Pediatric Actinomycosis Treatment & Management

  • Author: Jorge M Quinonez, MD; Chief Editor: Russell W Steele, MD   more...
 
Updated: Nov 28, 2011
 

Medical Care

  • In patients whose actinomycosis is not critical, the option to treat medically along with prolonged courses of antibiotics is an acceptable alternative.
  • A combined medical-surgery approach is frequently needed for complicated disease, especially when thoracic, abdominal, or CNS disease is present.
  • The duration of therapy is prolonged and should be extended well beyond resolution of symptoms to decrease the likelihood of recurrence.
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Surgical Care

  • Surgery is indicated for resection of necrotic tissue, debulking of large masses, sinus tract excision, incision and drainage of empyemas, and abscesses and bone curettage.
  • Surgery alone is not curative, and the use of prolonged courses of antibiotics is always required.
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Consultations

  • Pediatric surgeon
  • Pediatric infectious diseases specialist
  • Ear, nose, and throat specialist
  • Dentist and/or maxillofacial surgeon
  • Gynecologist
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Proceed to Medication
 
 
Contributor Information and Disclosures
Author

Jorge M Quinonez, MD  Senior Vice President and Chief Medical Officer, Family Health Centers of Southwest Florida, Inc

Jorge M Quinonez, MD is a member of the following medical societies: American Academy of Pediatrics and Infectious Diseases Society of America

Disclosure: Glaxo Smith Kline Consulting fee Speaking and teaching

Specialty Editor Board

Itzhak Brook, MD, MSc  Professor, Department of Pediatrics, Georgetown University School of Medicine

Itzhak Brook, MD, MSc is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians-American Society of Internal Medicine, American Federation for Clinical Research, American Medical Association, American Society for Microbiology, Armed Forces Infectious Diseases Society, Association of Military Surgeons of the US, Infectious Diseases Society of America, International Immunocompromised Host Society, International Society for Infectious Diseases, Medical Society of the District of Columbia, New York Academy of Sciences, Pediatric Infectious Diseases Society, Society for Ear, Nose and Throat Advances in Children, Society for Experimental Biology and Medicine, Society for Pediatric Research, Southern Medical Association, and Surgical Infection Society

Disclosure: Nothing to disclose.

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Mark R Schleiss, MD  American Legion Chair of Pediatrics, Professor of Pediatrics, Division Director, Division of Infectious Diseases and Immunology, Department of Pediatrics, University of Minnesota Medical School

Mark R Schleiss, MD is a member of the following medical societies: American Pediatric Society, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, and Society for Pediatric Research

Disclosure: Nothing to disclose.

Robert W Tolan Jr, MD  Chief, Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital at Saint Peter's University Hospital; Clinical Associate Professor of Pediatrics, Drexel University College of Medicine

Robert W Tolan Jr, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Society for Microbiology, American Society of Tropical Medicine and Hygiene, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, Phi Beta Kappa, and Physicians for Social Responsibility

Disclosure: Novartis Honoraria Speaking and teaching

Chief Editor

Russell W Steele, MD  Head, Division of Pediatric Infectious Diseases, Ochsner Children's Health Center; Clinical Professor, Department of Pediatrics, Tulane University School of Medicine

Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, and Southern Medical Association

Disclosure: Nothing to disclose.

References
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  2. Siqueira JF, Rocas IN. Polymerase chain reaction detection of Propionibacterium propionicus and Actynomyces radicidentis in primary and persistent endodontic infections. Oral Surg oral Med Oral Pathol Oral Radiol Endod. 2003;96:215-222. [Medline].

  3. Perlow JH, Wigton T, Yordan EL, et al. Disseminated pelvic actinomycosis presenting as metastatic carcinoma: association with the progestasert intrauterine device. Rev Infect Dis. Nov-Dec 1991;13(6):1115-9. [Medline].

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  12. Sakallioglu U, Acikgoz G, Kirtiloglu T, et al. Rare lesions of the oral cavity: case report of an actinomycotic lesion limited to the gingiva. J Oral Sci. Mar 2003;45(1):39-42. [Medline].

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  16. Snape PS. Thoracic actinomycosis: an unusual childhood infection. South Med J. Feb 1993;86(2):222-4. [Medline].

  17. Tanaka-Bandoh K, Watanabe K, Kato N, et al. Susceptibilities of Actinomyces species and Propionibacterium propionicus to antimicrobial agents. Clin Infect Dis. Sep 1997;25 Suppl 2:S262-3. [Medline].

  18. Weese WC, Smith IM. A study of 57 cases of actinomycosis over a 36-year period. A diagnostic 'failure' with good prognosis after treatment. Arch Intern Med. Dec 1975;135(12):1562-8. [Medline].

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