Klinefelter Syndrome Medication

Updated: Apr 20, 2017
  • Author: Germaine L Defendi, MD, MS, FAAP; Chief Editor: Luis O Rohena, MD, FAAP, FACMG  more...
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Medication

Medication Summary

Androgen replacement therapy is used to correct androgen deficiency, to provide appropriate virilization, and to improve psychosocial status. Regular testosterone injections can promote strength and facial hair growth; build a more muscular body type; increase sexual desire; enlarge the testes; improve mood, self-image, and behavior; and protect against precocious osteoporosis.

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Androgen

Class Summary

Exogenous androgen (testosterone) is the treatment of choice for many aspects of Klinefelter syndrome.

Testosterone enanthate (Delatestryl) or cypionate (Depo-Testosterone)

Major therapeutic aims are to reduce serum gonadotropin concentrations to the upper limits of normal and to gradually induce virilization.

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