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Pediatric Hypertrophic Pyloric Stenosis Surgery Treatment & Management

  • Author: Michael S Irish, MD; Chief Editor: Eugene S Kim, MD, FACS, FAAP  more...
 
Updated: Mar 25, 2016
 

Approach Considerations

Although medical treatment (see Medical Therapy) has been used to manage pyloric stenosis, pyloromyotomy has been firmly established as the treatment of choice for this condition. Adequate preoperative resuscitation is essential. Fluid resuscitation is guided by adequate urine output (1 mL/kg/hr) and by normalization of acid-base disturbances and electrolyte and bicarbonate levels.

Outcome studies comparing open versus laparoscopic approaches to pyloromyotomy are becoming more numerous overall as the trend toward more minimally invasive procedures is becoming more important to the public. In one survey, cosmetic outcome was valued such that up to 88% of parents were willing to pay additional expenses for their children to have smaller scars.[26]

With a higher public demand for minimally invasive surgery, it is important to note the changing trends in surgical resident training. Cosper et al reported that 93% of surgeons agreed that residents need to perform at least four open pyloromyotomies in order to become competent in the procedure; however, 44% reported that their residents performed fewer than four, a finding explained partly by the increased use of a laparoscopic approach and partly by a decreased opportunity for residents in the operating room to acquire the necessary skills.[27]

The rate of complications associated with laparoscopic pyloromyotomy when a general surgery resident participates in the procedure is 5.4-fold higher than that associated with performance by a pediatric resident, despite close attending supervision.[28] However, because more surgical residents are specializing, as well as because there may be fewer general surgeons who are comfortable performing pyloromyotomies, patients with pyloric stenosis may eventually experience a healthcare access problem. The need for parents to travel longer distances to a larger center that offers this procedure (or performs a high volume of these procedures ) may result in further attempts at other modalities for treating pyloric stenosis.

For example, in an alternative approach used to address the pylorus externally, Zhang et al reported nine successful applications of endoscopic pyloromyotomy in resolving infantile hypertrophic pyloric stenosis.[29] After transabdominal ultrasonography was used to assess the wall thickness, a 5.9-mm gastroscope was used to create a 2- to 3-mm incision (if the wall was 4-6 mm thick) or 3- to 4-mm incision (if the wall was >6 mm thick). There were no complications of hemorrhage or perforation; however, one patient developed vomiting after 1 month. A repeat procedure resolved her symptoms. With further research, this may prove to be a safer, more effective, and simpler alternative to the current standard of care.

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Medical Therapy

The primacy of pyloromyotomy in the management of pyloric stenosis notwithstanding, medical management of this condition remains important. Early assessment and treatment of fluid, electrolyte, and acid-base disturbances are paramount. Urgent resuscitation, rather than emergency surgical intervention, is the rule. Once the diagnosis is made, fluid resuscitation is begun. Clinical and biochemical assessments are made and repeated to guide appropriate fluid repletion.

Nonsurgical management was described originally in Europe using a low-curd feeding of dextrose or breast milk; however, this treatment reportedly took months to complete and was associated with significant morbidity. Reports from Sweden showed that using intravenous (IV) nutrition alone also usually failed. Additionally, a biochemical approach of giving atropine or scopolamine was used to compensate for the lack of nitric oxide (NO) synthase (NOS) in the pylorus, which is thought to cause the hypertrophy. These anticholinergics were thought to decrease pyloric contractions; however, early success was lacking and for some time was thought to be only of historical interest.

In 1996, Nagita et al, in a Japanese study, reported successfully treating 21 of 23 infants (91%) with pyloric stenosis using IV atropine, administered at a dosage of 0.04-0.11 mg/kg/day until vomiting ceased, followed by oral atropine for 2 weeks.[30]

A subsequent Japanese study, by Kawahara et al in 2005, reported a success rate of 87% in 52 patients treated with IV and oral atropine.[31] Manometric studies were used to find the level of atropine that decreased tonic and phasic contractions in the pylorus. The dosing regimen of atropine was 0.01 mg/kg IV six times a day before feedings (median time, 1 week), followed by 0.02 mg/kg orally after vomiting stopped and infants could tolerate formula in the amount of 150 mL/kg (median time, 44 days).

