Lumbosacral Spondylolysis Treatment & Management
- Author: Achilles Litao, MD; Chief Editor: Craig C Young, MD more...
Acute Phase
Rehabilitation Program
Physical Therapy
The approach to the treatment of lumbosacral spondylolysis (lumbar spondylolysis) is based on the stage of the bony lesion as guided by radiography and nuclear medicine or SPECT scanning investigations, as well as symptomatology.[11, 30] The complete healing of the bony lesion is the ultimate goal in treating patients with lumbosacral spondylolysis (lumbar spondylolysis).
Acute phase
Some patients present with a spondylolytic defect on plain radiography and also have positive findings on bone scanning. This can represent a recent-onset defect on the pars interarticularis[11] or a healing spondylolysis. Bracing and rest are the cornerstones of treatment for this type of lesion.[30] Pain control and avoiding sports are also part of the acute phase or rehabilitation.
Transcutaneous electrical nerve stimulation (TENS) has had widespread use as a therapeutic adjunct to the pharmacologic management of pain, but its effectiveness in chronic low back pain remains controversial. Khadilkar et al selected 4 randomized controlled clinical trials that met their selection criteria and that compared TENS to placebo for the management of chronic low back pain.[31] The investigators found conflicting evidence in 2 trials regarding whether TENS had any benefit in reducing back pain intensity, whereas 2 trials showed consistent evidence that TENS did not improve back-specific functional status.[31]
In addition, Khadilkar et al found conflicting results in 2 studies regarding generic health status: 1 study showed no improvement on the modified Sickness Impact Profile, whereas another study showed significant improvements on several, but not all subsections of the Short Form-36 (SF-36) Health Survey.[31] Moreover, multiple physical outcome measures lacked statistically significant improvement relative to placebo. The investigators concluded that at present, the evidence does not support the use of TENS in the routine management of chronic low back pain.[31]
Acupuncture has also had widespread use in the management of pain, with conflicting results. Yuan et al conducted a systematic review of randomized controlled trials to explore the evidence for the effectiveness of acupuncture for nonspecific low back pain.[32] Twenty-three trials with 6359 patients met the investigators' inclusion criteria and classified into 5 types of comparisons, 6 of which were of high quality.
Yuan et al found moderate evidence that acupuncture is more effective than no treatment, and strong evidence of no significant difference between acupuncture and sham acupuncture, for short-term pain relief.[32] In addition, the investigators found strong evidence that acupuncture can be a useful supplement to other forms of conventional therapy for nonspecific low back pain, but further investigation is needed. Yuan et al concluded that acupuncture versus no treatment, and as an adjunct to conventional care, should be advocated in the European Guidelines for the treatment of chronic low back pain.[32]
Cherkin et al studied the importance of needle placement and skin penetration in eliciting acupuncture effects for 638 adult patients with mechanical chronic low back pain.[33] The patients were randomized to individualized acupuncture, standardized acupuncture, simulated acupuncture, or usual care, receiving 10 treatments over a 7-week period as administered by experienced acupuncturists.
The investigators reported that individuals receiving real or simulated acupuncture (60%) were more likely than those receiving usual care (39%) to experience clinically meaningful improvements on the dysfunction scale (P < 0.001).[33] Cherkin et al found that although acupuncture was found effective for chronic low back pain, tailoring needling sites to each patient and penetration of the skin appeared to be unimportant in eliciting therapeutic benefits—which raises the question of whether acupuncture or simulated acupuncture provides physiologically important stimulation or whether it represents placebo or nonspecific effects.
Physical therapy
A Boston overlapping brace is used to immobilize the pelvis for prevention of hyperextension and is worn in 0° lordosis for 23 hours per day and for as long as the patient is totally symptom free for a minimum of 3 months, after which a repeat bone scan is performed. Hamstring stretching and lumbar flexibility motions are performed in the brace. Most patients are said to have normal findings on scanning within 3-9 months.[11] Aquatic rehabilitation can also be performed in the acute phase.
Exercise programs have also been used in the treatment of chronic low back pain. Sertpoyraz et al compared the effectiveness of an isokinetic exercise program with a standard exercise regimen in 40 patients with chronic low back pain using the parameters of pain, mobility, disability, psychologic status, and muscle strength.[34] The investigators found both isokinetic and standard exercise resulted in significant improvement compared with the baseline that persisted until the end of the first month. However, comparison of both exercise groups at the end of the treatment and at the first month after treatment showed no significant difference. Sertpoyraz et al concluded that isokinetic and standard exercise are equally effective in the treatment of low back pain; however, in terms of ease of use and cost, standard exercise programs were the preferred option for exercise.[34]
Consultations
Consult neurosurgeons, orthopedic surgeons, neurologists, and physiatrists as indicated.
