Posttraumatic Stress Disorder in Children
- Author: Roy H Lubit, MD, PhD; Chief Editor: Caroly Pataki, MD more...
Background
Posttraumatic stress disorder (PTSD) in children and adolescents occurs as a result of a child's exposure to one or more traumatic events that were life-threatening or perceived to be likely to cause serious injury to self or others. In addition, the child or adolescent must have responded with intense fear, helplessness, or horror. Traumatic events can take many forms, including physical or sexual assaults, natural disasters, traumatic death of a loved one, or emotional abuse or neglect. Severe emotional trauma has widespread effects on children's development. These effects include undermining children's sense of security in a reasonable and safe world in which they can grow and explore, as well as causing a child to not believe that their parents can protect them from harm. The premature destruction of these beliefs can have profound negative consequences on development.
Traumatized children and adolescents are frequently preoccupied with danger and vulnerability, sometimes leading to misperceptions of danger, even in situations that are not threatening. Multiple researchers (eg, Kardiner, van der Kolk[1] ) note that, once posttraumatic stress symptoms emerge, PTSD leads to neurophysiologic correlates that impact brain function in developing children and adolescents.
In 1980, the term PTSD first came into existence in the Diagnostic and Statistical Manual of Mental Disorders, Third Edition (DSM-III).[2] Only in 1987 did the DSM series make reference to traumatized children. The first major studies of the effects of large traumas on children were Bloch's 1956 study of the effect of a tornado in Mississippi, Lacey's 1972 study of the effects of an avalanche on a Welsh school, Newman's 1976 work on the Buffalo Creek disaster,[3] and Terr's 1979 research on the Chowchilla bus kidnapping.[4]
Pathophysiology
Evidence indicates a genetic predisposition for PTSD, suggesting that it may be linked to the individual's temperament and to reactivity of the hypothalamic pituitary axis.
Epidemiology
Frequency
United States
Lifetime prevalence of PTSD is 8%.[5] The incidence and course of PTSD vary and depend on various factors, including the type of trauma, the proximity to the stressor, and the reaction of the child's parents. After being kidnapped, witnessing the death of a parent, or suffering domestic violence, the rate of PTSD may be 95-100%. Following a sniper attack at school, 40% of children experienced moderate-to-severe PTSD. In one study of children in foster care, 64% who had experienced sexual abuse had PTSD, and 42% who had experienced physical abuse fulfilled the PTSD criteria. Moreover, 18% of the children who were not abused also met PTSD criteria, presumably because they had witnessed violence.
International
The prevalence in a location overwhelmingly depends on the endemicity of violence in the region.
Mortality/Morbidity
Alone, PTSD is not a fatal disorder. Nevertheless, it frequently leads to conduct disorder, substance abuse, depression, and risk-taking that poses considerable danger.
PTSD has a considerable morbidity rate, particularly for children. In addition to the symptoms of numbing, hyperarousal, and recollections of the event that adults experience, children suffer from a decreased ability to participate in the normal academic and social activities of childhood. Therefore, a traumatic event can send a child down a new developmental path, one that is less favorable than the one the child was previously on.
A host of emotional and behavioral problems frequently arise as a result of PTSD and are not part of the criteria for categorical diagnosis. These include disruptive behavior disorders, eating disorders, sexual acting out, other risk-taking activities, depression, the full range of anxiety disorders, dissociation, mood lability, violence, and difficulty concentrating.
Studies of adults who were sexually or physically abused as children demonstrate significantly higher rates of PTSD (72-100%) than studies of children who were abused (21-55%). This finding indicates that the full impact of abuse may not be experienced until a child reaches adulthood, engages in adult relationships and responsibilities, and develops more sophisticated cognitive capabilities.
Race
No major racial predominance is observed; however, PTSD is more common among individuals in low socioeconomic groups and among those living in areas in which violence is endemic.
Sex
PTSD is more common in women than in men.
Age
PTSD occurs in people of all ages, but younger and elderly persons are the most vulnerable.
van der Kolk BA, McFarlane AC, Weisaeth L, eds. Traumatic Stress. Guilford Press; 1996.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Revised Fourth Edition. American Psychiatric Press, Inc; 1994.