Hospital stays in this study ranged from 6 to 36 days (median, 13 day); however, despite the longer hospital stay, the costs for the medical group were similar to those for the surgical group, without the inherent risks of general anesthesia and surgery. Regarding general outcomes, the two groups showed no difference in weight at age 1 year. Applying medical treatment for pyloric stenosis could prove useful to patients without sufficient access to surgical care or when surgery would be too risky.[31]

The authors of the study concluded that this medical treatment of pyloric stenosis is an effective alternative to pyloromyotomy if the length of hospitalization and the necessity of continuing oral atropine are accepted. Long-term studies have yet to be conducted to address recurrence rates, hospital costs in other countries, and caregiver compliance for atropine-treated patients with pyloric stenosis. In the United States, the Ramstedt pyloromyotomy remains the optimal treatment for pyloric stenosis.

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Surgical Therapy

Preparation for surgery

As noted (see Medical Therapy), pyloric stenosis is not a surgical emergency. The preoperative medical management of patients with pyloric stenosis is paramount for safe general anesthesia. Once the diagnosis is made, fluid resuscitation is begun to treat dehydration and electrolyte and acid-base disturbances. Clinical and biochemical assessments are made and repeated to guide appropriate fluid repletion.

Intravenous therapy consists of 5% dextrose in one-half isotonic sodium chloride solution (0.45% NaCl/D5W) at 1.5 times the maintenance rate. Although children with severe dehydration should receive deficit fluid therapy with isotonic sodium chloride solution (20 mL/kg) initially, ongoing resuscitation should be performed with 0.45% NaCl/D5W to prevent rapid changes in volume and electrolyte levels, which can result in seizures. When urine output has been demonstrated, potassium chloride (10-20 mEq/L) can be added to the fluids.

As a general guideline, infants are deemed adequately resuscitated for the operating room once the following criteria are met:

  • Good urine output has been demonstrated
  • Serum Cl  >100 mEq/dL
  • Serum HCO 3 – <30 mEq/dL

In some patients with severe volume abnormalities (>20%) and electrolyte abnormalities (Cl < 80 mEq/dL; HCO3 >35 mEq/dL; Na+ <120 mEq/L), resuscitation may take 48-72 hours. With serum bicarbonate levels exceeding 30 mEq/dL, the potential exists for myocardial dysfunction and respiratory depression. Patients should therefore be monitored for signs of apnea; if such signs are present, they may need to be intubated and mechanically ventilated until surgery is performed.

An alternative preoperative stabilization approach has been proposed for severely alkalemic patients to decrease the preoperative hospital stay. In a report of 16 infants with a pH exceeding 7.60, four patients received standard resuscitation for 4 days and then cimetidine at 10 mg/kg, and 12 received IV cimetidine on admission until the pH dropped below 7.50.[32] In all 16, the pH reached the goal the same day cimetidine therapy was initiated, and all underwent pyloromyotomy that day. No complications associated with cimetidine were reported. This type of prompt preoperative resuscitation may help reduce length of hospital stay and overall costs in infants with severe metabolic alkalosis.[33]

Operative details

Once the diagnosis of pyloric stenosis has been confirmed, adequate ongoing preoperative fluid resuscitation must be maintained by establishing adequate urine output (1 mL/kg/hr) and correcting acid-base disorders and electrolyte abnormalities. Regarding anesthetic induction for infants with pyloric stenosis, tracheal intubation with muscle paralysis seems to be superior to awake intubation, in that the former reduces the risk of desaturation and bradycardia due to multiple attempts at intubation.

Pyloromyotomy may be performed either as an open procedure, via a right-upper-quadrant horizontal incision or an umbilical incision (Tan-Bianchi operation), or as a laparoscopic procedure (see the images below).

Open pyloromyotomy. Open pyloromyotomy.
Laparoscopic pyloromyotomy. Laparoscopic pyloromyotomy.

In 1986, a Tan-Bianchi approach was described in which a pyloromyotomy was performed through a supraumbilical incision that afforded superior cosmesis.[34] In 2004, Blumer et al compared the umbilical approach with the right-upper-quadrant approach in 237 patients and found that the umbilical approach took 3.1 minutes longer (28.5 vs 31.6 min); however, this difference was clinically irrelevant, in that there were no significant differences regarding length of hospital stay, mucosal perforations, or wound infections.[35] The umbilical approach also was considered to provide a superior cosmetic outcome.

