eMedicine Specialties > Pediatrics: Surgery > General Surgery

Atresia, Stenosis, and Other Obstruction of the Colon: Workup

Author: Nelson G Rosen, MD, FACS, FAAP, Assistant Professor of Surgery and Pediatrics, Albert Einstein College of Medicine; Attending Pediatric Surgeon and Director, Pediatric Trauma Center, Department of Pediatric General Surgery, Schneider Children's Hospital
Coauthor(s): Jeffrey Zitsman, MD, Director, Minimal Access Surgery, Associate Clinical Professor, Department of Surgery, Division of Pediatric Surgery, Children's Hospital of New York, New York Presbyterian Medical Center; Jeremy T Aidlen, MD, Fellow in Pediatric Surgery, North Shore-Long Island Jewish Health System, Schneider's Children's Hospital
Contributor Information and Disclosures

Updated: Apr 28, 2008

Workup

Laboratory Studies

In all children with neonatal bowel obstruction should, obtain electrolyte measurement and CBC count and perform a crossmatch prior to operative intervention.

Imaging Studies

  • Antenatal ultrasonography may reveal bowel loop distention or polyhydramnios.
  • Plain radiography of the abdomen reveals bowel obstruction and may reveal a prominent dilated loop. A prone view shows absence of gas in the rectum, although gas may be present if the film was obtained after the rectum was examined.
  • Contrast enema may be performed prior to surgery at the discretion of the surgeon and can be useful in ruling out the presence of other lesions downstream from the atresia. It reveals a microcolon with a rounded proximal end (see Media file 2).
  • Radiography in congenital colonic stenosis also reveals an obstructive pattern that may mimic atresia. Contrast enema reveals narrowing of the colon, with limited filling of the dilated proximal colon (see Media file 3).

Diagnostic Procedures

  • Rectal biopsy (performed either as a suction biopsy prior to surgical correction or at the time of operative correction) should be considered important in evaluating for associated Hirschsprung disease.42,29

More on Atresia, Stenosis, and Other Obstruction of the Colon

Overview: Atresia, Stenosis, and Other Obstruction of the Colon
Workup: Atresia, Stenosis, and Other Obstruction of the Colon
Treatment: Atresia, Stenosis, and Other Obstruction of the Colon
Follow-up: Atresia, Stenosis, and Other Obstruction of the Colon
Multimedia: Atresia, Stenosis, and Other Obstruction of the Colon
References

References

  1. Oldham KT. Atresia, stenosis and other obstructions of the colon. In: O' Neill JA, Jr, Rowe MI, Grosfeld JL, Fonkalsrud EW, Coran AG, eds. Pediatric Surgery. St. Louis, Mo: Mosby; 1998:1361-68.

  2. Gaub OC. Congenital stenosis and atresia of the intestinal tract above the rectum; with a report of an operated case of atresia of the sigmoid in an infant. Tr Am S A. 1922;40:582.

  3. Potts WJ. Congenital atresia of the intestine and colon. Surg Gynecol Obstet. 1947;85:14.

  4. Evans CH. Collective review: atresias of the gastrointestinal tract. Surg Gynecol Obstet. 1955;92:1-8.

  5. Davenport M, Bianchi A, Doig CM, Gough DC. Colonic atresia: current results of treatment. J R Coll Surg Edinb. Feb 1990;35(1):25-8. [Medline].

  6. Webb CH, Wangensteen OH. Am J Dis Child. 1931;4:232.

  7. Benson CD, Lotfi MW, Brogh AJ. Congenital atresia and stenosis of the colon. J Pediatr Surg. Apr 1968;3(2):253-7. [Medline].

  8. Powell RW, Raffensperger JG. Congenital colonic atresia. J Pediatr Surg. Apr 1982;17(2):166-70. [Medline].

  9. Freeman NV. Congenital atresia and stenosis of the colon. Br J Surg. 1966;53:595-7.

  10. Gross RE. The surgery of infancy and childhood. Philadelphia, Pa: WB Saunders & Co; 1953:150-74.

  11. Dalla Vecchia LK, Grosfeld JL, West KW, et al. Intestinal atresia and stenosis: a 25-year experience with 277 cases. Arch Surg. May 1998;133(5):490-6; discussion 496-7. [Medline].