Recovery Phase
Rehabilitation Program
Physical Therapy
Recovery phase
The goals of the recovery phase are the resolution of pain and the healing of the pars defect with either bony union or painless fibrous union if bony union is not possible.
Physical therapy
This phase of rehabilitation consists of a progressively shallower aquatic rehabilitation location so that graded gravitational forces are applied to the spine. Also, lumbar flexibility out of the brace as symptoms resolve is helpful, but inciting activities must still be avoided. Flexibility and strengthening of the paraspinal, iliopsoas, and abdominal muscles along with endurance training of the back (necessitated by deconditioning) are all especially important. One may advance to full participation in a brace as symptoms resolve.
Consultations
Consult neurosurgeons, orthopedic surgeons, neurologists, and physiatrists as indicated.
Other Treatment (Injection, manipulation, etc.)
Electromagnetic field therapy for persistent nonunion may be used in this phase.
Maintenance Phase
Rehabilitation Program
Physical Therapy
Maintenance phase
The single best predictor for a new injury during athletic activity is a history of a previous injury. Patients showing a spondylolytic defect on plain radiography but whose bone scanning result is negative are regarded as having an inactive spondylolytic defect[11] or a pseudoarthrosis or old unhealed fracture.[30]
Physical therapy
Continue bracing for up to 6-9 months is indicated as necessary to heal the pars. These patients benefit from physical therapy that puts emphasis in deep abdominal muscles, specifically the internal oblique and transversus abdominis and the lumbar multifidus,[35] in addition to flexibility exercises for the hamstrings and lower back. Hyperextension movements are to be avoided. One may need SPECT bone scanning or CT scanning to monitor healing.
Surgical Intervention
Some investigators advocate surgery to prevent spondylolisthesis.[30]
Consultations
Consult neurosurgeons, orthopedic surgeons, neurologists, and physiatrists as indicated.
Other Treatment
Lumbar corsets and neoprene belts are also used.[11]
Arriaza BT. Spondylolysis in prehistoric human remains from Guam and its possible etiology. Am J Phys Anthropol. Nov 1997;104(3):393-7. [Medline].
Morita T, Ikata T, Katoh S, Miyake R. Lumbar spondylolysis in children and adolescents. J Bone Joint Surg Br. Jul 1995;77(4):620-5. [Medline].
Aihara T, Takahashi K, Yamagata M, Moriya H, Tamaki T. Biomechanical functions of the iliolumbar ligament in L5 spondylolysis. J Orthop Sci. 2000;5(3):238-42. [Medline].
Lonstein JE. Spondylolisthesis in children. Cause, natural history, and management. Spine. Dec 15 1999;24(24):2640-8. [Medline].
DeLisa JA, Gans BM, eds. Rehabilitation Medicine: Principles and Practice. 3rd ed. Philadelphia, Pa: Lippincott-Raven; 1998:1646.
Smith JA, Hu SS. Management of spondylolysis and spondylolisthesis in the pediatric and adolescent population. Orthop Clin North Am. Jul 1999;30(3):487-99, ix. [Medline].
Dubousset J. Treatment of spondylolysis and spondylolisthesis in children and adolescents. Clin Orthop Relat Res. Apr 1997;337:77-85. [Medline].
Albanese M, Pizzutillo PD. Family study of spondylolysis and spondylolisthesis. J Pediatr Orthop. 1982;2(5):496-9. [Medline].
Stinson JT. Spondylolysis and spondylolisthesis in the athlete. Clin Sports Med. Jul 1993;12(3):517-28. [Medline].
Patel DR, Nelson TL. Sports injuries in adolescents. Med Clin North Am. Jul 2000;84(4):983-1007, viii. [Medline].
Weiker GG. Evaluation and treatment of common spine and trunk problems. Clin Sports Med. Jul 1989;8(3):399-417. [Medline].
Ariyoshi M, Nagata K, Sonoda K, et al. Spondylolysis at three sites in the same lumbar vertebra. Int J Sports Med. Jan 1999;20(1):56-7. [Medline].
