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Leukocytosis Differential Diagnoses

  • Author: Susumu Inoue, MD; Chief Editor: Robert J Arceci, MD, PhD  more...
 
Updated: Jul 10, 2015
 
 
 
Contributor Information and Disclosures
Author

Susumu Inoue, MD Professor of Pediatrics and Human Development, Michigan State University College of Human Medicine; Clinical Professor of Pediatrics, Wayne State University School of Medicine; Director of Pediatric Hematology/Oncology, Associate Director of Pediatric Education, Department of Pediatrics, Hurley Medical Center

Susumu Inoue, MD is a member of the following medical societies: American Academy of Pediatrics, American Society of Clinical Oncology, American Society of Hematology, American Society of Pediatric Hematology/Oncology, Society for Pediatric Research

Disclosure: Nothing to disclose.

Specialty Editor Board

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Gary D Crouch, MD Associate Professor, Program Director of Pediatric Hematology-Oncology Fellowship, Department of Pediatrics, Uniformed Services University of the Health Sciences

Gary D Crouch, MD is a member of the following medical societies: American Academy of Pediatrics, American Society of Hematology

Disclosure: Nothing to disclose.

Chief Editor

Robert J Arceci, MD, PhD Director, Children’s Center for Cancer and Blood Disorders, Department of Hematology/Oncology, Co-Director of the Ron Matricaria Institute of Molecular Medicine, Phoenix Children’s Hospital; Editor-in-Chief, Pediatric Blood and Cancer; Professor, Department of Child Health, University of Arizona College of Medicine

Robert J Arceci, MD, PhD is a member of the following medical societies: American Association for the Advancement of Science, American Association for Cancer Research, American Pediatric Society, American Society of Hematology, American Society of Pediatric Hematology/Oncology

Disclosure: Nothing to disclose.

Acknowledgements

Gary R Jones, MD Associate Medical Director, Clinical Development, Berlex Laboratories

Gary R Jones, MD is a member of the following medical societies: American Academy of Pediatrics, American Society of Pediatric Hematology/Oncology, and Western Society for Pediatric Research

Disclosure: Nothing to disclose.

References
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WBC counts.
Table. Normal Leukocyte Counts
  Total Leukocytes* Lymphocytes Neutrophils Monocytes Eosinophils
Age MeanRange MeanRange% MeanRange% Mean% Mean%
Birth ...... 4.22-7.3... 42-6... 0.6... 0.1...
12 h ...... 4.22-7.3... 117.8-14.5... 0.6... 0.1...
24 h ...... 4.22-7.3... 97-12... 0.6... 0.1...
1-4 wk ...... 5.62.9-9.1... 3.61.8-5.4... 0.7... 0.2...
6 mo 11.96-17.5 7.34-13.561 3.81-8.532 0.65 0.33
1 y 11.46-17.5 7.04-10.561 3.51.5-8.531 0.65 0.33
2 y 10.66-17 6.33-9.559 3.51.5-8.533 0.55 0.33
4 y 9.15.5-15.5 4.52-850 3.81.5-8.542 0.55 0.33
6 y 8.55-14.5 3.51.5-742 4.31.5-851 0.45 0.23
8 y 8.34.5-13.5 3.31.5-6.839 4.41.5-853 0.44 0.22
10 y 8.14.5-13.5 3.11.5-6.538 4.41.8-854 0.44 0.22
16 y 7.84.5-13 2.81.2-5.235 4.41.8-857 0.45 0.23
21 y 7.44.5-11 2.51-4.834 4.41.8-7.759 0.34 0.23
 



* Numbers of leukocytes are in X 109 \L or thousands per μ L; ranges are estimates of 95% confidence limits; and percentages refer to differential counts.



Neutrophils include band cells at all ages and a small number of metamyelocytes and myelocytes in the first few days of life.



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