eMedicine Specialties > Pediatrics: General Medicine > Hematology
Leukocytosis: Differential Diagnoses & Workup
Updated: Nov 3, 2009
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
- Multimedia
Differential Diagnoses
Other Problems to Be Considered
Chronic granulocytic (myelogenous) leukemia
Workup
Laboratory Studies
- In interpreting leukocytosis on the CBC count, consider the following:
- Clinical features
- Duration
- Differential
- Remainder of the CBC count
- An isolated WBC count is often ordered to minimize cost. However, most of the time, the WBC count cannot be accurately interpreted without the rest of the CBC differential. Therefore, if any question of interpretation is noted, obtain the entire CBC count with differential.
More on Leukocytosis |
| Overview: Leukocytosis |
Differential Diagnoses & Workup: Leukocytosis |
| Treatment & Medication: Leukocytosis |
| Follow-up: Leukocytosis |
| Multimedia: Leukocytosis |
| References |
| « Previous Page | Next Page » |
References
Cotran RS, Kumar V, Collins T. Robbins Pathologic Basis of Disease. 6th ed. Philadelphia, PA: WB Saunders; 1999:644-96.
Lee GM, Harper MB. Risk of bacteremia for febrile young children in the post-Haemophilus influenzae type b era. Arch Pediatr Adolesc Med. Jul 1998;152(7):624-8. [Medline].
Brown L, Shaw T, Wittlake WA. Does leucocytosis identify bacterial infections in febrile neonates presenting to the emergency department?. Emerg Med J. Apr 2005;22(4):256-9. [Medline].
Hsiao AL, Chen L, Baker D. Incidence and predictors of serious bacterial infections among 57- to 180-day-old infants. Pediatrics. May 2006;117:1695-1701.
Hsiao R, Omar SA. Outcome of extremely low birth weight infants with leukemoid reaction. Pediatrics. Jul 2005;116(1):e43-51. [Medline].
Rosa JS, Schwindt CD, Oliver SR, Leu SY, Flores RL, Galassetti PR. Exercise leukocyte profiles in healthy, type 1 diabetic, overweight, and asthmatic children. Pediatr Exerc Sci. Feb 2009;21(1):19-33. [Medline].
Aydogan M, Aydogan A, Kara B, Basim B, Erdogan S. Transient peripheral leukocytosis in children with afebrile seizures. J Child Neurol. Jan 2007;22(1):77-9. [Medline].
Alioglu B, Ozyurek E, Avci Z, Atalay B, Caner H, Ozbek N. Peripheral blood picture following mild head trauma in children. Pediatr Int. Jun 2008;50(3):281-3. [Medline].
Furlan JC, Krassioukov AV, Fehlings MG. Hematologicl abnormalities within the first week after acute isolated traumatic cervical spinal cord injury: a case-control cohort study. Spine. Nov/2006;31:2674-83. [Medline].
Bonadio WA. Evaluation and management of serious bacterial infections in the febrile young infant. Pediatr Infect Dis J. Dec 1990;9(12):905-12. [Medline].
Dinauer MC. The phagocyte system and disorders of granulopoiesis and granulocyte function. In: Nathan and Oski's Hematology of Infancy and Childhood. Vol 1. 5th ed. Philadelphia, PA: WB Saunders; 1998:889.
Izbicki G, Rudensky B, Na'amad M, Hershko C, Huerta M, Hersch M. Transfusion-related leukocytosis in critically ill patients. Crit Care Med. Feb 2004;32(2):439-42. [Medline].
Lichtman MA, Rowe JM. Hyperleukocytic leukemias: rheological, clinical, and therapeutic considerations. Blood. Aug 1982;60(2):279-83. [Medline].
Shah SS, Shofer FS, Seidel JS, Baren JM. Significance of extreme leukocytosis in the evaluation of febrile children. Pediatr Infect Dis J. Jul 2005;24(7):627-30. [Medline].
Wang, CW, Lukens JN. Sickle cell anemia and other sickling syndromes. In: Wintrobe's Clinical Hematology. Vol 1. 10th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 1999:1346-97.
Wright IM, Skinner AM. Post-transfusion white cell count in the sick preterm neonate. J Paediatr Child Health. Feb 2001;37(1):44-6. [Medline].
Further Reading
Keywords
leukocytosis, white blood cell count, WBC count, increased WBCs, neutrophil count, neutrophilia, lymphocyte count, lymphocytosis, monocyte count, monocytosis, eosinophilic granulocyte count, eosinophilia, fever, abdominal pain
Differential Diagnoses & Workup: Leukocytosis