In 2004, Alberti et al reported modifying the Tan-Bianchi approach with a right semicircular umbilical incision, thus keeping all the incisions in the same axis, allowing for delivery of a larger pylorus, and decreasing the amount of retractor strain on the wound.[36] This approach resulted in a lower rate of hematoma formation and lower wound infection rates (0%) than supraumbilical incisions (16%), despite the use of prophylactic antibiotics with the semicircular umbilical approach.

In this modified Tan-Bianchi operation, after the pyloric channel is delivered from the abdomen, a seromuscular incision is made along the anterior border of the hypertrophied pylorus from 1-2 mm proximal to the duodenum to the distal antrum just proximal to the pylorus.[36] Great care must be taken not to incise or perforate the underlying mucosa. An alternative superficial V-shaped extension can be made at the duodenal end of the myotomy to reduce the risk of duodenal mucosal injury.

Other variations of the open abdominal approach include a technique reported by Yokomori et al in 2006, who used a semicircumumbilical incision to create a 1.5-cm sliding window with an 8-cm subcutaneous space.[37] This space was then slid 3-4 cm toward the right upper quadrant. The abdomen was entered and the pyloromyotomy performed intracorporeally within the window. This type of incision can afford an uneventful postoperative course, along with a good cosmetic outcome.

One study compared an umbilical approach using a transverse muscle cutting incision and a vertical linea alba incision and found no difference in terms of postoperative morbidity.[38] In addition, a double-Y or Alalayet pyloromyotomy may be superior to the Ramstedt technique in decreasing postoperative vomiting and increasing weight gain in the first week following surgery.

Another consideration with pyloromyotomy may be the presence of foveolar cell hyperplasia (FCH),[39] a type of redundant mucosa, which may be evident ultrasonographically in 12% of infantile hypertrophic pyloric stenosis cases. In patients diagnosed with FCH, an extended pyloromyotomy may decrease postoperative vomiting and reduce the need for gastric foveolar fold excision due to persistent postoperative vomiting.

A laparoscopic pyloromyotomy follows the same principles as an open procedure. First described by Alain et al in 1991,[40] the laparoscopic approach has been demonstrated as a safe alternative to exteriorizing the pylorus and improving cosmetic results.

The authors' approach entails creating a 5-mm camera port at the umbilicus. A 3-mm atraumatic, locking, grasping instrument is inserted in the right upper quadrant through a transabdominal stab incision over the duodenum. The grasping instrument is used to stabilize the pyloric channel. A 3-mm incision is made in the midepigastrium/left upper quadrant, over the pyloric olive, through which a sheathed arthrotome is passed (without a trocar). Alternatively, a Bovie electrocautery with an extended tip can be used to create the pyloromyotomy. The pylorus is incised in the same fashion as with the open procedure. The hypertrophied muscle is then bluntly split with a laparoscopic Tanner pyloric spreader.

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Postoperative Care

Crystalloid resuscitation is continued postoperatively until the patient returns to full feeding. Data suggest that infants with pyloric stenosis have an increased incidence of postoperative apnea and bradycardia. These infants should be placed on an apnea and cardiac monitor for 24 hours following the operation.

A decrease in the number of hospital days after operation depends to a certain degree on how rapidly feeding is started and advanced. In a 2002 study, Michalsky et al reported that having a clinical pathway decreased surgeon variability by advancing the diet to oral feedings within 5 hours after operation.[41] Additionally, the length of hospital stay was significantly reduced (41.8±9.7 vs 57.8±11.7 hours), as were hospital costs ($4555±$464 vs $5400±$1017).

In a contrasting 2002 study, Puapong et al showed that feeding ad libitum after the patient is awake resulted in a significantly faster return to full-strength feeding than a controlled feeding regimen (29.1 vs 5.1 hours), along with a shorter hospital stay (38.8±16.6 vs 25.1±10.9 days) and a significant decrease in cost per patient ($3560 vs $2290).[42] Both studies found that early initiation of feeding leads to better recovery and to cost savings.

The author has found the following feeding regimen to be safe and adequate.