Commandre FA, Taillan B, Gagnerie F, et al. Spondylolysis and spondylolisthesis in young athletes: 28 cases. J Sports Med Phys Fitness. Mar 1988;28(1):104-7. [Medline].
Soler T, Calderon C. The prevalence of spondylolysis in the Spanish elite athlete. Am J Sports Med. Jan-Feb 2000;28(1):57-62. [Medline].
Congeni J, McCulloch J, Swanson K. Lumbar spondylolysis. A study of natural progression in athletes. Am J Sports Med. Mar-Apr 1997;25(2):248-53. [Medline].
Rossi F, Dragoni S. Lumbar spondylolysis: occurrence in competitive athletes. Updated achievements in a series of 390 cases. J Sports Med Phys Fitness. Dec 1990;30(4):450-2. [Medline].
Ralston S, Weir M. Suspecting lumbar spondylolysis in adolescent low back pain. Clin Pediatr (Phila). May 1998;37(5):287-93. [Medline].
Omey ML, Micheli LJ, Gerbino PG 2nd. Idiopathic scoliosis and spondylolysis in the female athlete. Tips for treatment. Clin Orthop Relat Res. Mar 2000;372:74-84. [Medline].
Sward L. The thoracolumbar spine in young elite athletes. Current concepts on the effects of physical training. Sports Med. May 1992;13(5):357-64. [Medline].
Mannor DA, Lindenfeld TN. Spinal process apophysitis mimics spondylolysis. Case reports. Am J Sports Med. Mar-Apr 2000;28(2):257-60. [Medline].
Harvey CJ, Richenberg JL, Saifuddin A, Wolman RL. The radiological investigation of lumbar spondylolysis. Clin Radiol. Oct 1998;53(10):723-8. [Medline].
Lowe J, Schachner E, Hirschberg E, Shapiro Y, Libson E. Significance of bone scintigraphy in symptomatic spondylolysis. Spine. Sep 1984;9(6):653-5. [Medline].
Bellah RD, Summerville DA, Treves ST, Micheli LJ. Low-back pain in adolescent athletes: detection of stress injury to the pars interarticularis with SPECT. Radiology. Aug 1991;180(2):509-12. [Medline]. [Full Text].
Collier BD, Johnson RP, Carrera GF, et al. Painful spondylolysis or spondylolisthesis studied by radiography and single-photon emission computed tomography. Radiology. Jan 1985;154(1):207-11. [Medline]. [Full Text].
Elster AD, Jensen KM. Computed tomography of spondylolisthesis: patterns of associated pathology. J Comput Assist Tomogr. Sep-Oct 1985;9(5):867-74. [Medline].
Kalichman L, Li L, Hunter DJ, Been E. Association between computed tomography-evaluated lumbar lordosis and features of spinal degeneration, evaluated in supine position. Spine J. Apr 2011;11(4):308-15. [Medline].
Ulmer JL, Mathews VP, Elster AD, et al. MR imaging of lumbar spondylolysis: the importance of ancillary observations. AJR Am J Roentgenol. Jul 1997;169(1):233-9. [Medline]. [Full Text].
Sairyo K, Sakai T, Yasui N. Conservative treatment of lumbar spondylolysis in childhood and adolescence: the radiological signs which predict healing. J Bone Joint Surg Br. Feb 2009;91(2):206-9. [Medline].
Zehnder SW, Ward CV, Crow AJ, Alander D, Latimer B. Radiographic assessment of lumbar facet distance spacing and pediatric spondylolysis. Spine. Feb 1 2009;34(3):285-90. [Medline].
Dutton JA, Hughes SP, Peters AM. SPECT in the management of patients with back pain and spondylolysis. Clin Nucl Med. Feb 2000;25(2):93-6. [Medline].
[Best Evidence] Khadilkar A, Odebiyi DO, Brosseau L, Wells GA. Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain. Cochrane Database Syst Rev. Oct 8 2008;CD003008. [Medline].
[Best Evidence] Yuan J, Purepong N, Kerr DP, et al. Effectiveness of acupuncture for low back pain: a systematic review. Spine. Nov 1 2008;33(23):E887-900. [Medline].
[Best Evidence] Cherkin DC, Sherman KJ, Avins AL, et al. A randomized trial comparing acupuncture, simulated acupuncture, and usual care for chronic low back pain. Arch Intern Med. May 11 2009;169(9):858-66. [Medline].
