Pediatric Surgery for Central Venous Access Workup
- Author: Floriano Putigna, DO, FAAEM; Chief Editor: Marleta Reynolds, MD more...
Laboratory Studies
Routine laboratory studies do not play a major role in determining the need for central access unless directed by the patient's history and physical findings.
However, a relative contraindication to placing a central line is an abnormality of the coagulation studies (ie, increased prothrombin time [PT], partial thromboplastin time [PTT], international normalized ratio [INR]). This also holds true for a platelet count less than 10,000. If central access is needed despite these laboratory finding abnormalities, then a femoral site is preferred secondary to its ability to easily compress.
Imaging Studies
Plain radiography should be performed after central venous catheter (CVC) insertion to ensure its proper placement and to rule out iatrogenic injuries such as a pneumothorax.
An interesting technique for CVC insertion used with increased frequency with promising results is ultrasonographic guidance. Several studies have demonstrated the ease with which nonradiologist practitioners can use ultrasonography to access central veins.[7] Although skilled clinicians can successfully achieve access using landmarks alone, the anatomy may be distorted in obese patients. In these cases, ultrasonographic guidance is especially helpful.
In several studies, ultrasonography-guided approaches in the femoral, internal jugular, or subclavian veins were faster, easier, and caused fewer complications than the landmark technique alone.[8, 9]
Ultrasonographic guidance is usually performed using a 7.5-MHz linear probe. Color Doppler can help differentiate the vein from the artery and can reduce the risk of an arterial puncture. By convention, the marker on the probe faces the patient's right or the patient's head, depending on the line being placed. The structures on the left side (as viewed) of the screen are always on the side of the marker. For example, in a right femoral line approach with the marker to the patient's right, the artery is on the left side of the screen, and the vein is to the right of the artery. Once again, by using color Doppler, the vessels can be easily distinguished.
In the authors' institution, we use small hand-held units, such as the SonoSite 180 & Titan (SonoSite Inc, Bothell, WA), which are readily available and have proven easy to use.
Forssmann W. Die Sondierung rechten Herzens. Klin Wschr. 1929;8:2080.
Aubaniac R. [Subclavian intravenous injection; advantages and technic]. Presse Med. Oct 25 1952;60(68):1456. [Medline].
Lomonte C, Basile C. [Management of central venous catheter: prevention of thrombosis and bacteremia.]. G Ital Nefrol. Jan-Feb 2009;26(1):73-80. [Medline].
Mogayzel PJ Jr, Pierce E, Mills J, et al. Accuracy of tobramycin levels obtained from central venous access devices in patients with cystic fibrosis is technique dependent. Pediatr Nurs. Nov-Dec 2008;34(6):464-8; quiz 468-9. [Medline].
Soucy P. Experiences with the use of the Port-a-Cath in children. J Pediatr Surg. Aug 1987;22(8):767-9. [Medline].
Knebel P, Lopez-Benitez R, Fischer L, et al. Insertion of Totally Implantable Venous Access Devices: An Expertise-Based, Randomized, Controlled Trial (NCT00600444). Ann Surg. Jun 2011;253(6):1111-7. [Medline].
Skippen P, Kissoon N. Ultrasound guidance for central vascular access in the pediatric emergency department. Pediatr Emerg Care. Mar 2007;23(3):203-7. [Medline].
[Best Evidence] Leung J, Duffy M, Finckh A. Real-time ultrasonographically-guided internal jugular vein catheterization in the emergency department increases success rates and reduces complications: a randomized, prospective study. Ann Emerg Med. Nov 2006;48(5):540-7. [Medline].
Verghese ST, McGill WA, Patel RI, et al. Ultrasound-guided internal jugular venous cannulation in infants: a prospective comparison with the traditional palpation method. Anesthesiology. Jul 1999;91(1):71-7. [Medline].
Casado-Flores J, Barja J, Martino R. Complications of central venous catheterization in critically ill children. Pediatric Critical Care Med. 2001;2(1):57-62. [Medline].
Goede MR, Coopersmith CM. Catheter-related bloodstream infection. Surg Clin North Am. Apr 2009;89(2):463-74. [Medline].
Henrickson KJ, Axtell RA, Hoover SM, et al. Prevention of central venous catheter-related infections and thrombotic events in immunocompromised children by the use of vancomycin/ciprofloxacin/heparin flush solution: A randomized, multicenter, double-blind trial. J Clin Oncol. Mar 2000;18(6):1269-78. [Medline].
Massicotte MP, Dix D, Monagle P, Adams M, Andrew M. Central venous catheter related thrombosis in children: analysis of the Canadian Registry of Venous Thromboembolic Complications. J Pediatr. Dec 1998;133(6):770-6. [Medline].
Chaitowitz, I; Heng, R; Bell, K. Managing peripherally inserted central catheter-related venous thrombosis: How I do it. Australasian Radiology. April 2006;50(2):132-135.
Jacobs BR, Haygood M, Hingl J. Recombinant tissue plasminogen activator in the treatment of central venous catheter occlusion in children. J Pediatr. Oct 2001;139(4):593-6. [Medline].
Skippen P, Kissoon N. Ultrasound guidance for central vascular access in the pediatric emergency department. Pediatr Emerg Care. Mar 2007;23(3):203-7. [Medline].
Cairo MS, Spooner S, Sowden L, et al. Long-term use of indwelling multipurpose silastic catheters in pediatric cancer patients treated with aggressive chemotherapy. J Clin Oncol. May 1986;4(5):784-8. [Medline].
Chiang VW, Baskin MN. Uses and complications of central venous catheters inserted in a pediatric emergency department. Pediatr Emerg Care. Aug 2000;16(4):230-2. [Medline].
Dolcourt JL, Bose CL. Percutaneous insertion of silastic central venous catheters in newborn infants. Pediatrics. Sep 1982;70(3):484-6. [Medline].
Frey AM. Pediatric peripherally inserted central catheter program report: a summary of 4,536 catheter days. J Intraven Nurs. Nov-Dec 1995;18(6):280-91. [Medline].
McGee DC, Gould MK. Preventing complications of central venous catheterization. N Engl J Med. Mar 20 2003;348(12):1123-33. [Medline].
Roberts JR, Hedges JR. Clinical Procedures in Emergency Medicine. 3rd ed. Philadelphia, PA: WB Saunders Co; 1998:295-301.
Stovroff M, Teague WG. Intravenous access in infants and children. Pediatr Clin North Am. Dec 1998;45(6):1373-93, viii. [Medline].
| Age (y) | Weight (kg) | Gauge | French | Length (cm) |
| < 1, newborn | 4-8 | 24 | 3.0 | 5-12 |
| < 1 | 5-10 | 22 | 3.0-3.5 | 5-12 |
| 1-3 | 10-15 | 20 | 4.0 | 5-15 |
| 3-8 | 15-30 | 18-20 | 4.0-5.0 | 5-25 |
| >8 | 30-70 | 16-20 | 5.0-8.0 | 5-30 |