  1. Give the patient nothing by mouth (NPO) for 6 hours in the recovery room
  2. Then, on demand, give 15 mL of Pedialyte every 2-3 hours for two feedings
  3. If 15 mL is tolerated, advance to 30 mL of Pedialyte every 2-3 hours for two feedings
  4. If 30 mL is tolerated, advance to 30 mL of full-strength formula every 2-3 hours for two feedings
  5. If full-strength formula is tolerated, advance to spontaneous feedings
  6. If vomiting occurs, repeat the step at which vomiting occurs and advance when tolerated
  7. If the patient is being breastfed and the mother has bottled milk, follow the above schedule

If the patient is being breastfed and no bottled milk is available, follow the schedule below:

  • Follow steps 1, 2, and 3 above
  • Have the patient breastfeed on each side for 5 minutes every 2 hours for two feedings
  • Have the patient breastfeed on each side for 10 minutes every 2 hours for two feedings
  • Have the patient breastfeed spontaneously

Slow feeding and gentle burping help prevent wet burps postoperatively. Intermittent vomiting persisting through the first postoperative week is sometimes observed in patients with a protracted course of emesis and severe dehydration preoperatively. Vomiting lasting longer than 7 days postoperatively should alert the physician to the possibility of an incomplete pyloromyotomy. An upper gastrointestinal (UGI) study may be obtained but is useful only for demonstrating gastroesophageal reflux; the radiographic appearances of pyloric stenosis may persist for several months following complete pyloromyotomy.

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Complications

Although pyloromyotomy is safe and curative and can be performed virtually without operative mortality (<0.5%) and morbidity (<10%), it is not without potential complications. Potential intraoperative and postoperative complications include bleeding, perforation, and wound infection.

Duodenal or gastric perforation, the most serious complication, rarely occurs; however, if it goes unrecognized before wound closure, devastating or lethal consequences are possible. The infant with an enteric leak develops pain, distention, fever, and peritonitis. Ongoing fluid requirements, generalized sepsis, vascular collapse, and death follow if the enteric leak is not recognized and treated. Suspected perforation postoperatively requires immediate reexploration. Recognition of this complication at the time of surgery is important.

Mucosal perforation most commonly results from extending the myotomy beyond the pyloric-duodenal junction. If perforation occurs, the mucosal defect should be repaired and the myotomy completed. An omental patch may be sutured to the perforation site, and a paraduodenal drain may be considered. If any question exists about the success of the closure, a UGI study can be obtained before feedings are initiated. The patient should continue to receive antibiotics until feedings are resumed.

Bleeding is a rare complication of pyloromyotomy. Other complications that are more common but less serious include superficial wound infections (usually Staphylococcus aureus) and postoperative vomiting. Patients with wound erythema, drainage, or both undergo wound opening and debridement and antibiotic therapy. Incomplete myotomy results in ongoing gastric outlet obstruction and requires reoperation. However, ongoing emesis after pyloromyotomy does not mean an incomplete myotomy was performed. Patients with prolonged preoperative obstruction develop gastric distention and dysmotility, which may cause postoperative emesis for up to 1 week after an adequate pyloromyotomy.

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Long-Term Monitoring

The follow-up care regimen involves a routine postoperative visit at 1 week to check wounds and to ensure that the patient is once again gaining weight.

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Contributor Information and Disclosures
Author

Michael S Irish, MD Adjunct Clinical Assistant Professor, Department of Surgery, University of Iowa, Roy J and Lucille A Carver College of Medicine; Consulting Pediatric Surgeon, Department of Pediatric Surgery, Blank Children's Hospital and Children's Hospital Physicians Group

Michael S Irish, MD is a member of the following medical societies: Sigma Xi, International Pediatric Endosurgery Group

Disclosure: Nothing to disclose.

Coauthor(s)

Philip M Bovet, MPH, DO, FACOFP Consulting Physician, Aspirus Clinics, Inc

Philip M Bovet, MPH, DO, FACOFP is a member of the following medical societies: American Academy of Family Physicians, American Medical Association, American Osteopathic Association, Wisconsin Medical Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Gail E Besner, MD Chief, Department of Pediatric Surgery, Principal Investigator, Center for Perinatal Research, Director, Pediatric Surgery Training Program, Associate Burn Director, Nationwide Children’s Hospital; H William Clatworthy, Jr, Professor of Surgery, Department of Surgery, Ohio State University College of Medicine

Gail E Besner, MD is a member of the following medical societies: American Surgical Association, Alpha Omega Alpha, American Academy of Pediatrics, American Burn Association, American College of Surgeons, American Gastroenterological Association, American Medical Association, American Medical Womens Association, American Pediatric Surgical Association, Association for Academic Surgery, Federation of American Societies for Experimental Biology, Society of Critical Care Medicine, Society of Surgical Oncology, Society of University Surgeons

Disclosure: Nothing to disclose.

