Prader-Willi Syndrome Medication

Updated: Dec 24, 2015
  • Author: Ann Scheimann, MD, MBA; Chief Editor: Luis O Rohena, MD  more...
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Medication

Medication Summary

Currently, no medications have been found to effectively modify hyperphagia. Growth hormone therapy in patients with growth hormone deficiency improves lean body mass, corrects osteopenia, does not appear to enhance the development of scoliosis, and anecdotally modulates behavior in some patients. [28, 43, 44, 45] Supplementation of sex steroids does improve secondary sex characteristics but may aggravate behavioral disorders. [28]

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Growth hormone agents

Class Summary

These agents improve symptoms of growth hormone deficiency.

Human growth hormone (Saizen, Genotropin, Humatrope, Nutropin, Serostim)

Stimulates growth of linear bone, skeletal muscle, and organs. Stimulates erythropoietin, increasing RBC mass.

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