Newman CJ. Disaster at Buffalo Creek. Children of disaster: clinical observations at Buffalo Creek. Am J Psychiatry. Mar 1976;306-12. [Medline].
Terr LC. Children of Chowchilla: a study of psychic trauma. Psychoanal Study Child. 1979;34:547-623. [Medline].
Keane TM, Marshall AD, Taft CT. Posttraumatic stress disorder: etiology, epidemiology, and treatment outcome. Annu Rev Clin Psychol. 2006;2:161-97. [Medline].
Scheeringa MS, Zeanah CH, Drell MJ, Larrieu JA. Two approaches to the diagnosis of posttraumatic stress disorder in infancy and early childhood. J Am Acad Child Adolesc Psychiatry. Feb 1995;34(2):191-200. [Medline].
Scheeringa MS, Zeanah CH, Myers L, Putnam FW. New findings on alternative criteria for PTSD in preschool children. J Am Acad Child Adolesc Psychiatry. May 2003;42(5):561-70. [Medline].
Lubit R, Hartwell N, van Gorp WG, Eth S. Forensic evaluation of trauma syndromes in children. Child Adolesc Psychiatr Clin N Am. Oct 2002;11(4):823-57. [Medline].
Carrion VG, Weems CF, Reiss AL. Stress predicts brain changes in children: a pilot longitudinal study on youth stress, posttraumatic stress disorder, and the hippocampus. Pediatrics. Mar 2007;119(3):509-16. [Medline].
Cohen JA, Mannarino AP, Iyengar S. Community treatment of posttraumatic stress disorder for children exposed to intimate partner violence: a randomized controlled trial. Arch Pediatr Adolesc Med. Jan 2011;165(1):16-21. [Medline].
Terr LC. Childhood traumas: an outline and overview. Am J Psychiatry. Jan 1991;148(1):10-20. [Medline].
American Academy of Child and Adolescent Psychiatry Work Group on Quality Issues. Practice parameters for the assessment and treatment of children and adolescents with posttraumatic stress disorder. J Am Acad Child Adolesc Psychiatry. Oct 1998;37(10 Suppl):4S-26S. [Medline].
Black D, Newman M. Psychological Trauma: A Developmental Approach. London, England: Royal College of Psychiatrists; 1998.
Carrion VG, Weems CF, Ray R, Reiss AL. Toward an empirical definition of pediatric PTSD: the phenomenology of PTSD symptoms in youth. J Am Acad Child Adolesc Psychiatry. Feb 2002;41(2):166-73. [Medline].
Cicchetti D, Toth SL. Child maltreatment. Annu Rev Clin Psychol. 2005;1:409-38. [Medline].
Cohen JA, Deblinger E, Mannarino AP, Steer RA. A multisite, randomized controlled trial for children with sexual abuse-related PTSD symptoms. J Am Acad Child Adolesc Psychiatry. Apr 2004;43(4):393-402. [Medline].
Cohen JA, Mannarino AP, Perel JM, Staron V. A pilot randomized controlled trial of combined trauma-focused CBT and sertraline for childhood PTSD symptoms. J Am Acad Child Adolesc Psychiatry. Jul 2007;46(7):811-9. [Medline].
Copeland WE, Keeler G, Angold A, Costello EJ. Traumatic events and posttraumatic stress in childhood. Arch Gen Psychiatry. May 2007;64(5):577-84. [Medline].
Donnelly CL, Amaya-Jackson L, March JS. Psychopharmacology of pediatric posttraumatic stress disorder. J Child Adolesc Psychopharmacol. 1999;9(3):203-20. [Medline].
Eth S. PTSD in Children and Adolescents. Washington, DC: APA Press; 2001.
Harmon RJ, Riggs PD. Clonidine for posttraumatic stress disorder in preschool children. J Am Acad Child Adolesc Psychiatry. Sep 1996;35(9):1247-9. [Medline].
Hsu CC, Chong MY, Yang P, Yen CF. Posttraumatic stress disorder among adolescent earthquake victims in Taiwan. J Am Acad Child Adolesc Psychiatry. Jul 2002;41(7):875-81. [Medline].