Chief Editor

Eugene S Kim, MD, FACS, FAAP Associate Professor of Surgery, Division of Pediatric Surgery, Keck School of Medicine of the University of Southern California; Attending Pediatric Surgeon, Children's Hospital Los Angeles

Eugene S Kim, MD, FACS, FAAP is a member of the following medical societies: American Academy of Pediatrics, American Association for Cancer Research, American College of Surgeons, American Medical Association, American Pediatric Surgical Association, Association for Academic Surgery, Society of Laparoendoscopic Surgeons, Society of University Surgeons, Texas Medical Association, Children's Oncology Group

Disclosure: Nothing to disclose.

Additional Contributors

Aviva L Katz, MD Assistant Professor of Surgery, University of Pittsburgh School of Medicine; Consulting Staff, Division of General and Thoracic Surgery, Children's Hospital of Pittsburgh

Aviva L Katz, MD is a member of the following medical societies: American Academy of Pediatrics, Association of Women Surgeons, American College of Surgeons, American Pediatric Surgical Association, Physicians for Social Responsibility, Wilderness Medical Society

Disclosure: Nothing to disclose.

References
  1. Cooper WO, Griffin MR, Arbogast P. Very early exposure to erythromycin and infantile hypertrophic pyloric stenosis. Arch Pediatr Adolesc Med. 2002 Jul. 156(7):647-50. [Medline].

  2. Huang PL, Dawson TM, Bredt DS, et al. Targeted disruption of the neuronal nitric oxide synthase gene. Cell. 1993 Dec 31. 75(7):1273-86. [Medline].

  3. Huang LT, Tiao MM, Lee SY, Hsieh CS, Lin JW. Low plasma nitrite in infantile hypertrophic pyloric stenosis patients. Dig Dis Sci. 2006 May. 51(5):869-72. [Medline].

  4. Everett KV, Chioza BA, Georgoula C, Reece A, Capon F, Parker KA, et al. Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11q14-q22 and Xq23. Am J Hum Genet. 2008 Mar. 82(3):756-62. [Medline].

  5. Jackson L, Kline AD, Barr MA. de Lange syndrome: a clinical review of 310 individuals. Am J Med Genet. 1993 Nov 15. 47(7):940-6. [Medline].

  6. Battaglia A, Chines C, Carey JC. The FG syndrome: report of a large Italian series. Am J Med Genet A. 2006 Oct 1. 140(19):2075-9. [Medline].

  7. Liede A, Pal T, Mitchell M. Delineation of a new syndrome: clustering of pyloric stenosis, endometriosis, and breast cancer in two families. J Med Genet. 2000 Oct. 37(10):794-6. [Medline]. [Full Text].

  8. Tiao MM, Tsai SS, Kuo HW, Yang CY. Epidemiological features of infantile hypertrophic pyloric stenosis in Taiwan: a national study 1996-2004. J Gastroenterol Hepatol. 2011 Jan. 26(1):78-81. [Medline].

  9. To T, Wajja A, Wales PW. Population demographic indicators associated with incidence of pyloric stenosis. Arch Pediatr Adolesc Med. 2005 Jun. 159(6):520-5. [Medline].

  10. Carter CO, Evans KA. Inheritance of congenital pyloric stenosis. J Med Genet. 1969 Sep. 6(3):233-54. [Medline].

  11. Pedersen RN, Garne E, Loane M, Korsholm L, Husby S. Infantile hypertrophic pyloric stenosis: a comparative study of incidence and other epidemiological characteristics in seven European regions. J Matern Fetal Neonatal Med. 2008 Sep. 21(9):599-604. [Medline].

  12. Yoshizawa J, Eto T, Higashimoto Y. Ultrasonographic features of normalization of the pylorus after pyloromyotomy for hypertrophic pyloric stenosis. J Pediatr Surg. 2001 Apr. 36(4):582-6. [Medline].

  13. Pranikoff T, Campbell BT, Travis J. Differences in outcome with subspecialty care: pyloromyotomy in North Carolina. J Pediatr Surg. 2002 Mar. 37(3):352-6. [Medline].

  14. Safford SD, Pietrobon R, Safford KM. A study of 11,003 patients with hypertrophic pyloric stenosis and the association between surgeon and hospital volume and outcomes. J Pediatr Surg. 2005 Jun. 40(6):967-72; discussion 972-3. [Medline].