  12. Kim S, Yedlin S, Idowu O. Colonic atresia in monozygotic twins. Am J Med Genet. Mar 20 2000;91(3):204-6. [Medline].

  13. Janik JS, Ein SH, Mancer K. Intestinal stricture after necrotizing enterocolitis. J Pediatr Surg. Aug 1981;16(4):438-43. [Medline].

  14. Kosloske AM, Burstein J, Bartow SA. Intestinal obstruction due to colonic stricture following neonatal necrotizing enterocolitis. Ann Surg. Aug 1980;192(2):202-7. [Medline].

  15. Virjee JP, Gill GJ, Desa D, et al. Strictures and other late complications of neonatal necrotising enterocolitis. Clin Radiol. Jan 1979;30(1):25-31. [Medline].

  16. Millar AJW, Rode H, Cywes S. Intestinal atresia and stenosis: colonic atresia. In: Ashcraft KW, ed. Pediatric Surgery. 3rd ed. Philadelphia, Pa: WB Saunders Company; 2000.

  17. Landes A, Shuckett B, Skarsgard E. Non-fixation of the colon in colonic atresia: a new finding. Pediatr Radiol. 1994;24(3):167-9. [Medline].

  18. Nitta K, Iwafuchi M, Ohsawa Y, et al. A case of congenital colonic atresia associated with atresia ani. J Pediatr Surg. Nov 1987;22(11):1025-6. [Medline].

  19. Asabe K, Nagasaki A. Double atresia of hindgut with ileal stenosis: a case report. Asian J Surg. Jan 2004;27(1):49-51. [Medline].

  20. Digray NC, Mengi Y, Goswamy HL, Thappa DR. Colorectal perforations in neonates with anorectal malformations. Pediatr Surg Int. 2001;17(1):42-4. [Medline].

  21. Pohlson EC, Hatch EI Jr, Glick PL, Tapper D. Individualized management of colonic atresia. Am J Surg. May 1988;155(5):690-2. [Medline].

  22. Akgur FM, Tanyel FC, Buyukpamukcu N, Hicsonmez A. Colonic atresia and Hirschsprung's disease association shows further evidence for migration of enteric neurons. J Pediatr Surg. Apr 1993;28(4):635-6. [Medline].

  23. Kim PC, Superina RA, Ein S. Colonic atresia combined with Hirschsprung's disease: a diagnostic and therapeutic challenge. J Pediatr Surg. Aug 1995;30(8):1216-7. [Medline].

  24. Siu KL, Kwok WK, Lee WY, Lee WH. A male newborn with colonic atresia and total colonic aganglionosis. Pediatr Surg Int. 1999;15(2):141-2. [Medline].

  25. Williams MD, Burrington JD. Hirschsprung's disease complicating colon atresia. J Pediatr Surg. Apr 1993;28(4):637-9. [Medline].

  26. Wang KS, Cahill JL, Skarsgard ED. Omphalocele, colonic atresia, and Hirschsprung's disease: an unusual cluster of malformations in a single patient. Pediatr Surg Int. Mar 2001;17(2-3):218-20. [Medline].

  27. Croaker GD, Harvey JG, Cass DT. Hirschsprung's disease, colonic atresia, and absent hand: a new triad. J Pediatr Surg. Sep 1997;32(9):1368-70. [Medline].

  28. Akgur FM, Olguner M, Hakguder G, Ozer E, Aktug T. Colonic atresia associated with Hirschsprung's disease: it is not a diagnostic challenge. Eur J Pediatr Surg. Dec 1998;8(6):378-9. [Medline].

  29. Draus JM Jr, Maxfield CM, Bond SJ. Hirschsprung's disease in an infant with colonic atresia and normal fixation of the distal colon. J Pediatr Surg. Feb 2007;42(2):e5-8. [Medline].