Kassam-Adams N, Winston FK. Predicting child PTSD: the relationship between acute stress disorder and PTSD in injured children. J Am Acad Child Adolesc Psychiatry. Apr 2004;43(4):403-11. [Medline].
Langeland W, Olff M. Psychobiology of posttraumatic stress disorder in pediatric injury patients: A review of the literature. Neurosci Biobehav Rev. 2007;[Medline].
Lubit R, Rovine D, Defrancisci L, Eth S. Impact of trauma on children. J Psychiatr Pract. Mar 2003;9(2):128-38. [Medline].
Lubit, R. Impact of trauma on children. In: Chang. Child and Adolescent Psychiatry: Intermediate Text. Lippincott, Williams and Wilkins; 2005.
Margaret E Blaustein and Kristine M Kinniburgh. Treating Traumatic Stress in Children and Adolescents: How to Foster Resilience through Attachment, Self-Regulation, and Competency. Guilford Press; 2010.
Martini RD. PTSD in children and adolescents (review of psychiatry series, volume 20). J Am Acad Child Adolesc Psych. Feb 2002;41(2):230-32.
Ohan JL, Myers K, Collett BR. Ten-year review of rating scales. IV: scales assessing trauma and its effects. J Am Acad Child Adolesc Psychiatry. Dec 2002;41(12):1401-22. [Medline].
Pelcovitz D, Kaplan S. Post-traumatic stress disorder in children and adolescents. Child Adolesc Psychiatr Clin N Am. 1996;5:449-496.
Perrin S, Smith P, Yule W. The assessment and treatment of Post-traumatic Stress Disorder in children and adolescents. J Child Psychol Psychiatry. Mar 2000;41(3):277-89. [Medline].
Pervanidou P, Kolaitis G, Charitaki S, et al. The natural history of neuroendocrine changes in pediatric posttraumatic stress disorder (PTSD) after motor vehicle accidents: progressive divergence of noradrenaline and cortisol concentrations over time. Biol Psychiatry. Nov 15 2007;62(10):1095-102. [Medline].
Pfefferbaum B. Posttraumatic stress disorder in children: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. Nov 1997;36(11):1503-11. [Medline].
Porter DM, Bell CC. The use of clonidine in post-traumatic stress disorder. J Natl Med Assoc. Aug 1999;91(8):475-7. [Medline].
Practice parameters for the assessment and treatment of children and adolescents with posttraumatic stress disorder. J Am Acad Child Adolesc Psychiatry. Oct 1998;37(10 Suppl):4S-26S. [Medline].
Pynoos RS, Steinberg AM, Piacentini JC. A developmental psychopathology model of childhood traumatic stress and intersection with anxiety disorders. Biol Psychiatry. Dec 1 1999;46(11):1542-54. [Medline].
Saxe G, Chawla N, Stoddard F, et al. Child Stress Disorders Checklist: a measure of ASD and PTSD in children. J Am Acad Child Adolesc Psychiatry. Aug 2003;42(8):972-8. [Medline].
Simon GE, Savarino J, Operskalski B, Wang PS. Suicide risk during antidepressant treatment. Am J Psychiatry. Jan 2006;163(1):41-7. [Medline]. [Full Text].
[Best Evidence] Smith P, Yule W, Perrin S, et al. Cognitive-behavioral therapy for PTSD in children and adolescents: a preliminary randomized controlled trial. J Am Acad Child Adolesc Psychiatry. Aug 2007;46(8):1051-61. [Medline].
Stallard P, Smith E. Appraisals and cognitive coping styles associated with chronic post-traumatic symptoms in child road traffic accident survivors. J Child Psychol Psychiatry. Feb 2007;48(2):194-201. [Medline].
Taylor TL, Chemtob CM. Efficacy of treatment for child and adolescent traumatic stress. Arch Pediatr Adolesc Med. Aug 2004;158(8):786-91. [Medline].
Vitiello B. Prevention and treatment of the psychological consequences of trauma in children and adolescents. Epidemiol Psichiatr Soc. Jan-Mar 2004;13(1):10-3. [Medline].