  15. Hendrickson RJ, Yu S, Bruny JL, Partrick DA, Petty JK, Bensard DD. Early experience with laparoscopic pyloromyotomy in a teaching institution. JSLS. 2005 Oct-Dec. 9(4):386-8. [Medline].

  16. Yagmurlu A, Barnhart DC, Vernon A. Comparison of the incidence of complications in open and laparoscopic pyloromyotomy: a concurrent single institution series. J Pediatr Surg. 2004 Mar. 39(3):292-6; discussion 292-6. [Medline].

  17. Campbell BT, McLean K, Barnhart DC. A comparison of laparoscopic and open pyloromyotomy at a teaching hospital. J Pediatr Surg. 2002 Jul. 37(7):1068-71; discussion 1068-71. [Medline].

  18. [Guideline] Guidelines for surgical treatment of infantile hypertrophic pyloric stenosis. International Pediatric Endosurgery Group. Available at http://www.ipeg.org/pyloric-stenosis/. November 5, 2002; Accessed: February 10, 2016.

  19. Oomen MW, Hoekstra LT, Bakx R, Ubbink DT, Heij HA. Open Versus Laparoscopic Pyloromyotomy for Hypertrophic Pyloric Stenosis: A Systematic Review and Meta-Analysis Focusing on Major Complications. Surg Endosc. 2012 Feb 21. [Medline].

  20. Teele RL, Smith EH. Ultrasound in the diagnosis of idiopathic hypertrophic pyloric stenosis. N Engl J Med. 1977 May 19. 296(20):1149-50. [Medline].

  21. Bensard DD, Hendrickson RJ, Clark KS, Giesting KJ, Kokoska ER. Use of ultrasound measurements to direct laparoscopic pyloromyotomy in infants. JSLS. 2010 Oct-Dec. 14(4):553-7. [Medline]. [Full Text].

  22. Leaphart CL, Borland K, Kane TD, Hackam DJ. Hypertrophic pyloric stenosis in newborns younger than 21 days: remodeling the path of surgical intervention. J Pediatr Surg. 2008 Jun. 43(6):998-1001. [Medline].

  23. Mullassery D, Mallappa S, Shariff R, Craigie RJ, Losty PD, Kenny SE, et al. Negative exploration for pyloric stenosis--is it preventable?. BMC Pediatr. 2008 Sep 24. 8:37. [Medline].

  24. Boneti C, McVay MR, Kokoska ER, Jackson RJ, Smith SD. Ultrasound as a diagnostic tool used by surgeons in pyloric stenosis. J Pediatr Surg. 2008 Jan. 43(1):87-91; discussion 91. [Medline].

  25. McVay MR, Copeland DR, McMahon LE, Cosper GH, McCallie TG, Kokoska ER, et al. Surgeon-performed ultrasound for diagnosis of pyloric stenosis is accurate, reproducible, and clinically valuable. J Pediatr Surg. 2009 Jan. 44(1):169-71; discussion 171-2. [Medline].

  26. Haricharan RN, Aprahamian CJ, Morgan TL, Harmon CM, Georgeson KE, Barnhart DC. Smaller scars--what is the big deal: a survey of the perceived value of laparoscopic pyloromyotomy. J Pediatr Surg. 2008 Jan. 43(1):92-6; discussion 96. [Medline].

  27. Cosper GH, Menon R, Hamann MS, Nakayama DK. Residency training in pyloromyotomy: a survey of 331 pediatric surgeons. J Pediatr Surg. 2008 Jan. 43(1):102-8. [Medline].

  28. Haricharan RN, Aprahamian CJ, Celik A, Harmon CM, Georgeson KE, Barnhart DC. Laparoscopic pyloromyotomy: effect of resident training on complications. J Pediatr Surg. 2008 Jan. 43(1):97-101. [Medline].

  29. Zhang YX, Nie YQ, Xiao X, Yu NF, Li QN, Deng L. [Treatment of congenital hypertrophic pyloric stenosis with endoscopic pyloromyotomy]. Zhonghua Er Ke Za Zhi. 2008 Apr. 46(4):247-51. [Medline].

  30. Nagita A, Yamaguchi J, Amemoto K. Management and ultrasonographic appearance of infantile hypertrophic pyloric stenosis with intravenous atropine sulfate. J Pediatr Gastroenterol Nutr. 1996 Aug. 23(2):172-7. [Medline].

