eMedicine Specialties > Pediatrics: General Medicine > Hematology

Thalassemia: Multimedia

Author: Hassan M Yaish, MD, Professor of Pediatrics, University of Utah School of Medicine; Director of Hematology Services, Medical Director, Mountain States Hemophilia and Thrombophilia Treatment Center; Pediatric Hematologist/Oncologist, Department of Pediatrics, Primary Children's Medical Center
Contributor Information and Disclosures

Updated: Jul 29, 2009

Multimedia

<font face="symbol">a</font> chain genes in dupli...Media file 1: a chain genes in duplication on chromosome 16 pairing with non-a chains to produce various normal hemoglobins.
<font face="symbol">a</font> chain genes in dupli...

a chain genes in duplication on chromosome 16 pairing with non-a chains to produce various normal hemoglobins.

<font face="symbol">a</font>- and <font face="sym...Media file 2: a- and b-globin genes (chromosomes 16 and 11, respectively).
<font face="symbol">a</font>- and <font face="sym...

a- and b-globin genes (chromosomes 16 and 11, respectively).

Various mutations in the <font face="symbol">b</f...Media file 3: Various mutations in the b gene that result in b thalassemia.
Various mutations in the <font face="symbol">b</f...

Various mutations in the b gene that result in b thalassemia.

Supra vital stain in hemoglobin H disease that re...Media file 4: Supra vital stain in hemoglobin H disease that reveals Heinz bodies (golf ball appearance).
Supra vital stain in hemoglobin H disease that re...

Supra vital stain in hemoglobin H disease that reveals Heinz bodies (golf ball appearance).

Peripheral blood film in Cooley anemia.Media file 5: Peripheral blood film in Cooley anemia.
Peripheral blood film in Cooley anemia.

Peripheral blood film in Cooley anemia.

Peripheral blood film in thalassemia minor.Media file 6: Peripheral blood film in thalassemia minor.
Peripheral blood film in thalassemia minor.

Peripheral blood film in thalassemia minor.

Peripheral blood film in hemoglobin H disease in ...Media file 7: Peripheral blood film in hemoglobin H disease in a newborn.
Peripheral blood film in hemoglobin H disease in ...

Peripheral blood film in hemoglobin H disease in a newborn.

Peripheral blood in iron deficiency anemia.Media file 8: Peripheral blood in iron deficiency anemia.
Peripheral blood in iron deficiency anemia.

Peripheral blood in iron deficiency anemia.

The classic "hair on end" appearance on plain sku...Media file 9: The classic "hair on end" appearance on plain skull radiographs of a patient with Cooley anemia.
The classic "hair on end" appearance on plain sku...

The classic "hair on end" appearance on plain skull radiographs of a patient with Cooley anemia.

Excessive iron in a bone marrow preparation.Media file 10: Excessive iron in a bone marrow preparation.
Excessive iron in a bone marrow preparation.

Excessive iron in a bone marrow preparation.

More on Thalassemia

Overview: Thalassemia
Differential Diagnoses & Workup: Thalassemia
Treatment & Medication: Thalassemia
Follow-up: Thalassemia
Multimedia: Thalassemia
References

References

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Further Reading

Keywords

Mediterranean anemia, Cooley anemia, anemia, erythroblastemia, hypochromic anemia, microcytic anemia, α thalassemia, alpha thalassemia, β thalassemia, beta thalassemia, thalassemia syndromes, Hb synthesis, thalassemic hemoglobinopathy, β thalassemia major, beta thalassemia major, globin chain, Hb production, hemoglobin synthesis, hypochromasia, thalassemia minor, β+ thalassemia, beta+ thalassemia, β-0 thalassemia, beta-0 thalassemia, hypochromasia, Hb A2, Hb F, RNA-splicing mutations, Hb Malay, Hb E, Hb Knossos, Hb Lepore, red blood cell precursors, bone expansion, iron absorption

transferrin, malaria, Heinz bodies, hydrops fetalis, silent carrier β thalassemia, silent carrier beta thalassemia, cis deletion, reticulocyte, splenomegaly, frontal bossing, dental malocclusion, iron deficiency anemia, fetal Hb, HPFH, chipmunk facies, chelation, extramedullary hematopoiesis, left ventricular wall thickening, hematopoietic stem cell transplantation, HSCT, hepatitis, deferoxamine, DFO, ferritin, deferiprone, DFP, L1, vitamin C deficiency, hepatomegaly, portal fibrosis, labile iron pool, splenectomy, chorionic villus sampling, CVS, Hb H disease, Hb Constant Spring, Hb CS

Contributor Information and Disclosures

Author

Hassan M Yaish, MD, Professor of Pediatrics, University of Utah School of Medicine; Director of Hematology Services, Medical Director, Mountain States Hemophilia and Thrombophilia Treatment Center; Pediatric Hematologist/Oncologist, Department of Pediatrics, Primary Children's Medical Center
Hassan M Yaish, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Society of Hematology, American Society of Pediatric Hematology/Oncology, Michigan State Medical Society, and New York Academy of Sciences
Disclosure: Nothing to disclose.

Medical Editor

J Martin Johnston, MD, Associate Professor of Pediatrics, Mercer University School of Medicine; Director of Pediatric Hematology/Oncology, Backus Children's Hospital; Consulting Oncologist/Hematologist, St Damien's Pediatric Hospital
J Martin Johnston, MD is a member of the following medical societies: American Society of Pediatric Hematology/Oncology
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

James L Harper, MD, Associate Professor, Department of Pediatrics, Division of Hematology/Oncology and Bone Marrow Transplantation, Associate Chairman for Education, Department of Pediatrics, University of Nebraska Medical Center; Assistant Clinical Professor, Department of Pediatrics, Creighton University; Director, Continuing Medical Education, Children's Memorial Hospital; Pediatric Director, Nebraska Regional Hemophilia Treatment Center
James L Harper, MD is a member of the following medical societies: American Academy of Pediatrics, American Association for Cancer Research, American Federation for Clinical Research, American Society of Hematology, American Society of Pediatric Hematology/Oncology, Council on Medical Student Education in Pediatrics, and Hemophilia and Thrombosis Research Society
Disclosure: Nothing to disclose.

CME Editor

Helen SL Chan, MBBS, FRCP(C), FAAP, Senior Scientist, Research Institute; Professor, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Canada
Helen SL Chan, MBBS, FRCP(C), FAAP is a member of the following medical societies: American Academy of Pediatrics, American Association for Cancer Research, American Society of Hematology, and Royal College of Physicians and Surgeons of Canada
Disclosure: Nothing to disclose.

Chief Editor

Max J Coppes, MD, PhD, MBA, Senior Vice President, Children's National Medical Center (Center for Cancer and Blood Disorders); Director, Center for Cancer and Immunology Research, Children's Research Institute, Children's National Medical Center; Professor of Medicine, Oncology, and Pediatrics, Georgetown University
Max J Coppes, MD, PhD, MBA is a member of the following medical societies: American Association for Cancer Research, American Society of Pediatric Hematology/Oncology, and Society for Pediatric Research
Disclosure: Nothing to disclose.

 
 
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