[Best Evidence] Sertpoyraz F, Eyigor S, Karapolat H, Capaci K, Kirazli Y. Comparison of isokinetic exercise versus standard exercise training in patients with chronic low back pain: a randomized controlled study. Clin Rehabil. Mar 2009;23(3):238-47. [Medline].
O'Sullivan PB, Phyty GD, Twomey LT, Allison GT. Evaluation of specific stabilizing exercise in the treatment of chronic low back pain with radiologic diagnosis of spondylolysis or spondylolisthesis. Spine. Dec 15 1997;22(24):2959-67. [Medline].
Moeller JL, Rifat SF. Spondylolysis in active adolescents: expediting return to play. Phys Sportsmed. Dec 2001;29(12):27-32.
Buck JE. Direct repair of the defect in spondylolisthesis. Preliminary report. J Bone Joint Surg Br. Aug 1970;52(3):432-7. [Medline]. [Full Text].
Morscher E, Gerber B, Fasel J. Surgical treatment of spondylolisthesis by bone grafting and direct stabilization of spondylolysis by means of a hook screw. Arch Orthop Trauma Surg. 1984;103(3):175-8. [Medline].
Scott JHS. The Edinburgh repair of isthmic (Group II) spondylolysis [abstract]. J Bone Joint Surg Br. June 1987;69:491.
Kakiuchi M. Repair of the defect in spondylolysis. Durable fixation with pedicle screws and laminar hooks. J Bone Joint Surg Am. Jun 1997;79(6):818-25. [Medline].
Wu SS, Lee CH, Chen PQ. Operative repair of symptomatic spondylolysis following a positive response to diagnostic pars injection. J Spinal Disord. Feb 1999;12(1):10-6. [Medline].
Chen JF, Lee ST. A physiological method for the repair of young adult simple isthmic lumbar spondylolysis. Chang Gung Med J. Feb 2000;23(2):92-8. [Medline].
Sales de Gauzy J, Vadier F, Cahuzac JP. Repair of lumbar spondylolysis using Morscher material: 14 children followed for 1-5 years. Acta Orthop Scand. Jun 2000;71(3):292-6. [Medline]. [Full Text].
Fellander-Tsai L, Micheli LJ. Treatment of spondylolysis with external electrical stimulation and bracing in adolescent athletes: a report of two cases. Clin J Sport Med. Jul 1998;8(3):232-4. [Medline].
Micheli LJ, Wood R. Back pain in young athletes. Significant differences from adults in causes and patterns. Arch Pediatr Adolesc Med. Jan 1995;149(1):15-8. [Medline].
[Best Evidence] Calmels P, Queneau P, Hamonet C, et al. Effectiveness of a lumbar belt in subacute low back pain: an open, multicentric, and randomized clinical study. Spine. Feb 1 2009;34(3):215-20. [Medline].
Caterini R, Mancini F, Bisicchia S, Maglione P, Farsetti P. The correlation between exaggerated fluid in lumbar facet joints and degenerative spondylolisthesis: prospective study of 52 patients. J Orthop Traumatol. Jun 2011;12(2):87-91. [Medline]. [Full Text].
El-Rich M, Villemure I, Labelle H, Aubin CE. Mechanical loading effects on isthmic spondylolytic lumbar segment: finite element modelling using a personalised geometry. Comput Methods Biomech Biomed Engin. Feb 2009;12(1):13-23. [Medline].
[Best Evidence] Helmhout PH, Harts CC, Viechtbauer W, Staal JB, de Bie RA. Isolated lumbar extensor strengthening versus regular physical therapy in an army working population with nonacute low back pain: a randomized controlled trial. Arch Phys Med Rehabil. Sep 2008;89(9):1675-85. [Medline].
Kalichman L, Kim DH, Li L, et al. Spondylolysis and spondylolisthesis: prevalence and association with low back pain in the adult community-based population. Spine. Jan 15 2009;34(2):199-205. [Medline].
Physicians' Desk Reference. 54th ed. Montvale, NJ: Medical Economics Co; 2000.
[Best Evidence] Suh KT, Park WW, Kim SJ, et al. Posterior lumbar interbody fusion for adult isthmic spondylolisthesis: a comparison of fusion with one or two cages. J Bone Joint Surg Br. Oct 2008;90(10):1352-6. [Medline].
Wilms G, Maldague B, Parizel P, et al. Hypoplasia of L5 and wedging and pseudospondylolisthesis in patients with spondylolysis: study with MR imaging. AJNR Am J Neuroradiol. Apr 2009;30(4):674-80. [Medline].