  31. Kawahara H, Takama Y, Yoshida H. Medical treatment of infantile hypertrophic pyloric stenosis: should we always slice the "olive"?. J Pediatr Surg. 2005 Dec. 40(12):1848-51. [Medline].

  32. Tang KS, Huang IF, Shih HH, Huang YH, Wu CH, Lu CC, et al. Factors contributing to prolonged hospitalization of patients with infantile hypertrophic pyloric stenosis. Pediatr Neonatol. 2011 Aug. 52(4):203-7. [Medline].

  33. Banieghbal B. Rapid correction of metabolic alkalosis in hypertrophic pyloric stenosis with intravenous cimetidine: preliminary results. Pediatr Surg Int. 2009 Mar. 25(3):269-71. [Medline].

  34. Tan KC, Bianchi A. Circumumbilical incision for pyloromyotomy. Br J Surg. 1986 May. 73(5):399. [Medline].

  35. Blumer RM, Hessel NS, van Baren R. Comparison between umbilical and transverse right upper abdominal incision for pyloromyotomy. J Pediatr Surg. 2004 Jul. 39(7):1091-3. [Medline].

  36. Alberti M, Cheli M, Locatelli G. A new technical variant for extramucosal pyloromyotomy, The Tan-Bianchi operation moves to the right. J Ped Surg. 2004. 39:53-6. [Medline].

  37. Yokomori K, Oue T, Odajima T, Baba N, Hashimoto D. Pyloromyotomy through a sliding umbilical window. J Pediatr Surg. 2006 Dec. 41(12):2066-8. [Medline].

  38. Mullassery D, Shariff R, Craigie RJ, Losty PD, Kenny SE, Baillie CT. Umbilical pyloromyotomy: comparison of vertical linea alba and transverse muscle cutting incisions. J Pediatr Surg. 2007 Mar. 42(3):525-7. [Medline].

  39. Tan HL, Blythe A, Kirby CP, Gent R. Gastric Foveolar Cell Hyperplasia and its Role in Postoperative Vomiting in Patients with Infantile Hypertrophic Pyloric Stenosis. Eur J Pediatr Surg. 2009 Feb 25. [Medline].

  40. Alain JL, Grousseau D, Terrier G. Extramucosal pylorotomy by laparoscopy. J Pediatr Surg. 1991 Oct. 26(10):1191-2. [Medline].

  41. Michalsky MP, Pratt D, Caniano DA. Streamlining the care of patients with hypertrophic pyloric stenosis: application of a clinical pathway. J Pediatr Surg. 2002 Jul. 37(7):1072-5; discussion 1072-5. [Medline].

  42. Puapong D, Kahng D, Ko A. Ad libitum feeding: safely improving the cost-effectiveness of pyloromyotomy. J Pediatr Surg. 2002 Dec. 37(12):1667-8. [Medline].

 
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Diagram of the anatomic changes associated with pyloric stenosis.
Technique used for examining an infant with pyloric stenosis. The infant is best examined from the right, with mild pressure applied using the first 3 fingers of the right hand in a cephalad direction. Careful examination reveals an oblong, smooth, hard mass that is 1-2 cm in length. This mass is the hypertrophied pylorus and is commonly referred to as an olive.
Upper gastrointestinal study used for diagnosing pyloric stenosis.
Longitudinal ultrasonogram of pyloric stenosis. Pyloric stenosis is diagnosed by the demonstration of an elongated sausage-shaped mass with a pyloric diameter greater than 14 mm, a muscular thickness greater than 4 mm, and a length of more than 16 mm.
Open pyloromyotomy.
Laparoscopic pyloromyotomy.
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Table 1. Clinical Findings in Dehydrated Infants With Pyloric Stenosis
Level of Dehydration Mild Moderate Severe
Estimated Volume Deficit 5% (50 mL/kg) 10% (100 mL/kg) 15% (150 mL/kg)
       
Clinical Findings      
Skin (touch) Normal Dry, pale Clammy
Skin turgor Normal Tenting None
Mucus membranes Moist Dry Parched
Eyes Normal Deep-set Sunken
Tearing Present Reduced None
Fontanelle Normal (flat) Soft Sunken
CNS Normal Irritable Lethargic/obtunded
Heart rate Normal Slightly increased Increased
Pulse quality Normal Weak Feeble/impalpable
Capillary refill Normal ~2 sec >3 sec
Urine output Normal Decreased Anuric
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