Pediatric Actinomycosis Treatment & Management
- Author: Jorge M Quinonez, MD; Chief Editor: Russell W Steele, MD more...
Medical Care
- In patients whose actinomycosis is not critical, the option to treat medically along with prolonged courses of antibiotics is an acceptable alternative.
- A combined medical-surgery approach is frequently needed for complicated disease, especially when thoracic, abdominal, or CNS disease is present.
- The duration of therapy is prolonged and should be extended well beyond resolution of symptoms to decrease the likelihood of recurrence.
Surgical Care
- Surgery is indicated for resection of necrotic tissue, debulking of large masses, sinus tract excision, incision and drainage of empyemas, and abscesses and bone curettage.
- Surgery alone is not curative, and the use of prolonged courses of antibiotics is always required.
Consultations
- Pediatric surgeon
- Pediatric infectious diseases specialist
- Ear, nose, and throat specialist
- Dentist and/or maxillofacial surgeon
- Gynecologist
Funke G, von Graevenitz A. Infections due to Actinomyces neuii (former "CDC coryneform group 1" bacteria). Infection. Mar-Apr 1995;23(2):73-5. [Medline].
Siqueira JF, Rocas IN. Polymerase chain reaction detection of Propionibacterium propionicus and Actynomyces radicidentis in primary and persistent endodontic infections. Oral Surg oral Med Oral Pathol Oral Radiol Endod. 2003;96:215-222. [Medline].
Perlow JH, Wigton T, Yordan EL, et al. Disseminated pelvic actinomycosis presenting as metastatic carcinoma: association with the progestasert intrauterine device. Rev Infect Dis. Nov-Dec 1991;13(6):1115-9. [Medline].
Kutluhan A, Salviz M, Yalçiner G, Kandemir O, Yesil C. The role of the actinomyces in obstructive tonsillar hypertrophy and recurrent tonsillitis in pediatric population. Int J Pediatr Otorhinolaryngol. Mar 2011;75(3):391-4. [Medline].
Liu V, Val S, Kang K, Velcek F. Case report: actinomycosis of the appendix--an unusual cause of acute appendicitis in children. J Pediatr Surg. Oct 2010;45(10):2050-2. [Medline].
Cintron JR, Del Pino A, Duarte B, et al. Abdominal actinomycosis. Dis Colon Rectum. Jan 1996;39(1):105-8. [Medline].
Henderson SR. Pelvic actinomycosis associated with an intrauterine device. Obstet Gynecol. May 1973;41(5):726-32. [Medline].
Koshi G, Lalitha MK, Samraj T, et al. Brain abscess and other protean manifestations of actinomycosis. Am J Trop Med Hyg. Jan 1981;30(1):139-44. [Medline].
Maxon S, Jacobs R. Actinomycosis. In: Feigin R, Cherry J, Fletcher J, eds. Textbook of Pediatric Infectious Diseases. Philadelphia, Pa: WB Saunders and Co; 1998:1587-90.
Robinson JL, Vaudry WL, Dobrovolsky W. Actinomycosis presenting as osteomyelitis in the pediatric population. Pediatr Infect Dis J. Apr 2005;24(4):365-9. [Medline].
Russo T. Agents of Actinomycosis. In: Mandell G, Bennett J, Dolin R, eds. Principles and Practice of Infectious Diseases. 4th ed. New York, NY: Churchill Livingston; 1995:2280-8.
Sakallioglu U, Acikgoz G, Kirtiloglu T, et al. Rare lesions of the oral cavity: case report of an actinomycotic lesion limited to the gingiva. J Oral Sci. Mar 2003;45(1):39-42. [Medline].
Skoutelis A, Petrochilos J, Bassaris H. Successful treatment of thoracic actinomycosis with ceftriaxone. Clin Infect Dis. Jul 1994;19(1):161-2. [Medline].
Smego RA Jr. Actinomycosis of the central nervous system. Rev Infect Dis. Sep-Oct 1987;9(5):855-65. [Medline].
Smego RA Jr, Foglia G. Actinomycosis. Clin Infect Dis. Jun 1998;26(6):1255-61; quiz 1262-3. [Medline].
Snape PS. Thoracic actinomycosis: an unusual childhood infection. South Med J. Feb 1993;86(2):222-4. [Medline].
Tanaka-Bandoh K, Watanabe K, Kato N, et al. Susceptibilities of Actinomyces species and Propionibacterium propionicus to antimicrobial agents. Clin Infect Dis. Sep 1997;25 Suppl 2:S262-3. [Medline].
Weese WC, Smith IM. A study of 57 cases of actinomycosis over a 36-year period. A diagnostic 'failure' with good prognosis after treatment. Arch Intern Med. Dec 1975;135(12):1562-8. [Medline].