  30. Applegate KE, Sargent SK. Spontaneous colonic ischemia in a patient with Riley-Day syndrome. Pediatr Radiol. 1995;25(4):312-3. [Medline].

  31. Patten BM. Human Embryology. New York, NY: McGraw-Hill; 1953.

  32. Louw JH, Barnard CN. Congenital intestinal atresia. Lancet. 1955;ii:1065-7.

  33. Fairbanks TJ, Kanard RC, Del Moral PM, et al. Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway. J Pediatr Surg. Feb 2005;40(2):390-6. [Medline].

  34. Hollinshead WH. Anatomy for Surgeons. Vol 2. New York, NY: Hoeber-Harper; 1956.

  35. Gornall P. Management of intestinal atresia complicating gastroschisis. J Pediatr Surg. Jun 1989;24(6):522-4. [Medline].

  36. Wang NL, Yeh ML, Chang PY, et al. Prenatal and neonatal intussusception. Pediatr Surg Int. Apr 1998;13(4):232-6. [Medline].

  37. Al-Wafi A, Morris-Stiff G, Lari A. Colonic atresia secondary to a choledochal cyst. Pediatr Surg Int. Jul 1998;13(5-6):422-3. [Medline].

  38. Louw JH. Investigations into the etiology of congenital atresia of the colon. Dis Colon Rectum. 1964;7:471-478.

  39. Werler MM, Sheehan JE, Mitchell AA. Association of vasoconstrictive exposures with risks of gastroschisis and small intestinal atresia. Epidemiology. May 2003;14(3):349-54. [Medline].

  40. de Jesus LE, Marques AM, Rocha MS, et al. Left colon stenosis caused by tuberculosis. J Pediatr Surg. Oct 2004;39(10):e5-7. [Medline].

  41. Bland-Sutton JD. Imperforate ileum. Am J Med Sci. 1889;98:457-62.

  42. Cox SG, Numanoglu A, Millar AJ, Rode H. Colonic atresia: spectrum of presentation and pitfalls in management. A review of 14 cases. Pediatr Surg Int. Oct 2005;21(10):813-8. [Medline].

  43. Fishman SJ, Islam S, Buonomo C, Nurko S. Nonfixation of an atretic colon predicts Hirschsprung's disease. J Pediatr Surg. Jan 2001;36(1):202-4. [Medline].

  44. Ameh EA, Nmadu PT. Intestinal atresia and stenosis: a retrospective analysis of presentation, morbidity and mortality in Zaria, Nigeria. West Afr J Med. 2000;19:39-42. [Medline].

  45. Abu-Judeh HH, Methratta S, Ybasco A, et al. Congenital colonic stenosis. South Med J. Mar 2001;94(3):344-6. [Medline].

  46. Sturim HS, Ternberg JL. Congenital atresia of the colon. Surgery. Mar 1966;59(3):458-64. [Medline].

  47. Coran AG, Eraklis AJ. Atresia of the colon. Surgery. May 1969;65(5):828-31. [Medline].

  48. Smith GH, Glasson M. Intestinal atresia: factors affecting survival. Aust N Z J Surg. Feb 1989;59(2):151-6. [Medline].

  49. Barrack SM, Kyambi JM, Ndungu J, et al. Intestinal atresia and stenosis as seen and treated at Kenyatta National Hospital, Nairobi. East Afr Med J. Sep 1993;70(9):558-64. [Medline].

