Society for Pediatric and Adolescent Gynecology

Disclosure: Nothing to disclose.

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Pharmacy Editor, eMedicine

Disclosure: Nothing to disclose.

Caroly Pataki, MD  Professor of Clinical Psychiatry and Behavioral Sciences, Department of Psychiatry, Division Chair, Child and Adolescent Psychiatry, Director of Training, Child and Adolescent Psychiatry Residency Program, University of Southern California Keck School of Medicine

Caroly Pataki, MD is a member of the following medical societies: American Academy of Child and Adolescent Psychiatry, New York Academy of Sciences, and Physicians for Social Responsibility

Disclosure: Nothing to disclose.

Daniel Rauch, MD, FAAP  Director, Pediatric Hospitalist Program, Associate Professor, Department of Pediatrics, New York University School of Medicine

Daniel Rauch, MD, FAAP is a member of the following medical societies: Ambulatory Pediatric Association, American Academy of Pediatrics, and Society of Hospital Medicine

Disclosure: Baxter Honoraria Consulting

Chief Editor

Caroly Pataki, MD  Professor of Clinical Psychiatry and Behavioral Sciences, Department of Psychiatry, Division Chair, Child and Adolescent Psychiatry, Director of Training, Child and Adolescent Psychiatry Residency Program, University of Southern California Keck School of Medicine

Caroly Pataki, MD is a member of the following medical societies: American Academy of Child and Adolescent Psychiatry, New York Academy of Sciences, and Physicians for Social Responsibility

Disclosure: Nothing to disclose.

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