Further Reading

Keywords

colonic atresia, colonic stenosis, colonic stricture, colonic obstruction, congenital colon obstruction, colonic narrowing, abdominal distention, failure to pass meconium, narrowed colon, Hirschsprung disease, small left colon syndrome, obturation obstruction, meconium ileus, meconium plug, abdominal distention, failure to pass meconium, congenital stenosis, acquired stenosis, stricture, necrotizing enterocolitis, intestinal blockage, bowel obstruction, feeding intolerance
 
failure to thrive, colon atresia, small intestinal atresia, dilated bowel loops, polyhydramnios, abdominal wall defects, genitourinary tract abnormalities, anal atresia, imperforate anus, colonic perforation, omphalocele, aganglionosis, mesenteric vascular incident, cryptophthalmia syndrome, cleft lip and palate, dysplastic kidneys, proximal jejunal atresia, arthrogryposis, proximal intestinal atresia, neoplasm, malrotation, Riley-Day syndrome, spontaneous colon ischemia, coloboma, cataracts, facial hemihypertrophy

facial asymmetry, exophthalmia, bilateral optic nerve hypoplasia, vascular interruption, thrombosis, volvulus, herniation, bowel necrosis, duodenal atresia, bowel ischemic injury, internal hernia, choledochal cyst, volvulus, bowel infarction, Crohn disease, tuberculosis

Contributor Information and Disclosures

Author

Nelson G Rosen, MD, FACS, FAAP, Assistant Professor of Surgery and Pediatrics, Albert Einstein College of Medicine; Attending Pediatric Surgeon and Director, Pediatric Trauma Center, Department of Pediatric General Surgery, Schneider Children's Hospital
Nelson G Rosen, MD, FACS, FAAP is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, American Pediatric Surgical Association, American Trauma Society, Association of Military Surgeons of the US, Canadian Association of Pediatric Surgeons, and Eastern Association for the Surgery of Trauma
Disclosure: Nothing to disclose.

Coauthor(s)

Jeffrey Zitsman, MD, Director, Minimal Access Surgery, Associate Clinical Professor, Department of Surgery, Division of Pediatric Surgery, Children's Hospital of New York, New York Presbyterian Medical Center
Jeffrey Zitsman, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, American Pediatric Surgical Association, and International Pediatric Endosurgery Group
Disclosure: Nothing to disclose.

Jeremy T Aidlen, MD, Fellow in Pediatric Surgery, North Shore-Long Island Jewish Health System, Schneider's Children's Hospital
Jeremy T Aidlen, MD is a member of the following medical societies: American College of Surgeons
Disclosure: Nothing to disclose.

Medical Editor

Kurt D Newman, MD, Vice Chairman, Department of Pediatric Surgery, Children's National Medical Center; Professor, Departments of Surgery and Pediatrics, George Washington University School of Medicine
Kurt D Newman, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, American Pediatric Surgical Association, and Society of Surgical Oncology
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine.com, Inc
Disclosure: Pfizer Inc Stock Investment from broker recommendation; Avanir Pharma Stock Investment from broker recommendation

Managing Editor

Deborah F Billmire, MD, Associate Professor, Department of Surgery, Indiana University Medical Center
Deborah F Billmire, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, American College of Surgeons, American Pediatric Surgical Association, Phi Beta Kappa, and Society of Critical Care Medicine
Disclosure: Nothing to disclose.

CME Editor

H Biemann Othersen Jr, MD, Professor of Surgery and Pediatrics, Emeritus Head, Division of Pediatric Surgery, Medical University of South Carolina
H Biemann Othersen Jr, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, American Association for the Surgery of Trauma, American Burn Association, American Cancer Society, American College of Surgeons, American Medical Association, American Pediatric Surgical Association, American Society for Parenteral and Enteral Nutrition, American Surgical Association, American Thoracic Society, British Association of Paediatric Surgeons, Society for Surgery of the Alimentary Tract, Society of Critical Care Medicine, South Carolina Medical Association, Southeastern Surgical Congress, Southern Medical Association, Southern Society for Pediatric Research, and Southern Thoracic Surgical Association
Disclosure: Nothing to disclose.

Chief Editor

Marleta Reynolds, MD, Professor of Surgery, Feinberg School of Medicine, Northwestern University; Interim Head, Division of Pediatric Surgery, Department of Surgery, Children's Memorial Hospital of Chicago
Marleta Reynolds, MD is a member of the following medical societies: American Pediatric Surgical Association
Disclosure: Nothing to disclose.

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.